Q92ID7 (NUOC_RICCN) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 66.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: NADH-quinone oxidoreductase subunit C EC=1.6.99.5 Alternative name(s): NADH dehydrogenase I subunit C NDH-1 subunit C | ||||
| Gene names |
| ||||
| Organism | Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 272944 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group |
Protein attributes
| Sequence length | 242 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity. HAMAP MF_01357 |
| Catalytic activity | NADH + quinone = NAD+ + quinol. HAMAP MF_01357 |
| Subunit structure | NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex By similarity. |
| Subcellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP MF_01357. |
| Sequence similarities | Belongs to the complex I 30 kDa subunit family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transport |
| Cellular component | Cell inner membrane Cell membrane Membrane |
| Ligand | NAD Ubiquinone |
| Molecular function | Oxidoreductase |
| PTM | Quinone |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | transport Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: InterPro quinone bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 242 | 242 | NADH-quinone oxidoreductase subunit C HAMAP MF_01357 | PRO_0000287858 | |||||
Regions | |||||||||
| Region | 67 – 101 | 35 | Insert HAMAP MF_01357 | ||||||
Sequences
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References
| [1] | "Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE006914 Genomic DNA. Translation: AAL03021.1. |
| PIR | C97760. |
| RefSeq | NP_360120.1. NC_003103.1. |
3D structure databases | |
| ProteinModelPortal | Q92ID7. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 928702. |
| GenomeReviews | Gene locus RC0483 in contig AE006914_GR. |
| KEGG | rco:RC0483. |
| NMPDR | fig|272944.1.peg.483. |
| PATRIC | 17888200. VBIRicCon45613_0554. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| OMA | LTGYTQV. |
| ProtClustDB | PRK06074. |
Enzyme and pathway databases | |
| BioCyc | RCON272944:RC0483-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01357. NDH1_NuoC. [Tree] |
| InterPro | IPR010218. NADH_DH_suC. IPR001268. NADH_UbQ_OxRdtase_30kDa_su. IPR022436. RPE2. [Graphical view] |
| KO | K00332. |
| Pfam | PF00329. Complex1_30kDa. 1 hit. [Graphical view] |
| ProDom | PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR03774. RPE2. 1 hit. |
| PROSITE | PS00542. COMPLEX1_30K. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NUOC_RICCN | ||||||||
| Accession | Primary (citable) accession number: Q92ID7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Rickettsia conorii (strain Malish 7): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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