Q92JB3 (SECF_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein translocase subunit SecF

Gene names

Name:	secF
Ordered Locus Names:	RC0154

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA By similarity. HAMAP-Rule MF_01464
Subunit structure	Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01464.
Sequence similarities	Belongs to the SecD/SecF family. SecF subfamily.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	intracellular protein transmembrane transport Inferred from electronic annotation. Source: HAMAP protein targeting Inferred from electronic annotation. Source: HAMAP protein transport by the Sec complex Inferred from electronic annotation. Source: HAMAP
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	P-P-bond-hydrolysis-driven protein transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 308	308	Protein translocase subunit SecF HAMAP-Rule MF_01464		PRO_0000272638
Regions
	Transmembrane	28 – 48	21	Helical; Potential
	Transmembrane	140 – 160	21	Helical; Potential
	Transmembrane	164 – 184	21	Helical; Potential
	Transmembrane	194 – 214	21	Helical; Potential
	Transmembrane	246 – 266	21	Helical; Potential
	Transmembrane	272 – 292	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92JB3 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: ACC302C07B48D720	FASTA	308	35,033
	10 20 30 40 50 60 MQIYPLRLLP NKIDFDFMNF KKVSYTFSII LSLISFIWIG IYKFNFGIDF AGGIVIEVRL 70 80 90 100 110 120 DQAPDLPKMR GVLGKLGIGE VVLQNFGSER DLSIRFGSSS EENLMKNIEL IKGFLQSNFP 130 140 150 160 170 180 YKFEYRKVDF VGPQVGRQLI EAGAMAMLFS FLAIMVYIWV RFEWYFGLGI LIALVHDVIL 190 200 210 220 230 240 ALGFMSMTKL DFNLSTIAAV LTIIGYSVND SVVIYDRIRE NLRKYHKKNI TEIINLSINE 250 260 270 280 290 300 TLSRTILTVI TTLLANLALI LFGGEAIRSF SVLVFFGIIA GTYSSIFISA PILTMFVNRK FNKKVIER

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL02692.1.
PIR	B97719.
RefSeq	NP_359791.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92JB3.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC0154.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL02692; AAL02692; RC0154.
GeneID	928040.
KEGG	rco:RC0154.
PATRIC	17887441. VBIRicCon45613_0182.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0341.
HOGENOM	HOG000245916.
KO	K03074.
OMA	GLKREHM.
ProtClustDB	PRK13022.
Family and domain databases
HAMAP	MF_01464_B. SecF_B.
InterPro	IPR022813. SecD/SecF. IPR022645. SecD/SecF_bac. IPR022646. SecD/SecF_CS. IPR005665. SecF_bac. IPR000731. SSD. [Graphical view]
Pfam	PF07549. Sec_GG. 1 hit. PF02355. SecD_SecF. 1 hit. [Graphical view]
PRINTS	PR01755. SECFTRNLCASE.
TIGRFAMs	TIGR00916. 2A0604s01. 1 hit. TIGR00966. 3a0501s07. 1 hit.
PROSITE	PS50156. SSD. 1 hit. Uncertain. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SECF_RICCN

Accession

Primary (citable) accession number: Q92JB3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program