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Protein

Prolipoprotein diacylglyceryl transferase

Gene

lgt

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. lipoprotein biosynthetic process Source: UniProtKB-HAMAP
  2. protein lipoylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

UniPathwayiUPA00664.

Names & Taxonomyi

Protein namesi
Recommended name:
Prolipoprotein diacylglyceryl transferaseUniRule annotation (EC:2.4.99.-UniRule annotation)
Gene namesi
Name:lgtUniRule annotation
Ordered Locus Names:RC0072
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3523HelicalUniRule annotationAdd
BLAST
Transmembranei55 – 7420HelicalUniRule annotationAdd
BLAST
Transmembranei94 – 11118HelicalUniRule annotationAdd
BLAST
Transmembranei118 – 14023HelicalUniRule annotationAdd
BLAST
Transmembranei173 – 19220HelicalUniRule annotationAdd
BLAST
Transmembranei199 – 22123HelicalUniRule annotationAdd
BLAST
Transmembranei231 – 25323HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Prolipoprotein diacylglyceryl transferasePRO_0000172663Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0072.

Family & Domainsi

Sequence similaritiesi

Belongs to the Lgt family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0682.
HOGENOMiHOG000098666.
KOiK13292.
OMAiHWYGLAY.
OrthoDBiEOG6MH5CQ.

Family and domain databases

HAMAPiMF_01147. Lgt.
InterProiIPR001640. Prolipoprot_diAcglycer_Trfase.
[Graphical view]
PfamiPF01790. LGT. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00544. lgt. 1 hit.
PROSITEiPS01311. LGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92JJ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTFPNINPII FSIGPLAISW YSLSYVIGIL LGWFYANKIV EKFKPQITKK
60 70 80 90 100
NLEDFITYAV IGIIVGGRLG FVLLYNPSRY FSNPIDILKT YEGGMSFHGG
110 120 130 140 150
ALGGIIAAYL FCRKYKINFL SLTDIIAPVV PIGLFLGRIA NFINGELYGR
160 170 180 190 200
ITNSSFGMIF PNSDLMPRHP SQLYEAFFEG LVLFSILAYT TFKHKTLKKC
210 220 230 240 250
GLNSGIFFTF YGLFRITIEI FREPDIQIGF ILDSLTMGQI LSVPMLLLGS

YLICQSNPK
Length:259
Mass (Da):29,116
Last modified:December 1, 2001 - v1
Checksum:iE71A1198D0670C6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02610.1.
PIRiH97708.
RefSeqiNP_359709.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02610; AAL02610; RC0072.
GeneIDi928588.
KEGGirco:RC0072.
PATRICi17887242. VBIRicCon45613_0085.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02610.1.
PIRiH97708.
RefSeqiNP_359709.1. NC_003103.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272944.RC0072.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL02610; AAL02610; RC0072.
GeneIDi928588.
KEGGirco:RC0072.
PATRICi17887242. VBIRicCon45613_0085.

Phylogenomic databases

eggNOGiCOG0682.
HOGENOMiHOG000098666.
KOiK13292.
OMAiHWYGLAY.
OrthoDBiEOG6MH5CQ.

Enzyme and pathway databases

UniPathwayiUPA00664.

Family and domain databases

HAMAPiMF_01147. Lgt.
InterProiIPR001640. Prolipoprot_diAcglycer_Trfase.
[Graphical view]
PfamiPF01790. LGT. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00544. lgt. 1 hit.
PROSITEiPS01311. LGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiLGT_RICCN
AccessioniPrimary (citable) accession number: Q92JJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: December 1, 2001
Last modified: February 4, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia conorii
    (strain Malish 7): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.