Reviewed, UniProtKB/Swiss-Prot Q92JP8 (SCA1_RICCN)

Names and origin

Protein names

Recommended name:
    Putative surface cell antigen sca1

Gene names

Name:	sca1
Ordered Locus Names:	RC0019

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	1902 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell outer membrane By similarity.
Sequence similarities	Contains 1 autotransporter (TC 1.B.12) domain. [View classification]

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 1902	1874	Putative surface cell antigen sca1		PRO_0000259742
Regions
	Domain	1618 – 1902	285	Autotransporter

Sequences

	Sequence		Length	Mass (Da)
	Q92JP8-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: F2D817457EF1912A	FASTA	1,902	212,153
	10 20 30 40 50 60 MNKLTEQHLL KKSRFLKYSL LASISVGAAI PFEGMAMSKE AFRIDLSNKL LNHVSQLNGY 70 80 90 100 110 120 KDTTNNTPQQ IGKVIVSEPK INTYTPSEIR EMKISNKPKA SNPLKDVPIE DHYKVVARSK 130 140 150 160 170 180 SDVGTARKVR PITRCKTFAG IEKTEQSQNT YTPESTEQMP QKPEIIITAS SPTVSPASNS 190 200 210 220 230 240 FITAPNTPNT TLTSPEHYTT APGTPSSTPA TPYQSTSDSK PNDSLGANTP PNINTNSKAV 250 260 270 280 290 300 RRLSFSSSGP QQQAVQSSSQ VKSEVPPKPT FVPLPIKKSS TEIVAGMVSN ISRVNEMIGI 310 320 330 340 350 360 KLAEVTQAID TTDKKDKERL QKLYTQLTST QKTTEKLKSR AEEIETKIKI GENKDKIKKL 370 380 390 400 410 420 EKELTSKNNK ADRLFQKIEK IDIPANKVSI KSQETVPVTT ASTEVSAFQA QQARINEARQ 430 440 450 460 470 480 GVFNKNKSSG GNARKSSAGT KREKKKQEAQ KQLSEIKKQE KAIKTASDKA KEVAASAKKE 490 500 510 520 530 540 TSRTALRAMQ DKMNGDSEQL NKIEENLKLL TPVVYNSSTG PTYKQSPKAT PTIPLSHGVQ 550 560 570 580 590 600 RILGEQPEDE EGYLVPIKVQ QQPYQEIEDP IPSHSKDIYE AKVSQYINYL NSIQPNQSNQ 610 620 630 640 650 660 AQIDSVIDGL ATEMRKFSAD QFSQKLGEIA HLASIKAYEG LFEKLYEIQQ ARILETQKVY 670 680 690 700 710 720 EQAEISQSYA EYEENSRKSS IPVLSRSSSA KSVISSNFEE KSALLQTTTT DESLRSDNNW 730 740 750 760 770 780 KNSAPYSSSP KLDKRGLEYL DLAGDAFVQN LKQPDTLTIE TLGLITPTQN TTVAKSDSSR 790 800 810 820 830 840 KNNVSGSISE IQQLQSEKMR TETLGVQDDL GLDLHYTPQE TLTEKSTYLV SSKKKQGNII 850 860 870 880 890 900 KRAVSKVGSI LQTNYAENRR RKRDGETSKQ RTVDQEGEFG HAWGNENHKE SSLSVVSGCI 910 920 930 940 950 960 KKATQLISLL DAKRTAILQT TSPSQRRSVS LVLQEIENDY REAIKISQKL QQVLIRKPED 970 980 990 1000 1010 1020 IKAYNAKAEK KLDAIKSRAD KHFNNIETDV DVGFNPNGGN SHSMPTANMD ILPKNLAVTP 1030 1040 1050 1060 1070 1080 PTNVGSLYNS PQAQQFQEDH KNIIINDRSQ GRLNLVDSTI VRELTDVDAS IYNTAPPEVL 1090 1100 1110 1120 1130 1140 KEAEALLDRS QGRLNLVDNT IKKGTQPLSN LSTIYESVSY ENLASETIYK TEQPKPSISY 1150 1160 1170 1180 1190 1200 TNTSKRKLPI PLFRSAELDK KLEYLDLEDK LLEVEEARIV KEKEAIAKLN QYQDPENLEF 1210 1220 1230 1240 1250 1260 KRLAMEALDL