Q92JF4 (EFTS_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Ts
Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	RC0113

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. HAMAP MF_00050
Subcellular location	Cytoplasm HAMAP MF_00050.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Elongation factor Ts HAMAP MF_00050		PRO_0000161184
Regions
	Region	82 – 85	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q92JF4 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 88DEE8672403FDBB	FASTA	309	33,747
	10 20 30 40 50 60 MSEINISAAA VKELREKTGA GMMDCKKALI ETSGNFEEAI DFLRKKGLAA AAKKAGRIAS 70 80 90 100 110 120 EGLTAAKVDG LTGVVIEVNS ETDFVARNEQ FQDLVKDIAN LAVIAKTIDT LKTFKMQSGK 130 140 150 160 170 180 SVEEEIIENI ATIGENLTLR RMDILEISEG AIGSYVHNEV VPNLGKISVL VGLASNAKDK 190 200 210 220 230 240 AKLEALAKQI AVHVAGNNPQ SIDDSSLDQA LVERERKVFF EKSKEEGKPD NIIAKMVEGR 250 260 270 280 290 300 IRKFFSEVVL LQQNFLFEPK LTVAEVIKNA EKELGAEIKI AKFIRYELGE GIEHEEKNFA DEVAAITQG

References

[1]	"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL02651.1.
PIR	A97714.
RefSeq	NP_359750.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92JF4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	928081.
GenomeReviews	Gene locus RC0113 in contig AE006914_GR.
KEGG	rco:RC0113.
PATRIC	17887342. VBIRicCon45613_0134.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YLHGTRI.
ProtClustDB	PRK09377.
Enzyme and pathway databases
BioCyc	RCON272944:RC0113-MONOMER.
Family and domain databases
HAMAP	MF_00050. EF_Ts. [Tree]
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Gene3D	G3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 3 hits.
KO	K02357.
PANTHER	PTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF54713. EF_TS. 1 hit. SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00116. Tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_RICCN

Accession

Primary (citable) accession number: Q92JF4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2002
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program