Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.UniRule annotation

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyciRCON272944:G1FZG-118-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidCUniRule annotation
Alternative name(s):
Foldase YidCUniRule annotation
Membrane integrase YidCUniRule annotation
Membrane protein YidCUniRule annotation
Gene namesi
Name:yidCUniRule annotation
Ordered Locus Names:RC0074
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000000816 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 25HelicalUniRule annotationAdd BLAST21
Transmembranei334 – 354HelicalUniRule annotationAdd BLAST21
Transmembranei357 – 377HelicalUniRule annotationAdd BLAST21
Transmembranei431 – 451HelicalUniRule annotationAdd BLAST21
Transmembranei476 – 496HelicalUniRule annotationAdd BLAST21
Transmembranei522 – 542HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001247491 – 560Membrane protein insertase YidCAdd BLAST560

Interactioni

Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000101821
KOiK03217
OMAiINPVAGC
OrthoDBiPOG091H00BE

Family and domain databases

Gene3Di2.70.98.90, 1 hit
HAMAPiMF_01810 YidC_type1, 1 hit
InterProiView protein in InterPro
IPR019998 Membr_insert_YidC
IPR028055 Membr_insert_YidC/Oxa1_C
IPR028053 Membr_insert_YidC_N
IPR001708 YidC/ALB3/OXA1/COX18
IPR038210 YidC_periplasmic
IPR038221 YidC_periplasmic_sf
PANTHERiPTHR12428 PTHR12428, 1 hit
PfamiView protein in Pfam
PF02096 60KD_IMP, 1 hit
PF14849 YidC_periplas, 1 hit
PRINTSiPR00701 60KDINNERMP
PR01900 YIDCPROTEIN
TIGRFAMsiTIGR03593 yidC_nterm, 1 hit
TIGR03592 yidC_oxa1_cterm, 1 hit

Sequencei

Sequence statusi: Complete.

Q92JJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNNIINLIA AIILSLSIIF GWQYFVVKPE QKKQQQQIAV QKAENLKKQQ
60 70 80 90 100
LKALVEPATG IVVQEESQVQ RIKIESESLT GSISLKGLRF DDLILKKYKQ
110 120 130 140 150
DLSKNSPEVR LFSPANTENA YFAEVGLVSN LSSVKLPNND TIWNSDSEIL
160 170 180 190 200
SPEKPVHLFW VNEDGVKFLV TITVDENYLF TIEQTIVNNS DKELPVQSYG
210 220 230 240 250
LINRKYIAVE KAVNILHQGP IGCIDENLKE YSYDDIKDKK SEKFAASKVD
260 270 280 290 300
WIGITDKYWL SSLIPDKSSN YSSNFNYALK QGTERYQVDF ISPVQIIKPG
310 320 330 340 350
ENFSIKSRIF AGAKKVDLLD KYEKQYDIKL FDRAIDFGWF YIITKPVFYA
360 370 380 390 400
MNFFYGYVGN FGVSILIVTV IIKLLMFTLA NKSYRSMKKM KNLQPEIDRI
410 420 430 440 450
KNLYSDDKAR LNQEIMALYK KEKVNPVAGC LPILVQIPVF FSIYKVLYVT
460 470 480 490 500
IEMRQAPFYG WIKDLSASDP TTIFNLFGLL PFSPPSFLMI GAWPILMAIT
510 520 530 540 550
MFLQQKMSPE PADPMQAQVM KFMPLIFLFM FSSFPVGLLI YWSWNNILSI
560
IQQYYINKFN
Length:560
Mass (Da):64,444
Last modified:December 1, 2001 - v1
Checksum:iB521D15A76053C94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL02612.1
PIRiB97709
RefSeqiWP_010976759.1, NC_003103.1

Genome annotation databases

EnsemblBacteriaiAAL02612; AAL02612; RC0074
GeneIDi928590
KEGGirco:RC0074
PATRICifig|272944.4.peg.87

Similar proteinsi

Entry informationi

Entry nameiYIDC_RICCN
AccessioniPrimary (citable) accession number: Q92JJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: December 1, 2001
Last modified: April 25, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health