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Q92J02 (GLRX1_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaredoxin-1
Gene names
Name:grxC1
Synonyms:grx
Ordered Locus Names:RC0267
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length102 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins By similarity.

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glutaredoxin family.

Contains 1 glutaredoxin domain.

Ontologies

Keywords
   Biological processElectron transport
Transport
   Cellular componentCytoplasm
   DomainRedox-active center
   PTMDisulfide bond
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcell redox homeostasis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionelectron carrier activity

Inferred from electronic annotation. Source: InterPro

protein disulfide oxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 102102Glutaredoxin-1
PRO_0000288735

Regions

Domain1 – 9696Glutaredoxin

Amino acid modifications

Disulfide bond17 ↔ 20Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92J02 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 7B7844F027B2C989

FASTA10211,331
        10         20         30         40         50         60 
MNKAILHTII VYTLASCPYC IKAKALLDEK NVAYEEIEVS NFTQEEKEKF IKKSGGKKTV 

        70         80         90        100 
PQIFIDNMHV GGCDALFDLE KEGRLDKLLE NQPKTTSPAA GA 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL02805.1.
PIRC97733.
RefSeqNP_359904.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92J02.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0267.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL02805; AAL02805; RC0267.
GeneID927911.
KEGGrco:RC0267.
PATRIC17887689. VBIRicCon45613_0304.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0695.
HOGENOMHOG000095203.
KOK03676.
OMAMTRKAGR.
OrthoDBEOG6Z3KS6.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR011767. GLR_AS.
IPR002109. Glutaredoxin.
IPR014025. Glutaredoxin_subgr.
IPR011900. GRX_bact.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PRINTSPR00160. GLUTAREDOXIN.
SUPFAMSSF52833. SSF52833. 1 hit.
TIGRFAMsTIGR02181. GRX_bact. 1 hit.
PROSITEPS00195. GLUTAREDOXIN_1. 1 hit.
PS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLRX1_RICCN
AccessionPrimary (citable) accession number: Q92J02
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names