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Q92IR1 (CYB_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome b
Gene names
Name:petB
Synonyms:cytB
Ordered Locus Names:RC0359
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis By similarity.

Cofactor

Binds 2 heme groups non-covalently By similarity.

Subunit structure

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm By similarity.

Sequence similarities

Belongs to the cytochrome b family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Cytochrome b
PRO_0000280934

Regions

Transmembrane45 – 6521Helical; Potential
Transmembrane96 – 11621Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane164 – 18421Helical; Potential
Transmembrane192 – 21221Helical; Potential
Transmembrane245 – 26521Helical; Potential
Transmembrane277 – 29721Helical; Potential
Transmembrane304 – 32421Helical; Potential
Transmembrane339 – 35921Helical; Potential
Transmembrane366 – 38621Helical; Potential

Sites

Metal binding951Iron 1 (heme b562 axial ligand)
Metal binding1091Iron 2 (heme b566 axial ligand)
Metal binding1961Iron 1 (heme b562 axial ligand)
Metal binding2101Iron 2 (heme b566 axial ligand)

Sequences

Sequence LengthMass (Da)Tools
Q92IR1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 148A8A349574B7BF

FASTA39845,829
        10         20         30         40         50         60 
MNEDITPKKP NAIIEWIDYR LPIFAFLKHF SHYQTPKNLN YLWNLGSIAG IALVIQIITG 

        70         80         90        100        110        120 
VILAMHYTPH VDHAFDSVER IMRNVNYGWL LRYTHAVGAS MFFAAVYLHI ARGLYYGSYK 

       130        140        150        160        170        180 
APRELLWHIG IIIFLTMMAT AFMGYVLPWG QMSYWGATVI TNLFSAIPLI GEFIVTWLWG 

       190        200        210        220        230        240 
GFSVDNPTLN RFFSLHYLLP FIIVALVMLH LVALHQHGSN NPKGIDVKSP KDTIPFHPYY 

       250        260        270        280        290        300 
TVKDFVGFGV YFIIFAYFIF YEPNYLGHPD NYIPANPLVT PAHIVPEWYF LPFYAILRAM 

       310        320        330        340        350        360 
PSKLGGVLLM FGSIFVLFLL PWLDTSKVRS SNYRPIYRMA FWIFMADCLL LGYLGGQPAE 

       370        380        390 
EPYITISRFA ACYYFFHVLV ALPLIGKYEK PLPLPEEL 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL02897.1.
PIRG97744.
RefSeqNP_359996.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92IR1.
SMRQ92IR1. Positions 8-398.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0359.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL02897; AAL02897; RC0359.
GeneID928546.
KEGGrco:RC0359.
PATRIC17887904. VBIRicCon45613_0408.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1290.
HOGENOMHOG000255206.
KOK00412.
OMAEWYFLAN.
OrthoDBEOG6P3338.
ProtClustDBCLSK870835.

Family and domain databases

Gene3D1.20.810.10. 1 hit.
InterProIPR016175. Cyt_b/b6.
IPR005798. Cyt_b/b6_C.
IPR005797. Cyt_b/b6_N.
IPR027387. Cytb/b6-like.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PANTHERPTHR19271:SF0. PTHR19271:SF0. 1 hit.
PfamPF00032. Cytochrom_B_C. 1 hit.
PF13631. Cytochrom_B_N_2. 1 hit.
[Graphical view]
SUPFAMSSF81342. SSF81342. 1 hit.
SSF81648. SSF81648. 1 hit.
PROSITEPS51003. CYTB_CTER. 1 hit.
PS51002. CYTB_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCYB_RICCN
AccessionPrimary (citable) accession number: Q92IR1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names