Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q92JA9

- ERA_RICCN

UniProt

Q92JA9 - ERA_RICCN

Protein

GTPase Era

Gene

era

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi59 – 668GTPUniRule annotation
    Nucleotide bindingi106 – 1105GTPUniRule annotation
    Nucleotide bindingi168 – 1714GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-HAMAP
    3. small ribosomal subunit rRNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. ribosomal small subunit biogenesis Source: UniProtKB-HAMAP

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding, RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTPase EraUniRule annotation
    Gene namesi
    Name:eraUniRule annotation
    Ordered Locus Names:RC0158
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm. Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Cytoplasm, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 339339GTPase EraPRO_0000180042Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi272944.RC0158.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92JA9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 4845RPE1 insertAdd
    BLAST
    Domaini51 – 220170Era-type GAdd
    BLAST
    Domaini248 – 32578KH type-2UniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.UniRule annotation
    Contains 1 KH type-2 domain.UniRule annotation
    Contains 1 RPE1 insert domain.Curated

    Phylogenomic databases

    eggNOGiCOG1159.
    HOGENOMiHOG000245597.
    KOiK03595.
    OMAiHDNAQIV.
    OrthoDBiEOG68DD1Q.

    Family and domain databases

    Gene3Di3.30.300.20. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00367. GTPase_Era.
    InterProiIPR005662. GTP-bd_Era.
    IPR006073. GTP_binding_domain.
    IPR015946. KH_dom-like_a/b.
    IPR004044. KH_dom_type_2.
    IPR009019. KH_prok-type.
    IPR027417. P-loop_NTPase.
    IPR005728. Rickett_RPE.
    IPR005225. Small_GTP-bd_dom.
    [Graphical view]
    PfamiPF07650. KH_2. 1 hit.
    PF01926. MMR_HSR1. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF54814. SSF54814. 1 hit.
    TIGRFAMsiTIGR00436. era. 1 hit.
    TIGR01045. RPE1. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51713. G_ERA. 1 hit.
    PS50823. KH_TYPE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92JA9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNRHLAKFA YREEFKGDTE ALAAAVREDA STGSTSQLPL EVQFGKMSNQ    50
    KTVSVCIIGR PNSGKSTLLN RIIGEKLSIV TPKVQTTRSI ITGIITLKDT 100
    QVILYDTPGI FEPKGSLEKA MVRCAWSSLH SADLVLLIID SLKSFDDITH 150
    NIVDKLRSLN IVPIFLLNKI DIESKYLNDI KAFLTENHPD SLLFPISALS 200
    GKNIDGLLEY ITSKAKISPW LYAEDDITDL PMRFIAAEIT REQLFLNLQK 250
    ELPYKLTVQT EKWEDLKDKS VKINQVIVVS RESYKTIILG KNGSKIKEIG 300
    AKSRMQMERF FGFPVHLFLF VKVRELWENN QEFYQYMKI 339
    Length:339
    Mass (Da):38,582
    Last modified:December 1, 2001 - v1
    Checksum:i9378BCB362B8A62D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02696.1.
    PIRiF97719.
    RefSeqiNP_359795.1. NC_003103.1.
    WP_010976834.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02696; AAL02696; RC0158.
    GeneIDi928031.
    KEGGirco:RC0158.
    PATRICi17887451. VBIRicCon45613_0187.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02696.1 .
    PIRi F97719.
    RefSeqi NP_359795.1. NC_003103.1.
    WP_010976834.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92JA9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0158.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02696 ; AAL02696 ; RC0158 .
    GeneIDi 928031.
    KEGGi rco:RC0158.
    PATRICi 17887451. VBIRicCon45613_0187.

    Phylogenomic databases

    eggNOGi COG1159.
    HOGENOMi HOG000245597.
    KOi K03595.
    OMAi HDNAQIV.
    OrthoDBi EOG68DD1Q.

    Family and domain databases

    Gene3Di 3.30.300.20. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00367. GTPase_Era.
    InterProi IPR005662. GTP-bd_Era.
    IPR006073. GTP_binding_domain.
    IPR015946. KH_dom-like_a/b.
    IPR004044. KH_dom_type_2.
    IPR009019. KH_prok-type.
    IPR027417. P-loop_NTPase.
    IPR005728. Rickett_RPE.
    IPR005225. Small_GTP-bd_dom.
    [Graphical view ]
    Pfami PF07650. KH_2. 1 hit.
    PF01926. MMR_HSR1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF54814. SSF54814. 1 hit.
    TIGRFAMsi TIGR00436. era. 1 hit.
    TIGR01045. RPE1. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51713. G_ERA. 1 hit.
    PS50823. KH_TYPE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiERA_RICCN
    AccessioniPrimary (citable) accession number: Q92JA9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 27, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3