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Q92JQ8

- FABZ_RICCN

UniProt

Q92JQ8 - FABZ_RICCN

Protein

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

Gene

fabZ

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.UniRule annotation

    Catalytic activityi

    A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl-carrier protein] + H2O.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei49 – 491UniRule annotation

    GO - Molecular functioni

    1. 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity Source: UniProtKB-EC

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-HAMAP
    2. lipid A biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZUniRule annotation (EC:4.2.1.59UniRule annotation)
    Alternative name(s):
    (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydrataseUniRule annotation
    Short name:
    (3R)-hydroxymyristoyl-ACP dehydraseUniRule annotation
    Beta-hydroxyacyl-ACP dehydrataseUniRule annotation
    Gene namesi
    Name:fabZUniRule annotation
    Ordered Locus Names:RC0009
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 1451453-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZPRO_0000091720Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC0009.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92JQ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thioester dehydratase family. FabZ subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0764.
    HOGENOMiHOG000277829.
    KOiK02372.
    OMAiTIEYHMR.
    OrthoDBiEOG6JTCGM.

    Family and domain databases

    Gene3Di3.10.129.10. 1 hit.
    HAMAPiMF_00406. FabZ.
    InterProiIPR013114. FabA_FabZ.
    IPR010084. FabZ.
    IPR029069. HotDog_dom.
    [Graphical view]
    PfamiPF07977. FabA. 1 hit.
    [Graphical view]
    SUPFAMiSSF54637. SSF54637. 1 hit.
    TIGRFAMsiTIGR01750. fabZ. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q92JQ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIIDITEIMD WIPHRYPFLL VDRVLKIDPN KSITGIKNVT VNEPQFTGHF    50
    PARPVMPGVL MVEAMAQLAA ILVAKSLGST KNKEVFLMTI ENAKFRRIVQ 100
    PGDTMHIHAV IDQQRANVWK FSSTVTVEGE IATESKFTAM IKDKT 145
    Length:145
    Mass (Da):16,320
    Last modified:December 1, 2001 - v1
    Checksum:iD4F5D14B03B8A456
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02547.1.
    PIRiA97701.
    RefSeqiNP_359646.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02547; AAL02547; RC0009.
    GeneIDi928657.
    KEGGirco:RC0009.
    PATRICi17887084. VBIRicCon45613_0008.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02547.1 .
    PIRi A97701.
    RefSeqi NP_359646.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92JQ8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0009.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02547 ; AAL02547 ; RC0009 .
    GeneIDi 928657.
    KEGGi rco:RC0009.
    PATRICi 17887084. VBIRicCon45613_0008.

    Phylogenomic databases

    eggNOGi COG0764.
    HOGENOMi HOG000277829.
    KOi K02372.
    OMAi TIEYHMR.
    OrthoDBi EOG6JTCGM.

    Family and domain databases

    Gene3Di 3.10.129.10. 1 hit.
    HAMAPi MF_00406. FabZ.
    InterProi IPR013114. FabA_FabZ.
    IPR010084. FabZ.
    IPR029069. HotDog_dom.
    [Graphical view ]
    Pfami PF07977. FabA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54637. SSF54637. 1 hit.
    TIGRFAMsi TIGR01750. fabZ. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiFABZ_RICCN
    AccessioniPrimary (citable) accession number: Q92JQ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 31, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3