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Q92JQ6

- DUS_RICCN

UniProt

Q92JQ6 - DUS_RICCN

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Protein

Probable tRNA-dihydrouridine synthase

Gene

dus

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.By similarity

Cofactori

FAD.By similarity

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: InterPro
  2. tRNA dihydrouridine synthase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA-dihydrouridine synthase (EC:1.-.-.-)
Gene namesi
Name:dus
Ordered Locus Names:RC0011
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 331331Probable tRNA-dihydrouridine synthasePRO_0000162140Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0011.

Structurei

3D structure databases

ProteinModelPortaliQ92JQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Dus family.Curated

Phylogenomic databases

eggNOGiCOG0042.
HOGENOMiHOG000217855.
KOiK05540.
OMAiYVCEMIT.
OrthoDBiEOG6VHZFQ.

Family and domain databases

Gene3Di1.10.1200.80. 1 hit.
3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR024036. tRNA-dHydroUridine_Synthase_C.
IPR004652. tRNA_dU_NifR3.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view]
PANTHERiPTHR11082. PTHR11082. 1 hit.
PfamiPF01207. Dus. 1 hit.
[Graphical view]
PIRSFiPIRSF006621. Dus. 1 hit.
TIGRFAMsiTIGR00737. nifR3_yhdG. 1 hit.
PROSITEiPS01136. UPF0034. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92JQ6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIKIGNIELS SNIILAPMSG VTDLEFRRLV KRFGAGLVVS EMVASRAMIV
60 70 80 90 100
ESRQSLKKSA IMRDDATSAC VQLAGCEPNV IAEAAKMNEG MGAKIIDLNF
110 120 130 140 150
GCPAKKVVGG YSGSALMKDE QLAAKIFEAT VEAVKLPVTV KMRMGWDDNT
160 170 180 190 200
KNAPTLAKIA ESSGVQMITV HGRTRCQFYS GNADWDFIRS VKESVKIPVI
210 220 230 240 250
ANGDITNFAK AKEALQKSGA DGIMVGRGAY GKPWLISQID HYLKTGEEKS
260 270 280 290 300
APSIAEQLDI VTEHYEAILD YYGESVGVPI ARKHIGWYSS GLPNSAEFRG
310 320 330
AVNLMNDPLA VKEKIAEFYT SVMETNKLKE F
Length:331
Mass (Da):35,995
Last modified:March 20, 2007 - v2
Checksum:i4B6149340754AB59
GO

Sequence cautioni

The sequence AAL02549.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL02549.1. Different initiation.
PIRiC97701.
RefSeqiNP_359648.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02549; AAL02549; RC0011.
GeneIDi928651.
KEGGirco:RC0011.
PATRICi17887092. VBIRicCon45613_0011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL02549.1 . Different initiation.
PIRi C97701.
RefSeqi NP_359648.1. NC_003103.1.

3D structure databases

ProteinModelPortali Q92JQ6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0011.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL02549 ; AAL02549 ; RC0011 .
GeneIDi 928651.
KEGGi rco:RC0011.
PATRICi 17887092. VBIRicCon45613_0011.

Phylogenomic databases

eggNOGi COG0042.
HOGENOMi HOG000217855.
KOi K05540.
OMAi YVCEMIT.
OrthoDBi EOG6VHZFQ.

Family and domain databases

Gene3Di 1.10.1200.80. 1 hit.
3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR024036. tRNA-dHydroUridine_Synthase_C.
IPR004652. tRNA_dU_NifR3.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view ]
PANTHERi PTHR11082. PTHR11082. 1 hit.
Pfami PF01207. Dus. 1 hit.
[Graphical view ]
PIRSFi PIRSF006621. Dus. 1 hit.
TIGRFAMsi TIGR00737. nifR3_yhdG. 1 hit.
PROSITEi PS01136. UPF0034. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiDUS_RICCN
AccessioniPrimary (citable) accession number: Q92JQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: March 20, 2007
Last modified: October 1, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3