Reviewed, UniProtKB/Swiss-Prot Q92JG1 (SAM_RICCN)

Names and origin

Protein names

Recommended name:
    S-adenosylmethionine uptake transporter

Gene names

Name:	sam
Ordered Locus Names:	RC0106

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transports S-adenosylmethionine By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (TC 2.A.7.3) family. [View classification]

Ontologies

Keywords
Biological process	Amino-acid transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	amino acid transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 294	294	S-adenosylmethionine uptake transporter		PRO_0000280995
Regions
	Transmembrane	8 – 28	21	Potential
	Transmembrane	41 – 61	21	Potential
	Transmembrane	74 – 91	18	Potential
	Transmembrane	98 – 118	21	Potential
	Transmembrane	121 – 141	21	Potential
	Transmembrane	148 – 168	21	Potential
	Transmembrane	177 – 197	21	Potential
	Transmembrane	207 – 227	21	Potential
	Transmembrane	237 – 257	21	Potential
	Transmembrane	260 – 280	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92JG1-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 48DDFD6B00D28104	FASTA	294	33,071
	10 20 30 40 50 60 MNDALKTYLT GIGWFLLSLV SSSANDVISK YLGTRLHSFE VAFFRFFFSS IVLLPFVVYY 70 80 90 100 110 120 GKNTLKTSRP FVHILRGLLL FFGMTSWTYG LTIAPVTTAT VVSFSIPLFT LILAVFFLNE 130 140 150 160 170 180 NIIWPRWVVT VVGFIGLVVT LKPHAEDFNP EILYFVLAAI SFAMLDIINK KFVIKESMIS 190 200 210 220 230 240 MLFYSAIVTA IVSLPVASQY WLTPSSFELA LLFVLGSSGS LILFFLLKAF SMVDATATAP 250 260 270 280 290 YRYLELVISV IAAYFIFNEF PDKSTLHGAV IIIPTTLFII YSEKKAMNRK HESQ

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL02644.1.
PIR	B97713.
RefSeq	NP_359743.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	928090.
GenomeReviews	Gene locus RC0106 in contig AE006914_GR.
KEGG	rco:RC0106.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q92JG1.
OMA	PVASQYW
Enzyme and pathway databases
BioCyc	RCON272944:RC0106-MON.
Family and domain databases
InterPro	IPR000620. DUF6_TM. [Graphical view]
Pfam	PF00892. DUF6. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SAM_RICCN

Accession

Primary (citable) accession number: Q92JG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	December 1, 2001
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)