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Q92JH7

- KDSA_RICCN

UniProt

Q92JH7 - KDSA_RICCN

Protein

2-dehydro-3-deoxyphosphooctonate aldolase

Gene

kdsA

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 3-deoxy-8-phosphooctulonate synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00030.
    UPA00357; UER00474.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation (EC:2.5.1.55UniRule annotation)
    Alternative name(s):
    3-deoxy-D-manno-octulosonic acid 8-phosphate synthaseUniRule annotation
    KDO-8-phosphate synthaseUniRule annotation
    Short name:
    KDO 8-P synthaseUniRule annotation
    Short name:
    KDOPSUniRule annotation
    Phospho-2-dehydro-3-deoxyoctonate aldolaseUniRule annotation
    Gene namesi
    Name:kdsAUniRule annotation
    Ordered Locus Names:RC0090
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2742742-dehydro-3-deoxyphosphooctonate aldolasePRO_0000187159Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC0090.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92JH7.
    SMRiQ92JH7. Positions 17-271.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KdsA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2877.
    HOGENOMiHOG000023021.
    KOiK01627.
    OMAiMESREHA.
    OrthoDBiEOG680X4R.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00056. KDO8P_synth.
    InterProiIPR013785. Aldolase_TIM.
    IPR006218. DAHP1/KDSA.
    IPR006269. KDO8P_synthase.
    [Graphical view]
    PANTHERiPTHR21057:SF2. PTHR21057:SF2. 1 hit.
    PfamiPF00793. DAHP_synth_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q92JH7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQKVVKLNNI KIGNDLPFVL ITGPCQIEGK DHALFMAEKL VKLTSKLEIP    50
    FIYKSSFDKA NRTSVHGIRG VGIEKGLEIL SKVKSEFDCP IVTDVHSESQ 100
    CTETAEVADI LQIPAFLCRQ TDLLQAAAKT GKIVKVKKGQ FLAPWDMKNV 150
    QTKLEAFGVK DILFTERGAC FGYNNLVSDM RSLAIMAELN VPVVFDATHS 200
    VQQPGGLGGS TGGERKYVEL LAKAATSVGI AGIYMEVHQD PDNAPSDGPC 250
    MMKLDNLESI LIKLKKYDKI TKEK 274
    Length:274
    Mass (Da):30,030
    Last modified:December 1, 2001 - v1
    Checksum:i8DD10B8B8FFDC735
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02628.1.
    PIRiB97711.
    RefSeqiNP_359727.1. NC_003103.1.
    WP_010976774.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02628; AAL02628; RC0090.
    GeneIDi928110.
    KEGGirco:RC0090.
    PATRICi17887286. VBIRicCon45613_0107.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02628.1 .
    PIRi B97711.
    RefSeqi NP_359727.1. NC_003103.1.
    WP_010976774.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92JH7.
    SMRi Q92JH7. Positions 17-271.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0090.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02628 ; AAL02628 ; RC0090 .
    GeneIDi 928110.
    KEGGi rco:RC0090.
    PATRICi 17887286. VBIRicCon45613_0107.

    Phylogenomic databases

    eggNOGi COG2877.
    HOGENOMi HOG000023021.
    KOi K01627.
    OMAi MESREHA.
    OrthoDBi EOG680X4R.

    Enzyme and pathway databases

    UniPathwayi UPA00030 .
    UPA00357 ; UER00474 .

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00056. KDO8P_synth.
    InterProi IPR013785. Aldolase_TIM.
    IPR006218. DAHP1/KDSA.
    IPR006269. KDO8P_synthase.
    [Graphical view ]
    PANTHERi PTHR21057:SF2. PTHR21057:SF2. 1 hit.
    Pfami PF00793. DAHP_synth_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01362. KDO8P_synth. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiKDSA_RICCN
    AccessioniPrimary (citable) accession number: Q92JH7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 10, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia conorii
      (strain Malish 7): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3