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Q92JH7

- KDSA_RICCN

UniProt

Q92JH7 - KDSA_RICCN

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Protein
2-dehydro-3-deoxyphosphooctonate aldolase
Gene
kdsA, RC0090
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 3-deoxy-8-phosphooctulonate synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00030.
UPA00357; UER00474.

Names & Taxonomyi

Protein namesi
Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolase (EC:2.5.1.55)
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase
KDO-8-phosphate synthase
Short name:
KDO 8-P synthase
Short name:
KDOPS
Phospho-2-dehydro-3-deoxyoctonate aldolase
Gene namesi
Name:kdsA
Ordered Locus Names:RC0090
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2742742-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation
PRO_0000187159Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0090.

Structurei

3D structure databases

ProteinModelPortaliQ92JH7.
SMRiQ92JH7. Positions 17-271.

Family & Domainsi

Sequence similaritiesi

Belongs to the KdsA family.

Phylogenomic databases

eggNOGiCOG2877.
HOGENOMiHOG000023021.
KOiK01627.
OMAiMESREHA.
OrthoDBiEOG680X4R.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00056. KDO8P_synth.
InterProiIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
PANTHERiPTHR21057:SF2. PTHR21057:SF2. 1 hit.
PfamiPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92JH7-1 [UniParc]FASTAAdd to Basket

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MQKVVKLNNI KIGNDLPFVL ITGPCQIEGK DHALFMAEKL VKLTSKLEIP    50
FIYKSSFDKA NRTSVHGIRG VGIEKGLEIL SKVKSEFDCP IVTDVHSESQ 100
CTETAEVADI LQIPAFLCRQ TDLLQAAAKT GKIVKVKKGQ FLAPWDMKNV 150
QTKLEAFGVK DILFTERGAC FGYNNLVSDM RSLAIMAELN VPVVFDATHS 200
VQQPGGLGGS TGGERKYVEL LAKAATSVGI AGIYMEVHQD PDNAPSDGPC 250
MMKLDNLESI LIKLKKYDKI TKEK 274
Length:274
Mass (Da):30,030
Last modified:December 1, 2001 - v1
Checksum:i8DD10B8B8FFDC735
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL02628.1.
PIRiB97711.
RefSeqiNP_359727.1. NC_003103.1.
WP_010976774.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02628; AAL02628; RC0090.
GeneIDi928110.
KEGGirco:RC0090.
PATRICi17887286. VBIRicCon45613_0107.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL02628.1 .
PIRi B97711.
RefSeqi NP_359727.1. NC_003103.1.
WP_010976774.1. NC_003103.1.

3D structure databases

ProteinModelPortali Q92JH7.
SMRi Q92JH7. Positions 17-271.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272944.RC0090.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL02628 ; AAL02628 ; RC0090 .
GeneIDi 928110.
KEGGi rco:RC0090.
PATRICi 17887286. VBIRicCon45613_0107.

Phylogenomic databases

eggNOGi COG2877.
HOGENOMi HOG000023021.
KOi K01627.
OMAi MESREHA.
OrthoDBi EOG680X4R.

Enzyme and pathway databases

UniPathwayi UPA00030 .
UPA00357 ; UER00474 .

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00056. KDO8P_synth.
InterProi IPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view ]
PANTHERi PTHR21057:SF2. PTHR21057:SF2. 1 hit.
Pfami PF00793. DAHP_synth_1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01362. KDO8P_synth. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiKDSA_RICCN
AccessioniPrimary (citable) accession number: Q92JH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: December 1, 2001
Last modified: September 3, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia conorii
    (strain Malish 7): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi