Reviewed, UniProtKB/Swiss-Prot Q92JF7 (SCA2_RICCN)

Names and origin

Protein names

Recommended name:
    Putative surface cell antigen sca2

Gene names

Name:	sca2
Ordered Locus Names:	RC0110

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	1795 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell outer membrane By similarity.
Sequence similarities	Contains 1 autotransporter (TC 1.B.12) domain. [View classification]

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 33	33	Potential
	Chain	34 – 1795	1762	Putative surface cell antigen sca2		PRO_0000262569
Regions
	Domain	1516 – 1795	280	Autotransporter
	Compositional bias	672 – 699	28	Pro-rich
	Compositional bias	1077 – 1087	11	Pro-rich

Sequences

	Sequence		Length	Mass (Da)
	Q92JF7-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: BC8AE9FDC2D03A16	FASTA	1,795	203,997
	10 20 30 40 50 60 MNLQNSHSKK YVLTFFMSTC LLTSSFLSTS ARAASFKDLV SKTPAWEKHN STQQQNIWKD 70 80 90 100 110 120 LTPNEKIKKW QEAALVPSFT QAQNDLGIKY KETDLSSFLD NTRHKARQAR AEILLYIERV 130 140 150 160 170 180 KQQDFDTKKQ AYINQGVVPT DIEAATNLGI SYDPSKIDNN VEHDQKVRRA EKDKKAVIEL 190 200 210 220 230 240 YVSSINRGIK YKHYVDNDII PEIQEVRTAL NMNKDDAQSF VASIRTEIME NAKGQYIADS 250 260 270 280 290 300 HIPTEKELKK KFGISRDDNR DGYIKSIRLK VMDKEKPQYI ADSHIPTEKE LEQKFGADKG 310 320 330 340 350 360 EATNYIASIA TQMMLDKKSY YIDNNIIPNA DELMNEFKIG PVKATSYINQ IRAGIEANQF 370 380 390 400 410 420 LNNNDTTKPS TGRSQKKSGS KNDHWYMSNQ SINNTGTSAR IVTGREKKQR YFFDPISTFK 430 440 450 460 470 480 TYFNTKASKG NLTQSQHNIN RIIQQEENIE EFKNLIKTDP IAALTLQVDS SYKQEAVTTI 490 500 510 520 530 540 LSDFNDDTIQ RVLFSNDKGK LDFNTNIDVK NRPILQELLE NSSSEEKTKF AERIQDYATR 550 560 570 580 590 600 NISNSQFEEK ARLDLIKLAA SKDKSSVENF LTLQLELKNR MQPYVVNSVY ILTPEIVKEI 610 620 630 640 650 660 NIELKNKGLI RDSLTKDYMI KLAKEVNNHT LNSVIKVILS DSKILSNETN KILGLAVSNN 670 680 690 700 710 720 ANNLEQTQSG IPNPPPLPLN GGIPNPPPLP LNGSMPPPPL HSQGFSSNSK HFDLNQLQTE 730 740 750 760 770 780 YPHIHSLYVQ FTHNTTVQSK APLQPTASSA TSTGRSTPET AYAKLYAEYR TETGGTKAND 790 800 810 820 830 840 LQDQLIKRQA DLTNVIRQIL TESYANQGAD EKTLLNLFSI STPEIAEKAK EAFNTLAQDQ 850 860 870 880 890 900 YIKDITVNGK KTITSEEIIK NLFNEDTDDA IKRILLSSCK ISEELKRPIK LEFNKSELIR 910 920 930 940 950 960 ELQGKQNPFK QLEFAYINTK NFDQDIFGNR IDELINNPNI LTIVQQATFL TKEDTNLRKT 970 980 990 1000 1010 1020 INSDQAQAKL DDLRTAILST IKIEELITAN LPQHDFIAIV KEKDPELLKE FLKATTLTVT 1030 1040 1050 1060 1070 1080 GNNNLDQLRL ALPSFTGMSN EQIRILSNKL KMSIILKALK ECSQEKATQY IHTGNMPPPP 1090 1100 1110 1120 1130 1140 PPPPPLPDSQ DLELAYLKSL GITKANTSTF KTTPKTYHFS SDIALRYKEF TLSGQKSAGY 1150 1160 1170 1180 1190 1200 KAKYSDADLL KKAIVESVAF EHSKNLSKAH QNNKYFEQIQ KAVNTMYSSF IGHRTELEQK 1210 1220 1230 1240 1250 1260 IHNIYTSKLL ELTKDKEFIK YVEDNIILNK KLTKAFTSAD SDFIDSRTEL EQKIHNIYIQ 1270 1280 1290 1300 1310 1320 QLTKYPEEEV KEAFNTASLD FIGPRTEIGQ EVHNIYKSQL LELTKDTELC LFTQQVLAEA 1330 1340 1350 1360 1370 1380 TELEQKYGSD IQSENSNNEK KVERLDQEKL QLFKQENEAT NDESSTKDDT QPEDSNKKSE 1390 1400 1410 1420 1430 1440 QSDSKTALSP RLLSSNDSKN DKSSDDKKSL LALRSSDEDD TGYATDEEEL EESNSTTDEE 1450 1460 1470 1480 1490 1500 LKKDVVLESE DEAIDVSFKT EAITEQDEVT QRQQVSDDTS GKVAILVQAT STLHKPVHYN 1510 1520 1530 1540 1550 1560 INDRLTVAAI GAGDEETSIN RGVWISGLYG INKQRIWKNI PKYQNRTTGI TIGTDAEFIN 1570 1580 1590 1600 1610 1620 SHDVIGIAYS RLESQIKYNK KLGKTTVNGH LLSIYSLKEL IKGFSLQTIT SYGHNYIKNR 1630 1640 1650 1660 1670 1680 SKNINNIIGK YQNNSLSFQT LLNYKYRTKY DLHFIPNIGF QYDYSRASNY KEYNVDIENL 1690 1700 1710 1720 1730 1740 MIQKKSNQLF ESSLGGKIVF KPIVTTNNIV LTPSLYGNIE HHFNNKNTKV NAKATFKGQT 1750 1760 1770 1780 1790 LQETIITLKQ PKLGYNIGSN ILMSRKNINV LLEYNYYTHR KYQSHQGLIK LKVNL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.
[2]	"Phylogenetic study of Rickettsia species using sequences of the autotransporter protein-encoding gene sca2." Ngwamidiba M., Blanc G., Ogata H., Raoult D., Fournier P.-E. Ann. N. Y. Acad. Sci. 1063:94-99(2005) [PubMed: 16481498] [Abstract] Cited for: IDENTIFICATION AT TRANSCRIPTIONAL LEVEL. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL02648.1.
PIR	F97713.
RefSeq	NP_359747.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	928084.
GenomeReviews	Gene locus RC0110 in contig AE006914_GR.
KEGG	rco:RC0110.
NMPDR	fig|272944.1.peg.110.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q92JF7.
OMA	FIGPRTE
Enzyme and pathway databases
BioCyc	RCON272944:RC0110-MON.
Family and domain databases
InterPro	IPR005546. Auto_transptbeta. IPR015425. FH2_actin_bd. IPR006315. OM_autotransptr_brl. [Graphical view]
Pfam	PF03797. Autotransporter. 1 hit. [Graphical view]
SMART	SM00869. Autotransporter. 1 hit. [Graphical view]
TIGRFAMs	TIGR01414. autotrans_barl. 1 hit.
PROSITE	PS51208. AUTOTRANSPORTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCA2_RICCN

Accession

Primary (citable) accession number: Q92JF7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	December 1, 2001
Last modified:	November 24, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)