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Reviewed, UniProtKB/Swiss-Prot Q92LF7 (PROB2_RHIME)

Last modified June 16, 2009. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glutamate 5-kinase 2
    EC=2.7.2.11
Alternative name(s):
    Gamma-glutamyl kinase 2
      Short name=GK 2
Gene names
Name: proB2
Ordered Locus Names: R03106
ORF Names: SMc03252
OrganismRhizobium meliloti (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier382 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline. HAMAP MF_00456

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glutamate 5-kinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Proline biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processproline biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate 5-kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Glutamate 5-kinase 2 HAMAP MF_00456
PRO_0000109716

Sequences

Sequence LengthMass (Da)Tools
Q92LF7-1 [UniParc].

Last modified July 26, 2002. Version 2.
Checksum: 9DE5148CA9ECB292

FASTA26928,953
        10         20         30         40         50         60 
MEDKFDLSSA RLVVVKIGST LVLDRETSGI RSSWLESLTE DVSRLLTRGQ QVVLVSSGAV 

        70         80         90        100        110        120 
AIGSTIVDRL ATYSQVSHKQ AAAALGQVQL THAYSESLKR HGLQVAQLLM GRGDLVDPAH 

       130        140        150        160        170        180 
RLNTRAVLLR LIDLGAVPLV NENDTTATCG TRVGDNDRLA AWIAEIINAD LLILLSNVDG 

       190        200        210        220        230        240 
LFMKDPRNNP LTPMLTEVES ITREIEAMAT QSVDPYSSGG MISKIEAGKI AMNAGCRMII 

       250        260 
ANGTRSHPLY AIESGGPSTH FIPVARDRV 

« Hide

References

Cross-references

Sequence databases

AL591688 Genomic DNA. Translation: CAC47685.1. Different initiation.
RefSeqNP_387212.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1234791.
GenomeReviewsGene locus R03106 in contig AL591688_GR.
KEGGsme:SMc03252.
NMPDRfig|266834.1.peg.4400.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ92LF7.

Enzyme and pathway databases

BioCycSMEL266834:SMC03252-MON.
BRENDA2.7.2.11. 142.

Family and domain databases

HAMAPMF_00456.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu_5kinase.
IPR011529. Glu_5kinase_bact.
IPR019797. Glutamate_5-kinase_CS.
IPR005715. ProB.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
TIGRFAMsTIGR01027. proB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePROB2_RHIME
AccessionPrimary (citable) accession number: Q92LF7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: July 26, 2002
Last modified: June 16, 2009
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents