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Q92IQ2

- RF2_RICCN

UniProt

Q92IQ2 - RF2_RICCN

Protein

Peptide chain release factor 2

Gene

prfB

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.UniRule annotation

    GO - Molecular functioni

    1. translation release factor activity, codon specific Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein biosynthesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptide chain release factor 2UniRule annotation
    Short name:
    RF-2UniRule annotation
    Gene namesi
    Name:prfBUniRule annotation
    Ordered Locus Names:RC0368
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 368368Peptide chain release factor 2PRO_0000166838Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei250 – 2501N5-methylglutamineUniRule annotation

    Post-translational modificationi

    Methylated by PrmC. Methylation increases the termination efficiency of RF2.UniRule annotation

    Keywords - PTMi

    Methylation

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC0368.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92IQ2.
    SMRiQ92IQ2. Positions 4-364.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1186.
    HOGENOMiHOG000074814.
    KOiK02836.
    OMAiDPNVWNN.
    OrthoDBiEOG6TN48J.

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    HAMAPiMF_00094. Rel_fac_2.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR020853. Peptide_chain_release_fac2_bac.
    IPR004374. PrfB.
    [Graphical view]
    PANTHERiPTHR11075:SF6. PTHR11075:SF6. 1 hit.
    PfamiPF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view]
    SMARTiSM00937. PCRF. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00020. prfB. 1 hit.
    PROSITEiPS00745. RF_PROK_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92IQ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRAEIENYVK KIEQSLELLW RSLDVEASTE RLNALEELTA DPSLWNDQAN    50
    AQKLLREKSN LEEKLNAFNK LKSNLKDALE LEEMAEAEND LETLSQIEQD 100
    LKNLSIIAAK FETECLFSGE ADGNNCFLEI NAGAGGTESH DWASIMMRMY 150
    LRFAERLGFK TEIINMINGE EAGIKSCTIR IIGKRAYGWF KTETGVHRLV 200
    RISPFNAAGK RMTSFASSWV YPEIDDNIAI TIEDKDLRID TFRASGAGGQ 250
    HVNTTDSAVR ITHIPTGTVT QCQSDRSQHK NKAQAMKMLQ AKLYELEMQK 300
    RTDSVNEQNA AKTDNSWGHQ IRSYVLQPYH MVKDLRTDYE TSDTKGVLDG 350
    DLEEFVSAHL AMNVGGKK 368
    Length:368
    Mass (Da):41,540
    Last modified:December 1, 2001 - v1
    Checksum:iA63C0FD338F7081F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02906.1.
    PIRiH97745.
    RefSeqiNP_360005.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL02906; AAL02906; RC0368.
    GeneIDi928554.
    KEGGirco:RC0368.
    PATRICi17887924. VBIRicCon45613_0418.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL02906.1 .
    PIRi H97745.
    RefSeqi NP_360005.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92IQ2.
    SMRi Q92IQ2. Positions 4-364.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0368.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL02906 ; AAL02906 ; RC0368 .
    GeneIDi 928554.
    KEGGi rco:RC0368.
    PATRICi 17887924. VBIRicCon45613_0418.

    Phylogenomic databases

    eggNOGi COG1186.
    HOGENOMi HOG000074814.
    KOi K02836.
    OMAi DPNVWNN.
    OrthoDBi EOG6TN48J.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    HAMAPi MF_00094. Rel_fac_2.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR020853. Peptide_chain_release_fac2_bac.
    IPR004374. PrfB.
    [Graphical view ]
    PANTHERi PTHR11075:SF6. PTHR11075:SF6. 1 hit.
    Pfami PF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view ]
    SMARTi SM00937. PCRF. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00020. prfB. 1 hit.
    PROSITEi PS00745. RF_PROK_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiRF2_RICCN
    AccessioniPrimary (citable) accession number: Q92IQ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3