Reviewed, UniProtKB/Swiss-Prot Q92JP0 (ATP6_RICCN)

Names and origin

Protein names

Recommended name:
    ATP synthase subunit a
Alternative name(s):
    F-ATPase subunit 6
    ATP synthase F0 sector subunit a

Gene names

Name:	atpB
Ordered Locus Names:	RC0027

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane By similarity.
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the ATPase A chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	ATP synthase subunit a HAMAP MF_01393		PRO_0000082068
Regions
	Transmembrane	29 – 49	21	Potential
	Transmembrane	84 – 104	21	Potential
	Transmembrane	114 – 134	21	Potential
	Transmembrane	140 – 160	21	Potential
	Transmembrane	181 – 201	21	Potential
	Transmembrane	203 – 223	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92JP0-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 385920FAD422A832	FASTA	242	27,410
	10 20 30 40 50 60 MTHSPLAQFD IKKLIDIKMF GFDVSFTNSS IYMLLASILA LTYFYLAFYN RKLVPSRLQV 70 80 90 100 110 120 SAEIVYNLVA DMLNQNIGVK GRKFIPLVFS LFIFILFCNL LGMTPYSFTT TSHIIVTFTL 130 140 150 160 170 180 AILVFLMVTI VGFVKHGLRF LTLFLPHGTP LWLAPLMIVI ELFTYLARPV SLSLRLAANM 190 200 210 220 230 240 MAGHVLLKVI AGFTVSLMIY LKFLPIPIMV ILIGFEIFVA ILQAYIFTIL SCMYLNDAIN LH

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL02565.1.
PIR	C97703.
RefSeq	NP_359664.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	928638.
GenomeReviews	Gene locus RC0027 in contig AE006914_GR.
KEGG	rco:RC0027.
NMPDR	fig|272944.1.peg.27.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q92JP0.
OMA	AFYNRKL
Enzyme and pathway databases
BioCyc	RCON272944:RC0027-MON.
BRENDA	3.6.3.14. 267518.
Family and domain databases
HAMAP	MF_01393. [Tree]
InterPro	IPR000568. ATPase_F0-cplx_asu. [Graphical view]
Gene3D	G3DSA:1.20.120.220. ATPase_F0_A. 1 hit.
PANTHER	PTHR11410. ATPase_F0_A. 1 hit.
Pfam	PF00119. ATP-synt_A. 1 hit. [Graphical view]
PRINTS	PR00123. ATPASEA.
TIGRFAMs	TIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITE	PS00449. ATPASE_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATP6_RICCN

Accession

Primary (citable) accession number: Q92JP0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
Last sequence update:	December 1, 2001
Last modified:	November 24, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)