Reviewed,
UniProtKB/Swiss-Prot Q92JJ9 (FTSH_RICCN)
Last modified
November 24, 2009.
Version 59.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Cell division protease ftsH homolog EC=3.4.24.- | ||||
| Gene names |
| ||||
| Organism | Rickettsia conorii [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 781 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group |
Protein attributes
| Sequence length | 637 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Seems to act as an ATP-dependent zinc metallopeptidase By similarity. |
| Cofactor | Binds 1 zinc ion per subunit Potential. |
| Subcellular location | |
| Sequence similarities | In the N-terminal section; belongs to the AAA ATPase family. In the C-terminal section; belongs to the peptidase M41 family. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 637 | 637 | Cell division protease ftsH homolog | PRO_0000084645 | |||||
Regions | |||||||||
| Topological domain | 1 – 6 | 6 | Cytoplasmic Potential | ||||||
| Transmembrane | 7 – 27 | 21 | Potential | ||||||
| Topological domain | 28 – 103 | 76 | Extracellular Potential | ||||||
| Transmembrane | 104 – 124 | 21 | Potential | ||||||
| Topological domain | 125 – 637 | 513 | Cytoplasmic Potential | ||||||
| Nucleotide binding | 195 – 202 | 8 | ATP Potential | ||||||
Sites | |||||||||
| Active site | 418 | 1 | By similarity | ||||||
| Metal binding | 417 | 1 | Zinc; catalytic By similarity | ||||||
| Metal binding | 421 | 1 | Zinc; catalytic By similarity | ||||||
Sequences
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References
| [1] | "Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7. |
Cross-references
Sequence databases | |
|---|---|
| AE006914 Genomic DNA. Translation: AAL02606.1. | |
| PIR | D97708. |
| RefSeq | NP_359705.1. |
3D structure databases | |
| ModBase | Search... |
Protein family/group databases | |
| MEROPS | M41.001. |
Genome annotation databases | |
| GeneID | 928595. |
| GenomeReviews | Gene locus RC0068 in contig AE006914_GR. |
| KEGG | rco:RC0068. |
| NMPDR | fig|272944.1.peg.68. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q92JJ9. |
| OMA | YISDETK |
Enzyme and pathway databases | |
| BioCyc | RCON272944:RC0068-MON. |
Family and domain databases | |
| InterPro | IPR003593. ATPase_AAA+_core. IPR003959. ATPase_AAA_core. IPR003960. ATPase_AAA_CS. IPR005936. Pept_M41_FtsH. IPR011546. Pept_M41_FtsH_extracell. IPR000642. Peptidase_M41. [Graphical view] |
| Pfam | PF00004. AAA. 1 hit. PF06480. FtsH_ext. 1 hit. PF01434. Peptidase_M41. 1 hit. [Graphical view] |
| SMART | SM00382. AAA. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01241. FtsH_fam. 1 hit. |
| PROSITE | PS00674. AAA. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | FTSH_RICCN | ||||||||
| Accession | Primary (citable) accession number: Q92JJ9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Rickettsia conorii (strain Malish 7): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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