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Q92J98

- DHSD_RICCN

UniProt

Q92J98 - DHSD_RICCN

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Protein

Succinate dehydrogenase hydrophobic membrane anchor subunit

Gene

sdhD

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Membrane-anchoring subunit of succinate dehydrogenase (SDH).By similarity

Cofactori

Heme group. The heme is bound between the two transmembrane subunits By similarity.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi81 – 811Iron (heme axial ligand); shared with second transmembrane subunitBy similarity
Binding sitei93 – 931UbiquinoneBy similarity

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
  3. succinate dehydrogenase activity Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport, Tricarboxylic acid cycle

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00223.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase hydrophobic membrane anchor subunit
Gene namesi
Name:sdhD
Ordered Locus Names:RC0169
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 126126Succinate dehydrogenase hydrophobic membrane anchor subunitPRO_0000158677Add
BLAST

Interactioni

Subunit structurei

Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.By similarity

Protein-protein interaction databases

STRINGi272944.RC0169.

Structurei

3D structure databases

ProteinModelPortaliQ92J98.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2424CytoplasmicBy similarityAdd
BLAST
Topological domaini46 – 6823PeriplasmicBy similarityAdd
BLAST
Topological domaini91 – 10010CytoplasmicBy similarity

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei25 – 4521HelicalBy similarityAdd
BLAST
Transmembranei69 – 9022HelicalBy similarityAdd
BLAST
Transmembranei101 – 12424HelicalBy similarityAdd
BLAST

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2142.
HOGENOMiHOG000139244.
KOiK00242.
OMAiIIMWELK.
OrthoDBiEOG6X3W76.

Family and domain databases

InterProiIPR014312. Succ_DH_anchor.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view]
PfamiPF01127. Sdh_cyt. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02968. succ_dehyd_anc. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92J98-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVYDFKAEIV KAKNSGSAKS GSHHWLLQRV TGIILALCSV WLIYFTLTNK
60 70 80 90 100
NNDINIIMLW ELKKPFNVVA LLITVVISLY HAMLGMRVVI EDYISYHKLR
110 120
NTLIIIVQLF CIVTIVAFVV ALFYKG
Length:126
Mass (Da):14,403
Last modified:December 1, 2001 - v1
Checksum:i72B93A63BF0B2C13
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL02707.1.
PIRiA97721.
RefSeqiNP_359806.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02707; AAL02707; RC0169.
GeneIDi928022.
KEGGirco:RC0169.
PATRICi17887473. VBIRicCon45613_0198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL02707.1 .
PIRi A97721.
RefSeqi NP_359806.1. NC_003103.1.

3D structure databases

ProteinModelPortali Q92J98.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0169.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL02707 ; AAL02707 ; RC0169 .
GeneIDi 928022.
KEGGi rco:RC0169.
PATRICi 17887473. VBIRicCon45613_0198.

Phylogenomic databases

eggNOGi COG2142.
HOGENOMi HOG000139244.
KOi K00242.
OMAi IIMWELK.
OrthoDBi EOG6X3W76.

Enzyme and pathway databases

UniPathwayi UPA00223 .

Family and domain databases

InterProi IPR014312. Succ_DH_anchor.
IPR000701. Succ_DH_Fumarate_Rdtase_TM-su.
[Graphical view ]
Pfami PF01127. Sdh_cyt. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02968. succ_dehyd_anc. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiDHSD_RICCN
AccessioniPrimary (citable) accession number: Q92J98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia conorii
    (strain Malish 7): entries and gene names

External Data

Dasty 3