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Q92J93

- EFG_RICCN

UniProt

Q92J93 - EFG_RICCN

Protein

Elongation factor G

Gene

fusA

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi17 – 248GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi135 – 1384GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor GUniRule annotation
    Short name:
    EF-GUniRule annotation
    Gene namesi
    Name:fusAUniRule annotation
    Ordered Locus Names:RC0174
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 699699Elongation factor GPRO_0000091196Add
    BLAST

    Proteomic databases

    PRIDEiQ92J93.

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC0174.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92J93.
    SMRiQ92J93. Positions 5-694.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini8 – 283276tr-type GAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0480.
    HOGENOMiHOG000231585.
    KOiK02355.
    OMAiLMKAYYF.
    OrthoDBiEOG6X6RBF.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    3.30.70.240. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00054_B. EF_G_EF_2_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR009022. EFG_III-V.
    IPR000640. EFG_V.
    IPR027417. P-loop_NTPase.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR004540. Transl_elong_EFG/EF2.
    IPR005517. Transl_elong_EFG/EF2_IV.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PfamiPF00679. EFG_C. 1 hit.
    PF14492. EFG_II. 1 hit.
    PF03764. EFG_IV. 1 hit.
    PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SMARTiSM00838. EFG_C. 1 hit.
    SM00889. EFG_IV. 1 hit.
    [Graphical view]
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF54211. SSF54211. 1 hit.
    SSF54980. SSF54980. 2 hits.
    TIGRFAMsiTIGR00484. EF-G. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92J93-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKINKLEHI RNIGICAHID AGKTTTTERI LYYTGKSHKI GEVHEGGATM    50
    DWMEQEQERG ITITSAATTC RWQDKIINII DTPGHVDFTI EVERSLRVLD 100
    GAVAVFDGVA GVEPQSETVW RQADKYNVPR MCFVNKMDRM GADFYRCVEM 150
    LKDRLGAKPL VIQLPVGIEE NFKGIIDLIK MKAVIWKDEA LGAEYFEEDI 200
    PADMKDKAEE YRAKLLDMVV ELDDHVMEKY LSGEEVTAEE IKRLIRKGTI 250
    SAAFYPVLCG SAFKNKGVQP LLDAVVDFLP SPIDIGIVKG MEVSTGEEKD 300
    FPISVTEPFA ALAFKIMNDP FVGSLTFIRI YSGKITSGTT VINTVKNKRE 350
    KIGRMLLMHA NNREDVKEAS AGDIVALAGL KDTTTGDTLS DIDQQVILER 400
    MEFPEPVIEL AVEPKSTADQ EKMGLALSRL AAEDPSFRVS TDYETGQTVI 450
    KGMGELHLEI IIDRMRREFK VEANIGAPQV AYRETITKVC EIDYTHKKQS 500
    GGAGQFARVK IIFEPLKEVK DLKDEDKNKI FVFESKIIGG AVPKEYIPGV 550
    EKGLNNIRET GVIAGYPMID FKATLVDGAF HDVDSSVLAF EIAAKAAFRE 600
    GMPKGNPKLL EPIMQVEVIT PDEYMGDIIG DLNSRRGQIQ SMDPRGNAQV 650
    VTANVPLAEM FGYVNTLRSL SQGRAQFSMI FSHYDQVPSQ VADIIKAKK 699
    Length:699
    Mass (Da):77,708
    Last modified:December 1, 2001 - v1
    Checksum:iC51222EB05D0CE54
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02712.1.
    PIRiF97721.
    RefSeqiNP_359811.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02712; AAL02712; RC0174.
    GeneIDi928019.
    KEGGirco:RC0174.
    PATRICi17887483. VBIRicCon45613_0203.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02712.1 .
    PIRi F97721.
    RefSeqi NP_359811.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92J93.
    SMRi Q92J93. Positions 5-694.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0174.

    Proteomic databases

    PRIDEi Q92J93.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02712 ; AAL02712 ; RC0174 .
    GeneIDi 928019.
    KEGGi rco:RC0174.
    PATRICi 17887483. VBIRicCon45613_0203.

    Phylogenomic databases

    eggNOGi COG0480.
    HOGENOMi HOG000231585.
    KOi K02355.
    OMAi LMKAYYF.
    OrthoDBi EOG6X6RBF.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    3.30.70.240. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00054_B. EF_G_EF_2_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR009022. EFG_III-V.
    IPR000640. EFG_V.
    IPR027417. P-loop_NTPase.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR004540. Transl_elong_EFG/EF2.
    IPR005517. Transl_elong_EFG/EF2_IV.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    Pfami PF00679. EFG_C. 1 hit.
    PF14492. EFG_II. 1 hit.
    PF03764. EFG_IV. 1 hit.
    PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SMARTi SM00838. EFG_C. 1 hit.
    SM00889. EFG_IV. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF54211. SSF54211. 1 hit.
    SSF54980. SSF54980. 2 hits.
    TIGRFAMsi TIGR00484. EF-G. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiEFG_RICCN
    AccessioniPrimary (citable) accession number: Q92J93
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 31, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3