SSKESQLKQK RKAIEAEFSL NEKSSSTDVS ILRSYSIDDI SGVLSDAESN 1270 1280 1290 1300 1310 1320 LSRSPSVSGL EDLNNSNVMQ LEELKSKHEK IANDYNKELE LDTLNKEKIW LEGEIKHLDT 1330 1340 1350 1360 1370 1380 EFKPKVTESK PVFSCSSSVG SINSFSNDDD LSSRDVVTPV DTLNIEINKD YVDTYIRVLS 1390 1400 1410 1420 1430 1440 NKIQKIEEIQ KIEELSGSSS RSEELNHIKE AMAYISNRIQ DVEELDEKML LAINAQLQEH 1450 1460 1470 1480 1490 1500 DEKISSLLRE EATDILAQLL LQEMLVSDGK SESTLPAGDE EQEDTEVSRQ LSSLPALASS 1510 1520 1530 1540 1550 1560 NESALALSDD REKECLALGD SSEDEESYDS GFEEEEETIG QLSDSDGDNL KITEVDTVIP 1570 1580 1590 1600 1610 1620 LEQEAKKEMQ TQISENAPTL NQAKVVNTIV NNMIRNRLDA SMNMSNNMVA VGAGDEEESH 1630 1640 1650 1660 1670 1680 IKRGLWMRGM YGTNNHGRVE NMTGYRGTNK GATIGFDAEI DNNIVGIAYS NVHSVFKFKN 1690 1700 1710 1720 1730 1740 SKNNDKELIN SHVVSIYGQK ELPKNFALQA LVSASKNFIK DKTTYSYGDT KIKSNVKHRN 1750 1760 1770 1780 1790 1800 HSYNAEALLH YNYLLQSKLV ITPNIGLRYG KSRDGVYNET GVNVQEIALT MKENNILSGI 1810 1820 1830 1840 1850 1860 VGTKVTVPLK DALKFNNLGL IFQGAVEHNF KEKTQRINRV VKIFDNTFKH NYLIPKQPKT 1870 1880 1890 1900 SYNLGTGIIG SIKNTTISLD YNYYLNKHYR SHQGSVKLKV NL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.
[2]	"Sca1, a previously undescribed paralog from autotransporter protein-encoding genes in Rickettsia species." Ngwamidiba M., Blanc G., Raoult D., Fournier P.-E. BMC Microbiol. 6:12-12(2006) [PubMed: 16504018] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1629-1790, TRANSCRIPTION. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL02557.1. DQ306906 Genomic DNA. Translation: ABC41076.1.
PIR	C97702.
RefSeq	NP_359656.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	928642.
GenomeReviews	Gene locus RC0019 in contig AE006914_GR.
KEGG	rco:RC0019.
NMPDR	fig|272944.1.peg.19.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q92JP8.
OMA	EQEDTEV
Enzyme and pathway databases
BioCyc	RCON272944:RC0019-MON.
Family and domain databases
InterPro	IPR020179. Ag_surface_cell_prcur_Sca1. IPR005546. Auto_transptbeta. IPR006315. OM_autotransptr_brl. [Graphical view]
Pfam	PF03797. Autotransporter. 1 hit. [Graphical view]
ProDom	PD214418. Ag_surface_cell_prcur_sca1. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00869. Autotransporter. 1 hit. [Graphical view]
TIGRFAMs	TIGR01414. autotrans_barl. 1 hit.
PROSITE	PS51208. AUTOTRANSPORTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCA1_RICCN

Accession

Primary (citable) accession number: Q92JP8
Secondary accession number(s): Q20DN5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	December 1, 2001
Last modified:	November 24, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)