Reviewed, UniProtKB/Swiss-Prot Q92JN8 (DSB_RICCN)

Names and origin

Protein names

Recommended name:
    Putative protein-disulfide oxidoreductase RC0029
    EC=1.8.-.-

Gene names

Ordered Locus Names:

RC0029

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	May be required for disulfide bond formation in some proteins By similarity.
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the thioredoxin family. DsbA subfamily. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Redox-active center Signal
Molecular function	Oxidoreductase
PTM	Disulfide bond
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 277	255	Putative protein-disulfide oxidoreductase RC0029		PRO_0000259988
Regions
	Domain	76 – 265	190	Thioredoxin
Amino acid modifications
	Disulfide bond	118 ↔ 121		Redox-active Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92JN8-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 83D5B0D06908CBD7	FASTA	277	31,198
	10 20 30 40 50 60 MRSIFIILIF LLFLSSCSEE KAQDKNHEEK QIIEHETQNN ETSKATNQEA VNSENTTESI 70 80 90 100 110 120 VPANDNNQTD EVSTPASQKQ KNPAIKAVKV TFKVDDNDMV LGNKKSNVIV VEYFSPTCPH 130 140 150 160 170 180 CAYYHQTIFP ELKKKYIDTN KIAYVVREFI ATKQDLDAAI LARCKGDTNS FTQLHNIILI 190 200 210 220 230 240 QQDKWAYSNK YRELLTDIGQ LGGISPEEYK QCLNNDKITA ILIANTNFVA KAPQFIGTPS 250 260 270 FFVNGVQTGN YSIDTISTAV DKALEEQKEK AKNEMSL

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL02567.1.
PIR	E97703.
RefSeq	NP_359666.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	928636.
GenomeReviews	Gene locus RC0029 in contig AE006914_GR.
KEGG	rco:RC0029.
NMPDR	fig|272944.1.peg.29.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	TLIANTN.
Enzyme and pathway databases
BioCyc	RCON272944:RC0029-MON.
Family and domain databases
InterPro	IPR017936. Thioredoxin-like. IPR012336. Thioredoxin-like_fold. IPR017937. Thioredoxin_CS. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PROSITE	PS00194. THIOREDOXIN_1. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DSB_RICCN

Accession

Primary (citable) accession number: Q92JN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	December 1, 2001
Last modified:	December 15, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)