ID   Q92M54_RHIME            Unreviewed;       483 AA.
AC   Q92M54;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   SubName: Full=Probable homospermidine synthase {ECO:0000313|EMBL:CAC47379.1};
DE            EC=2.5.1.44 {ECO:0000313|EMBL:CAC47379.1};
GN   Name=hss {ECO:0000313|EMBL:CAC47379.1};
GN   ORFNames=SMc04016 {ECO:0000313|EMBL:CAC47379.1};
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834 {ECO:0000313|EMBL:CAC47379.1, ECO:0000313|Proteomes:UP000001976};
RN   [1] {ECO:0000313|EMBL:CAC47379.1, ECO:0000313|Proteomes:UP000001976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021 {ECO:0000313|EMBL:CAC47379.1,
RC   ECO:0000313|Proteomes:UP000001976};
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [2] {ECO:0000313|Proteomes:UP000001976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021 {ECO:0000313|Proteomes:UP000001976};
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL591688; CAC47379.1; -; Genomic_DNA.
DR   RefSeq; NP_386906.1; NC_003047.1.
DR   RefSeq; WP_010970200.1; NC_003047.1.
DR   AlphaFoldDB; Q92M54; -.
DR   EnsemblBacteria; CAC47379; CAC47379; SMc04016.
DR   GeneID; 61604260; -.
DR   KEGG; sme:SMc04016; -.
DR   PATRIC; fig|266834.11.peg.4312; -.
DR   eggNOG; COG5310; Bacteria.
DR   HOGENOM; CLU_046538_0_0_5; -.
DR   OrthoDB; 9767495at2; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0047296; F:homospermidine synthase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.360.30; homospermidine synthase like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR023181; Homospermid_syn-like_C.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001976};
KW   Transferase {ECO:0000313|EMBL:CAC47379.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          16..160
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          164..451
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   483 AA;  54356 MW;  1C430F1B7B096D13 CRC64;
     MADTTYPVYG EITGPIVMIG FGSIGHGTLP LIERHFKYDK NRLIVVEPRE DAKDTEIFVR
     HGVRHVRAAV TRDNYKELLK PLLTEGGGQG FCVNLSVDTS SLDIIKLCRK LDVLYVDTVI
     EPWLGFYFDA EMDNAARTNY ALRETVRREK EKNPGGTTAV STCGANPGMV SWFVKKALLN
     LADDLGLKYE EPHQDDREGW AKLMKKAGVK GVHIAERDTQ RAKHPKPLNV FWNTWSVEGF
     ISEGLQPAEL GWGTHENWMP KNAKKHKKGC KAAIYLEQPG ANTRVRSWCP TPGPQYGFLV
     THNESISIAD FFTVRDKDGE VSYRPTCHYA YHPANDAVLS LHEMFGNGGK AQPELHVLDE
     HELVDGVDEL GVLLYGHAKN AYWYGSRLSL EETRRIAPYQ NATGLQVTSA VLAGMVWALE
     NPKAGIVEAD EMDYKRCLEV QMPYLGPVEG HYTDWTPLDG RPGLFPEDID TKDPWQFRNI
     LVR
//