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Q92JE7 (AAT_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aspartate aminotransferase

Short name=AspAT
EC=2.6.1.1
Alternative name(s):
Transaminase A
Gene names
Name:aatA
Synonyms:aspC
Ordered Locus Names:RC0120
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactor

Pyridoxal phosphate By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Aspartate aminotransferase
PRO_0000123850

Sites

Binding site391Aspartate; via amide nitrogen By similarity
Binding site1251Aspartate By similarity
Binding site1751Aspartate By similarity
Binding site3751Aspartate By similarity

Amino acid modifications

Modified residue2391N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92JE7 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 580494ECD865CF36

FASTA40144,576
        10         20         30         40         50         60 
MSIISTRLSS IKPSPTLAVV KKTLELKKAG VDIITLGAGE PDFDTPDNIK EGAIKAIKDG 

        70         80         90        100        110        120 
FTKYTNVEGM PLLKQAIKDK FKRENNIDYE LDEIIVSTGG KQVIYNLFMA SLDQGDEVII 

       130        140        150        160        170        180 
PAPYWVSYPD MVALSTGTPV FVNCGIENNF KLSAEALERS ITDKTKWLII NSPSNPTGAS 

       190        200        210        220        230        240 
YNFEELENIA KVLRKYSHVN VMSDDIYEHI TFDDFKFYTL AQIAPDLKKR IFTVNGVSKA 

       250        260        270        280        290        300 
YSMTGWRIGY GAGSKTLIKA MTIIQSQSTS NPCSISQMAA IEALNGPQDY IKPNALNCQK 

       310        320        330        340        350        360 
KRDLALSILK RVKYFECYKP EGAFYLFVKC DKIFGHKTKS GTIIANSNDF AEYLLEEAKV 

       370        380        390        400 
AVVPGIAFGL EGYFRISYAT SMEELEKACI RIEKTIDVIP A 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL02658.1.
PIRH97714.
RefSeqNP_359757.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92JE7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0120.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL02658; AAL02658; RC0120.
GeneID928075.
KEGGrco:RC0120.
PATRIC17887359. VBIRicCon45613_0142.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0436.
HOGENOMHOG000223062.
KOK00812.
OMADFNTPEF.
OrthoDBEOG6RRKNS.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAAT_RICCN
AccessionPrimary (citable) accession number: Q92JE7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names