Q92J06 (HSCB_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Co-chaperone protein HscB homolog

Gene names

Name:	hscB
Ordered Locus Names:	RC0263

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA By similarity. HAMAP-Rule MF_00682
Subunit structure	Interacts with HscA and stimulates its ATPase activity By similarity.
Sequence similarities	Belongs to the HscB family. Contains 1 J domain.

Ontologies

Keywords
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: HAMAP protein oligomerization Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 166	166	Co-chaperone protein HscB homolog HAMAP-Rule MF_00682		PRO_0000070983
Regions
	Domain	3 – 73	71	J

Sequences

	Sequence		Length	Mass (Da)
	Q92J06 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: B275C4B5484EAF18	FASTA	166	19,568
	10 20 30 40 50 60 MQNYFQLLGL PQEYNINLKI LEKQYFAMQV KYHPDKAKTL QEKEQNLITA AELNNAYSTL 70 80 90 100 110 120 KDALKRAEYM LLLQNINLND EKTRSLLSPL ELSIFWDEME IIENTILFSD LEKIKDKYEL 130 140 150 160 MKKLEIDSLK QAFEEQNLSD ATIKTSKLKY IGTLLHKLQE KIKSCK

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL02801.1.
PIR	G97732.
RefSeq	NP_359900.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92J06.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC0263.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL02801; AAL02801; RC0263.
GeneID	927915.
KEGG	rco:RC0263.
PATRIC	17887683. VBIRicCon45613_0301.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1076.
HOGENOM	HOG000063516.
KO	K04082.
OMA	SKLKYIR.
ProtClustDB	PRK01356.
Family and domain databases
Gene3D	1.10.287.110. 1 hit.
HAMAP	MF_00682. HscB.
InterPro	IPR001623. DnaJ_domain. IPR004640. HscB. IPR009073. HscB_oligo_C. [Graphical view]
PANTHER	PTHR14021. PTHR14021. 1 hit.
Pfam	PF00226. DnaJ. 1 hit. [Graphical view]
SMART	SM00271. DnaJ. 1 hit. [Graphical view]
SUPFAM	SSF46565. DnaJ_N. 1 hit. SSF47144. HSC20_C. 1 hit.
TIGRFAMs	TIGR00714. hscB. 1 hit.
PROSITE	PS00636. DNAJ_1. False negative. PS50076. DNAJ_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HSCB_RICCN

Accession

Primary (citable) accession number: Q92J06

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2003
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program