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Q92J98 (DHSD_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinate dehydrogenase hydrophobic membrane anchor subunit
Gene names
Name:sdhD
Ordered Locus Names:RC0169
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length126 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Membrane-anchoring subunit of succinate dehydrogenase (SDH) By similarity.

Cofactor

Heme group. The heme is bound between the two transmembrane subunits By similarity.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle.

Subunit structure

Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 126126Succinate dehydrogenase hydrophobic membrane anchor subunit
PRO_0000158677

Regions

Topological domain1 – 2424Cytoplasmic By similarity
Transmembrane25 – 4521Helical; By similarity
Topological domain46 – 6823Periplasmic By similarity
Transmembrane69 – 9022Helical; By similarity
Topological domain91 – 10010Cytoplasmic By similarity
Transmembrane101 – 12424Helical; By similarity

Sites

Metal binding811Iron (heme axial ligand); shared with second transmembrane subunit By similarity
Binding site931Ubiquinone By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92J98 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 72B93A63BF0B2C13

FASTA12614,403
        10         20         30         40         50         60 
MVYDFKAEIV KAKNSGSAKS GSHHWLLQRV TGIILALCSV WLIYFTLTNK NNDINIIMLW 

        70         80         90        100        110        120 
ELKKPFNVVA LLITVVISLY HAMLGMRVVI EDYISYHKLR NTLIIIVQLF CIVTIVAFVV 


ALFYKG 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL02707.1.
PIRA97721.
RefSeqNP_359806.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92J98.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0169.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL02707; AAL02707; RC0169.
GeneID928022.
KEGGrco:RC0169.
PATRIC17887473. VBIRicCon45613_0198.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2142.
HOGENOMHOG000139244.
KOK00242.
OMAIIMWELK.
OrthoDBEOG6X3W76.

Enzyme and pathway databases

UniPathwayUPA00223.

Family and domain databases

InterProIPR014312. Succ_DH_anchor.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view]
PfamPF01127. Sdh_cyt. 1 hit.
[Graphical view]
TIGRFAMsTIGR02968. succ_dehyd_anc. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDHSD_RICCN
AccessionPrimary (citable) accession number: Q92J98
Entry history
Integrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia conorii

(strain Malish 7): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways