Reviewed, UniProtKB/Swiss-Prot Q92JJ3 (OXAA_RICCN)

Names and origin

Protein names

Recommended name:
    Inner membrane protein oxaA

Gene names

Name:	oxaA
Ordered Locus Names:	RC0074

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	560 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex By similarity.
Subunit structure	Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the OXA1/oxaA family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein insertion into membrane Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 560	560	Inner membrane protein oxaA HAMAP MF_01810		PRO_0000124749
Regions
	Transmembrane	5 – 27	23	Potential
	Transmembrane	358 – 380	23	Potential
	Transmembrane	427 – 449	23	Potential
	Transmembrane	473 – 495	23	Potential
	Transmembrane	522 – 544	23	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92JJ3-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: B521D15A76053C94	FASTA	560	64,444
	10 20 30 40 50 60 MNNNIINLIA AIILSLSIIF GWQYFVVKPE QKKQQQQIAV QKAENLKKQQ LKALVEPATG 70 80 90 100 110 120 IVVQEESQVQ RIKIESESLT GSISLKGLRF DDLILKKYKQ DLSKNSPEVR LFSPANTENA 130 140 150 160 170 180 YFAEVGLVSN LSSVKLPNND TIWNSDSEIL SPEKPVHLFW VNEDGVKFLV TITVDENYLF 190 200 210 220 230 240 TIEQTIVNNS DKELPVQSYG LINRKYIAVE KAVNILHQGP IGCIDENLKE YSYDDIKDKK 250 260 270 280 290 300 SEKFAASKVD WIGITDKYWL SSLIPDKSSN YSSNFNYALK QGTERYQVDF ISPVQIIKPG 310 320 330 340 350 360 ENFSIKSRIF AGAKKVDLLD KYEKQYDIKL FDRAIDFGWF YIITKPVFYA MNFFYGYVGN 370 380 390 400 410 420 FGVSILIVTV IIKLLMFTLA NKSYRSMKKM KNLQPEIDRI KNLYSDDKAR LNQEIMALYK 430 440 450 460 470 480 KEKVNPVAGC LPILVQIPVF FSIYKVLYVT IEMRQAPFYG WIKDLSASDP TTIFNLFGLL 490 500 510 520 530 540 PFSPPSFLMI GAWPILMAIT MFLQQKMSPE PADPMQAQVM KFMPLIFLFM FSSFPVGLLI 550 560 YWSWNNILSI IQQYYINKFN

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL02612.1.
PIR	B97709.
RefSeq	NP_359711.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	928590.
GenomeReviews	Gene locus RC0074 in contig AE006914_GR.
KEGG	rco:RC0074.
NMPDR	fig|272944.1.peg.74.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q92JJ3.
OMA	FVTIEMR
Enzyme and pathway databases
BioCyc	RCON272944:RC0074-MON.
Family and domain databases
HAMAP	MF_01810. [Tree]
InterPro	IPR020001. Membrane_insert_OxaA/YidC_core. IPR001708. Membrane_insertion_OxaA/YidC. IPR013308. Membrane_insertion_YidC. IPR019998. Membrane_insertion_YidC/OxoA_N. [Graphical view]
PANTHER	PTHR12428. Innermemb_insert. 1 hit.
Pfam	PF02096. 60KD_IMP. 1 hit. [Graphical view]
PRINTS	PR00701. 60KDINNERMP. PR01900. YIDCPROTEIN.
TIGRFAMs	TIGR03593. YidC_nterm. 1 hit. TIGR03592. YidC_oxa1_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

OXAA_RICCN

Accession

Primary (citable) accession number: Q92JJ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 21, 2003
Last sequence update:	December 1, 2001
Last modified:	November 3, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)