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Q92J29 (COX3_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Synonyms:coxC
Ordered Locus Names:RC0240
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length283 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence caution

The sequence AAL02778.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 283283Probable cytochrome c oxidase subunit 3
PRO_0000280889

Regions

Transmembrane26 – 4621Helical; Potential
Transmembrane51 – 7121Helical; Potential
Transmembrane94 – 11421Helical; Potential
Transmembrane179 – 19921Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane261 – 28121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q92J29 [UniParc].

Last modified March 20, 2007. Version 2.
Checksum: 961425CD14EB5C65

FASTA28332,119
        10         20         30         40         50         60 
MSQKIILNNS YSITKSHLFH IVDPSPWPVL TSFALLLLVI GGVSFMHGYK FNIYILSAGI 

        70         80         90        100        110        120 
ISVGYCLYSW WRDIVKEGIV EHQHTSPVRK GLQIGMALFI LTEIVFFGVF FASFFKSSLS 

       130        140        150        160        170        180 
PVGLLDGVWV VKQGIWPPPT IKTFEPFDIP FINTLILLLS GTTVTWAHYA LEEKNQKDCV 

       190        200        210        220        230        240 
TALALTILLG IFFTTMQAYE YYHAAFKFTD GIYASNFYLA TGFHGAHVII GTIFLIICYF 

       250        260        270        280 
RAKRGDFTTE GNGHLGFECA AWYWHFVDVV WLFLFTFVYI FGS 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL02778.1. Different initiation.
PIRH97729.
RefSeqNP_359877.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92J29.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0240.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL02778; AAL02778; RC0240.
GeneID927935.
KEGGrco:RC0240.
PATRIC17887639. VBIRicCon45613_0279.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000264954.
KOK02276.
OMAFFWAFYH.
OrthoDBEOG6V7BK2.
ProtClustDBCLSK870788.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_RICCN
AccessionPrimary (citable) accession number: Q92J29
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 20, 2007
Last modified: April 16, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names