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Protein

Cytochrome b

Gene

petB

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.By similarity

Cofactori

hemeBy similarityNote: Binds 2 heme groups non-covalently.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi95Iron 1 (heme b562 axial ligand)1
Metal bindingi109Iron 2 (heme b566 axial ligand)1
Metal bindingi196Iron 1 (heme b562 axial ligand)1
Metal bindingi210Iron 2 (heme b566 axial ligand)1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome b
Gene namesi
Name:petB
Synonyms:cytB
Ordered Locus Names:RC0359
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000000816 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei245 – 265HelicalSequence analysisAdd BLAST21
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21
Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Transmembranei339 – 359HelicalSequence analysisAdd BLAST21
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002809341 – 398Cytochrome bAdd BLAST398

Interactioni

Subunit structurei

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ92IR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome b family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000255206.
KOiK00412.
OMAiFMDWVDA.
OrthoDBiPOG091H05GV.

Family and domain databases

CDDicd00284. Cytochrome_b_N. 1 hit.
Gene3Di1.20.810.10. 1 hit.
InterProiIPR005798. Cyt_b/b6_C.
IPR005797. Cyt_b/b6_N.
IPR027387. Cytb/b6-like.
IPR030689. Cytochrome_b.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PfamiPF00032. Cytochrom_B_C. 1 hit.
PF00033. Cytochrome_B. 1 hit.
[Graphical view]
PIRSFiPIRSF038885. COB. 1 hit.
SUPFAMiSSF81342. SSF81342. 1 hit.
SSF81648. SSF81648. 1 hit.
PROSITEiPS51003. CYTB_CTER. 1 hit.
PS51002. CYTB_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92IR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEDITPKKP NAIIEWIDYR LPIFAFLKHF SHYQTPKNLN YLWNLGSIAG
60 70 80 90 100
IALVIQIITG VILAMHYTPH VDHAFDSVER IMRNVNYGWL LRYTHAVGAS
110 120 130 140 150
MFFAAVYLHI ARGLYYGSYK APRELLWHIG IIIFLTMMAT AFMGYVLPWG
160 170 180 190 200
QMSYWGATVI TNLFSAIPLI GEFIVTWLWG GFSVDNPTLN RFFSLHYLLP
210 220 230 240 250
FIIVALVMLH LVALHQHGSN NPKGIDVKSP KDTIPFHPYY TVKDFVGFGV
260 270 280 290 300
YFIIFAYFIF YEPNYLGHPD NYIPANPLVT PAHIVPEWYF LPFYAILRAM
310 320 330 340 350
PSKLGGVLLM FGSIFVLFLL PWLDTSKVRS SNYRPIYRMA FWIFMADCLL
360 370 380 390
LGYLGGQPAE EPYITISRFA ACYYFFHVLV ALPLIGKYEK PLPLPEEL
Length:398
Mass (Da):45,829
Last modified:December 1, 2001 - v1
Checksum:i148A8A349574B7BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02897.1.
PIRiG97744.
RefSeqiWP_010977014.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL02897; AAL02897; RC0359.
GeneIDi928546.
KEGGirco:RC0359.
PATRICi17887904. VBIRicCon45613_0408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL02897.1.
PIRiG97744.
RefSeqiWP_010977014.1. NC_003103.1.

3D structure databases

ProteinModelPortaliQ92IR1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL02897; AAL02897; RC0359.
GeneIDi928546.
KEGGirco:RC0359.
PATRICi17887904. VBIRicCon45613_0408.

Phylogenomic databases

HOGENOMiHOG000255206.
KOiK00412.
OMAiFMDWVDA.
OrthoDBiPOG091H05GV.

Family and domain databases

CDDicd00284. Cytochrome_b_N. 1 hit.
Gene3Di1.20.810.10. 1 hit.
InterProiIPR005798. Cyt_b/b6_C.
IPR005797. Cyt_b/b6_N.
IPR027387. Cytb/b6-like.
IPR030689. Cytochrome_b.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PfamiPF00032. Cytochrom_B_C. 1 hit.
PF00033. Cytochrome_B. 1 hit.
[Graphical view]
PIRSFiPIRSF038885. COB. 1 hit.
SUPFAMiSSF81342. SSF81342. 1 hit.
SSF81648. SSF81648. 1 hit.
PROSITEiPS51003. CYTB_CTER. 1 hit.
PS51002. CYTB_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCYB_RICCN
AccessioniPrimary (citable) accession number: Q92IR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.By similarity

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.