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Q92JE7

- AAT_RICCN

UniProt

Q92JE7 - AAT_RICCN

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Protein

Aspartate aminotransferase

Gene

aatA

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391Aspartate; via amide nitrogenBy similarity
Binding sitei125 – 1251AspartateBy similarity
Binding sitei175 – 1751AspartateBy similarity
Binding sitei375 – 3751AspartateBy similarity

GO - Molecular functioni

  1. L-aspartate:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferase (EC:2.6.1.1)
Short name:
AspAT
Alternative name(s):
Transaminase A
Gene namesi
Name:aatA
Synonyms:aspC
Ordered Locus Names:RC0120
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Aspartate aminotransferasePRO_0000123850Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei239 – 2391N6-(pyridoxal phosphate)lysineBy similarity

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi272944.RC0120.

Structurei

3D structure databases

ProteinModelPortaliQ92JE7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0436.
HOGENOMiHOG000223062.
KOiK00812.
OMAiDFNTPEF.
OrthoDBiEOG6RRKNS.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92JE7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIISTRLSS IKPSPTLAVV KKTLELKKAG VDIITLGAGE PDFDTPDNIK
60 70 80 90 100
EGAIKAIKDG FTKYTNVEGM PLLKQAIKDK FKRENNIDYE LDEIIVSTGG
110 120 130 140 150
KQVIYNLFMA SLDQGDEVII PAPYWVSYPD MVALSTGTPV FVNCGIENNF
160 170 180 190 200
KLSAEALERS ITDKTKWLII NSPSNPTGAS YNFEELENIA KVLRKYSHVN
210 220 230 240 250
VMSDDIYEHI TFDDFKFYTL AQIAPDLKKR IFTVNGVSKA YSMTGWRIGY
260 270 280 290 300
GAGSKTLIKA MTIIQSQSTS NPCSISQMAA IEALNGPQDY IKPNALNCQK
310 320 330 340 350
KRDLALSILK RVKYFECYKP EGAFYLFVKC DKIFGHKTKS GTIIANSNDF
360 370 380 390 400
AEYLLEEAKV AVVPGIAFGL EGYFRISYAT SMEELEKACI RIEKTIDVIP

A
Length:401
Mass (Da):44,576
Last modified:December 1, 2001 - v1
Checksum:i580494ECD865CF36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02658.1.
PIRiH97714.
RefSeqiNP_359757.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02658; AAL02658; RC0120.
GeneIDi928075.
KEGGirco:RC0120.
PATRICi17887359. VBIRicCon45613_0142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02658.1 .
PIRi H97714.
RefSeqi NP_359757.1. NC_003103.1.

3D structure databases

ProteinModelPortali Q92JE7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0120.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL02658 ; AAL02658 ; RC0120 .
GeneIDi 928075.
KEGGi rco:RC0120.
PATRICi 17887359. VBIRicCon45613_0142.

Phylogenomic databases

eggNOGi COG0436.
HOGENOMi HOG000223062.
KOi K00812.
OMAi DFNTPEF.
OrthoDBi EOG6RRKNS.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
Pfami PF00155. Aminotran_1_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
PROSITEi PS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiAAT_RICCN
AccessioniPrimary (citable) accession number: Q92JE7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: December 1, 2001
Last modified: November 26, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3