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Protein

Uncharacterized lipoprotein RC0146

Gene

RC0146

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

  1. protein secretion by the type IV secretion system Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized lipoprotein RC0146
Gene namesi
Ordered Locus Names:RC0146
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Cell membrane PROSITE-ProRule annotation; Multi-pass membrane protein Curated. Cell membrane PROSITE-ProRule annotation; Lipid-anchor PROSITE-ProRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei289 – 30921HelicalSequence AnalysisAdd
BLAST
Transmembranei393 – 41321HelicalSequence AnalysisAdd
BLAST
Transmembranei422 – 44221HelicalSequence AnalysisAdd
BLAST
Transmembranei457 – 47721HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818PROSITE-ProRule annotationAdd
BLAST
Chaini19 – 11531135Uncharacterized lipoprotein RC0146PRO_0000269910Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi19 – 191N-palmitoyl cysteinePROSITE-ProRule annotation
Lipidationi19 – 191S-diacylglycerol cysteinePROSITE-ProRule annotation

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0146.

Structurei

3D structure databases

ProteinModelPortaliQ92JC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrbL/VirB6 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3704.
HOGENOMiHOG000010636.
KOiK03201.
OMAiECIDERY.
OrthoDBiEOG64R60Z.

Family and domain databases

InterProiIPR007688. Conjugal_tfr_TrbL/VirB6.
[Graphical view]
PfamiPF04610. TrbL. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q92JC1-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MNKNIFITLL ISLLLLSGCT GDTCIDPDDF GFIKFNVSAR YDPEEITSRQ
60 70 80 90 100
EGNQVAPWRD SAYKVNGYPL TIMVRPWSYI LGDKNTSGQL SAWCPWYGQK
110 120 130 140 150
NNTTTLAAFC VKLQPCTFWD NTRLDMCTPN PANQNDAMIS NAPCIMTNGV
160 170 180 190 200
GLYFLIAAKN TDPNISPDSQ SKPQGITQHL GEELTSGYEF YSTSSTGQFS
210 220 230 240 250
KAGGINYQYK GEDKSKYAQS PLYFKIIDKF YNDNSGQYRL VIKSGVTDTR
260 270 280 290 300
ADPLQFLTDL IKGVLFGKDG IIKKTYQQII DTSGYRMSVS AILTLYIMFT
310 320 330 340 350
GFSFLIGNIN LTHVELIVRI LKVSIVSILL STDKAWTFFH DYLFVFFIDG
360 370 380 390 400
VQQILQIINE ASATGPGSQS LLGLLISPQT LSKLFSLLFV DWLGFIYIIL
410 420 430 440 450
YLIALYFIFF LIFKATIIYL TALITIGMII IMGPIFICFM LFNITRSLFE
460 470 480 490 500
NWLRQLISYA LQPIILFTGI AFISMIIRTE IYSTLGFAVC KHDFPNLGPI
510 520 530 540 550
NEIFGSFLED IDPSLGHSIF YWWFPVPMKG GINNFHKANI LVPKDHIVVD
560 570 580 590 600
DSCKNDPDKC KHCAAYECID ERYIELPFLD LVKDAKRISN FINGKFVQLD
610 620 630 640 650
GILLIFVSIY LLSKFNDTAI STAQFIAGTS GNLTEIQKVN QQSYESAAKQ
660 670 680 690 700
MNRPLNYVAK TVSAPVTSRV SAGKEQVRMF FAEKFENMMM GRLEKQALGS
710 720 730 740 750
SANKTVQNEV KRKYGIDSKD VKMNAITDYE NGIAGLLKNL PKGNELKAKE
760 770 780 790 800
LSQMKFTQLR DKIAANKYGV KDYAALSKEQ KAELDKSLKD ANLRELASDA
810 820 830 840 850
NFTRDYQDAY KNAHQEMSGR GVGLFGKNIG VLRSWQEIKH RVDTKRKLKE
860 870 880 890 900
EKRVGIGEKI YAGYTGIKRG VLTAIVGKDL RDAYEGNLTS AEWHDFEYND
910 920 930 940 950
PRLRTYSEKL KDDEKAREHE ELQMHINKEA LAAQADILSP EYLARLEKAG
960 970 980 990 1000
RHSDVEYYQE LAQRKLIHEV HGRLFEEGEP VMMGDRFMRE KATDSQMRDM
1010 1020 1030 1040 1050
IDNAHRKHAE FIDGDRYIRR QEHYDIMHEK AQENLEQTYK ELKDHFKRDD
1060 1070 1080 1090 1100
IKIEEMPALI AQKVKDTAEG AEIDQKITEE LNNFNADVKN YEYSTEVLNK
1110 1120 1130 1140 1150
IEDRKQAITD EVNAQIDKIN KYRENAKMQT YVKPIVNEGR KLRKLEDHLR

NMK
Length:1,153
Mass (Da):131,619
Last modified:December 1, 2001 - v1
Checksum:iA869C596FE0C29B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02684.1.
PIRiB97718.
RefSeqiNP_359783.1. NC_003103.1.
WP_010976823.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02684; AAL02684; RC0146.
GeneIDi928043.
KEGGirco:RC0146.
PATRICi17887417. VBIRicCon45613_0170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02684.1.
PIRiB97718.
RefSeqiNP_359783.1. NC_003103.1.
WP_010976823.1. NC_003103.1.

3D structure databases

ProteinModelPortaliQ92JC1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272944.RC0146.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL02684; AAL02684; RC0146.
GeneIDi928043.
KEGGirco:RC0146.
PATRICi17887417. VBIRicCon45613_0170.

Phylogenomic databases

eggNOGiCOG3704.
HOGENOMiHOG000010636.
KOiK03201.
OMAiECIDERY.
OrthoDBiEOG64R60Z.

Family and domain databases

InterProiIPR007688. Conjugal_tfr_TrbL/VirB6.
[Graphical view]
PfamiPF04610. TrbL. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiY146_RICCN
AccessioniPrimary (citable) accession number: Q92JC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: December 1, 2001
Last modified: January 7, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.