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Q92JQ6

- DUS_RICCN

UniProt

Q92JQ6 - DUS_RICCN

Protein

Probable tRNA-dihydrouridine synthase

Gene

dus

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 2 (20 Mar 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.By similarity

    Cofactori

    FAD.By similarity

    GO - Molecular functioni

    1. flavin adenine dinucleotide binding Source: InterPro
    2. tRNA dihydrouridine synthase activity Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable tRNA-dihydrouridine synthase (EC:1.-.-.-)
    Gene namesi
    Name:dus
    Ordered Locus Names:RC0011
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 331331Probable tRNA-dihydrouridine synthasePRO_0000162140Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC0011.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92JQ6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Dus family.Curated

    Phylogenomic databases

    eggNOGiCOG0042.
    HOGENOMiHOG000217855.
    KOiK05540.
    OMAiYVCEMIT.
    OrthoDBiEOG6VHZFQ.

    Family and domain databases

    Gene3Di1.10.1200.80. 1 hit.
    3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR024036. tRNA-dHydroUridine_Synthase_C.
    IPR004652. tRNA_dU_NifR3.
    IPR001269. tRNA_hU_synthase.
    IPR018517. tRNA_hU_synthase_CS.
    [Graphical view]
    PANTHERiPTHR11082. PTHR11082. 1 hit.
    PfamiPF01207. Dus. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006621. Dus. 1 hit.
    TIGRFAMsiTIGR00737. nifR3_yhdG. 1 hit.
    PROSITEiPS01136. UPF0034. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92JQ6-1 [UniParc]FASTAAdd to Basket

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    MIKIGNIELS SNIILAPMSG VTDLEFRRLV KRFGAGLVVS EMVASRAMIV    50
    ESRQSLKKSA IMRDDATSAC VQLAGCEPNV IAEAAKMNEG MGAKIIDLNF 100
    GCPAKKVVGG YSGSALMKDE QLAAKIFEAT VEAVKLPVTV KMRMGWDDNT 150
    KNAPTLAKIA ESSGVQMITV HGRTRCQFYS GNADWDFIRS VKESVKIPVI 200
    ANGDITNFAK AKEALQKSGA DGIMVGRGAY GKPWLISQID HYLKTGEEKS 250
    APSIAEQLDI VTEHYEAILD YYGESVGVPI ARKHIGWYSS GLPNSAEFRG 300
    AVNLMNDPLA VKEKIAEFYT SVMETNKLKE F 331
    Length:331
    Mass (Da):35,995
    Last modified:March 20, 2007 - v2
    Checksum:i4B6149340754AB59
    GO

    Sequence cautioni

    The sequence AAL02549.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02549.1. Different initiation.
    PIRiC97701.
    RefSeqiNP_359648.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02549; AAL02549; RC0011.
    GeneIDi928651.
    KEGGirco:RC0011.
    PATRICi17887092. VBIRicCon45613_0011.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02549.1 . Different initiation.
    PIRi C97701.
    RefSeqi NP_359648.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92JQ6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0011.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02549 ; AAL02549 ; RC0011 .
    GeneIDi 928651.
    KEGGi rco:RC0011.
    PATRICi 17887092. VBIRicCon45613_0011.

    Phylogenomic databases

    eggNOGi COG0042.
    HOGENOMi HOG000217855.
    KOi K05540.
    OMAi YVCEMIT.
    OrthoDBi EOG6VHZFQ.

    Family and domain databases

    Gene3Di 1.10.1200.80. 1 hit.
    3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR024036. tRNA-dHydroUridine_Synthase_C.
    IPR004652. tRNA_dU_NifR3.
    IPR001269. tRNA_hU_synthase.
    IPR018517. tRNA_hU_synthase_CS.
    [Graphical view ]
    PANTHERi PTHR11082. PTHR11082. 1 hit.
    Pfami PF01207. Dus. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006621. Dus. 1 hit.
    TIGRFAMsi TIGR00737. nifR3_yhdG. 1 hit.
    PROSITEi PS01136. UPF0034. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiDUS_RICCN
    AccessioniPrimary (citable) accession number: Q92JQ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2003
    Last sequence update: March 20, 2007
    Last modified: October 1, 2014
    This is version 69 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3