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Protein

Probable cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene namesi
Name:ctaE
Synonyms:coxC
Ordered Locus Names:RC0240
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4621HelicalSequence AnalysisAdd
BLAST
Transmembranei51 – 7121HelicalSequence AnalysisAdd
BLAST
Transmembranei94 – 11421HelicalSequence AnalysisAdd
BLAST
Transmembranei179 – 19921HelicalSequence AnalysisAdd
BLAST
Transmembranei217 – 23721HelicalSequence AnalysisAdd
BLAST
Transmembranei261 – 28121HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 283283Probable cytochrome c oxidase subunit 3PRO_0000280889Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0240.

Structurei

3D structure databases

ProteinModelPortaliQ92J29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1845.
HOGENOMiHOG000264954.
KOiK02276.
OMAiGFFWAFY.
OrthoDBiEOG6V7BK2.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92J29-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSQKIILNNS YSITKSHLFH IVDPSPWPVL TSFALLLLVI GGVSFMHGYK
60 70 80 90 100
FNIYILSAGI ISVGYCLYSW WRDIVKEGIV EHQHTSPVRK GLQIGMALFI
110 120 130 140 150
LTEIVFFGVF FASFFKSSLS PVGLLDGVWV VKQGIWPPPT IKTFEPFDIP
160 170 180 190 200
FINTLILLLS GTTVTWAHYA LEEKNQKDCV TALALTILLG IFFTTMQAYE
210 220 230 240 250
YYHAAFKFTD GIYASNFYLA TGFHGAHVII GTIFLIICYF RAKRGDFTTE
260 270 280
GNGHLGFECA AWYWHFVDVV WLFLFTFVYI FGS
Length:283
Mass (Da):32,119
Last modified:March 20, 2007 - v2
Checksum:i961425CD14EB5C65
GO

Sequence cautioni

The sequence AAL02778.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02778.1. Different initiation.
PIRiH97729.
RefSeqiNP_359877.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02778; AAL02778; RC0240.
GeneIDi927935.
KEGGirco:RC0240.
PATRICi17887639. VBIRicCon45613_0279.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02778.1. Different initiation.
PIRiH97729.
RefSeqiNP_359877.1. NC_003103.1.

3D structure databases

ProteinModelPortaliQ92J29.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272944.RC0240.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL02778; AAL02778; RC0240.
GeneIDi927935.
KEGGirco:RC0240.
PATRICi17887639. VBIRicCon45613_0279.

Phylogenomic databases

eggNOGiCOG1845.
HOGENOMiHOG000264954.
KOiK02276.
OMAiGFFWAFY.
OrthoDBiEOG6V7BK2.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiCOX3_RICCN
AccessioniPrimary (citable) accession number: Q92J29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: January 7, 2015
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.