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Protein

Aspartate aminotransferase

Gene

aatA

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei39Aspartate; via amide nitrogenBy similarity1
Binding sitei125AspartateBy similarity1
Binding sitei175AspartateBy similarity1
Binding sitei375AspartateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciRCON272944:G1FZG-190-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferase (EC:2.6.1.1)
Short name:
AspAT
Alternative name(s):
Transaminase A
Gene namesi
Name:aatA
Synonyms:aspC
Ordered Locus Names:RC0120
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000000816 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001238501 – 401Aspartate aminotransferaseAdd BLAST401

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei239N6-(pyridoxal phosphate)lysineBy similarity1

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ92JE7
SMRiQ92JE7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000223062
KOiK00812
OMAiYWTTYPE
OrthoDBiPOG091H00QO

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR004839 Aminotransferase_I/II
IPR004838 NHTrfase_class1_PyrdxlP-BS
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00105 AA_TRANSFER_CLASS_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q92JE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIISTRLSS IKPSPTLAVV KKTLELKKAG VDIITLGAGE PDFDTPDNIK
60 70 80 90 100
EGAIKAIKDG FTKYTNVEGM PLLKQAIKDK FKRENNIDYE LDEIIVSTGG
110 120 130 140 150
KQVIYNLFMA SLDQGDEVII PAPYWVSYPD MVALSTGTPV FVNCGIENNF
160 170 180 190 200
KLSAEALERS ITDKTKWLII NSPSNPTGAS YNFEELENIA KVLRKYSHVN
210 220 230 240 250
VMSDDIYEHI TFDDFKFYTL AQIAPDLKKR IFTVNGVSKA YSMTGWRIGY
260 270 280 290 300
GAGSKTLIKA MTIIQSQSTS NPCSISQMAA IEALNGPQDY IKPNALNCQK
310 320 330 340 350
KRDLALSILK RVKYFECYKP EGAFYLFVKC DKIFGHKTKS GTIIANSNDF
360 370 380 390 400
AEYLLEEAKV AVVPGIAFGL EGYFRISYAT SMEELEKACI RIEKTIDVIP

A
Length:401
Mass (Da):44,576
Last modified:December 1, 2001 - v1
Checksum:i580494ECD865CF36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL02658.1
PIRiH97714
RefSeqiWP_010976800.1, NC_003103.1

Genome annotation databases

EnsemblBacteriaiAAL02658; AAL02658; RC0120
GeneIDi928075
KEGGirco:RC0120
PATRICifig|272944.4.peg.142

Similar proteinsi

Entry informationi

Entry nameiAAT_RICCN
AccessioniPrimary (citable) accession number: Q92JE7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: December 1, 2001
Last modified: April 25, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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