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Q92J98

- DHSD_RICCN

UniProt

Q92J98 - DHSD_RICCN

Protein

Succinate dehydrogenase hydrophobic membrane anchor subunit

Gene

sdhD

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Membrane-anchoring subunit of succinate dehydrogenase (SDH).By similarity

    Cofactori

    Heme group. The heme is bound between the two transmembrane subunits By similarity.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi81 – 811Iron (heme axial ligand); shared with second transmembrane subunitBy similarity
    Binding sitei93 – 931UbiquinoneBy similarity

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. metal ion binding Source: UniProtKB-KW
    3. succinate dehydrogenase activity Source: InterPro

    GO - Biological processi

    1. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Biological processi

    Electron transport, Transport, Tricarboxylic acid cycle

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00223.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Succinate dehydrogenase hydrophobic membrane anchor subunit
    Gene namesi
    Name:sdhD
    Ordered Locus Names:RC0169
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 126126Succinate dehydrogenase hydrophobic membrane anchor subunitPRO_0000158677Add
    BLAST

    Interactioni

    Subunit structurei

    Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.By similarity

    Protein-protein interaction databases

    STRINGi272944.RC0169.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92J98.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2424CytoplasmicBy similarityAdd
    BLAST
    Topological domaini46 – 6823PeriplasmicBy similarityAdd
    BLAST
    Topological domaini91 – 10010CytoplasmicBy similarity

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei25 – 4521HelicalBy similarityAdd
    BLAST
    Transmembranei69 – 9022HelicalBy similarityAdd
    BLAST
    Transmembranei101 – 12424HelicalBy similarityAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG2142.
    HOGENOMiHOG000139244.
    KOiK00242.
    OMAiIIMWELK.
    OrthoDBiEOG6X3W76.

    Family and domain databases

    InterProiIPR014312. Succ_DH_anchor.
    IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
    [Graphical view]
    PfamiPF01127. Sdh_cyt. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02968. succ_dehyd_anc. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q92J98-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVYDFKAEIV KAKNSGSAKS GSHHWLLQRV TGIILALCSV WLIYFTLTNK    50
    NNDINIIMLW ELKKPFNVVA LLITVVISLY HAMLGMRVVI EDYISYHKLR 100
    NTLIIIVQLF CIVTIVAFVV ALFYKG 126
    Length:126
    Mass (Da):14,403
    Last modified:December 1, 2001 - v1
    Checksum:i72B93A63BF0B2C13
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02707.1.
    PIRiA97721.
    RefSeqiNP_359806.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02707; AAL02707; RC0169.
    GeneIDi928022.
    KEGGirco:RC0169.
    PATRICi17887473. VBIRicCon45613_0198.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02707.1 .
    PIRi A97721.
    RefSeqi NP_359806.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92J98.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0169.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02707 ; AAL02707 ; RC0169 .
    GeneIDi 928022.
    KEGGi rco:RC0169.
    PATRICi 17887473. VBIRicCon45613_0198.

    Phylogenomic databases

    eggNOGi COG2142.
    HOGENOMi HOG000139244.
    KOi K00242.
    OMAi IIMWELK.
    OrthoDBi EOG6X3W76.

    Enzyme and pathway databases

    UniPathwayi UPA00223 .

    Family and domain databases

    InterProi IPR014312. Succ_DH_anchor.
    IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
    [Graphical view ]
    Pfami PF01127. Sdh_cyt. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02968. succ_dehyd_anc. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiDHSD_RICCN
    AccessioniPrimary (citable) accession number: Q92J98
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 11, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Rickettsia conorii
      (strain Malish 7): entries and gene names

    External Data

    Dasty 3