Q92JN8 (DSB_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative protein-disulfide oxidoreductase RC0029
EC=1.8.-.-

Gene names

Ordered Locus Names:

RC0029

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be required for disulfide bond formation in some proteins By similarity.
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the thioredoxin family. DsbA subfamily. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Redox-active center Signal
Molecular function	Oxidoreductase
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular_component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 277	255	Putative protein-disulfide oxidoreductase RC0029		PRO_0000259988
Regions
	Domain	76 – 265	190	Thioredoxin
Amino acid modifications
	Disulfide bond	118 ↔ 121		Redox-active Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92JN8 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 83D5B0D06908CBD7	FASTA	277	31,198
	10 20 30 40 50 60 MRSIFIILIF LLFLSSCSEE KAQDKNHEEK QIIEHETQNN ETSKATNQEA VNSENTTESI 70 80 90 100 110 120 VPANDNNQTD EVSTPASQKQ KNPAIKAVKV TFKVDDNDMV LGNKKSNVIV VEYFSPTCPH 130 140 150 160 170 180 CAYYHQTIFP ELKKKYIDTN KIAYVVREFI ATKQDLDAAI LARCKGDTNS FTQLHNIILI 190 200 210 220 230 240 QQDKWAYSNK YRELLTDIGQ LGGISPEEYK QCLNNDKITA ILIANTNFVA KAPQFIGTPS 250 260 270 FFVNGVQTGN YSIDTISTAV DKALEEQKEK AKNEMSL

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL02567.1.
PIR	E97703.
RefSeq	NP_359666.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92JN8.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC0029.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL02567; AAL02567; RC0029.
GeneID	928636.
KEGG	rco:RC0029.
PATRIC	17887144. VBIRicCon45613_0036.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1651.
HOGENOM	HOG000272918.
OMA	AYYHQTI.
ProtClustDB	CLSK870708.
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
InterPro	IPR012336. Thioredoxin-like_fold. IPR017937. Thioredoxin_CS. [Graphical view]
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS00194. THIOREDOXIN_1. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DSB_RICCN

Accession

Primary (citable) accession number: Q92JN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program