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Q92IC9 (XERD_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tyrosine recombinase XerD
Gene names
Name:xerD
Ordered Locus Names:RC0491
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids By similarity. HAMAP-Rule MF_01807

Subunit structure

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01807.

Sequence similarities

Belongs to the 'phage' integrase family. XerD subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Tyrosine recombinase XerD HAMAP-Rule MF_01807
PRO_0000095410

Sites

Active site1451 By similarity
Active site1761 By similarity
Active site2511 By similarity
Active site2541 By similarity
Active site2771 By similarity
Active site2861O-(3'-phospho-DNA)-tyrosine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92IC9 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 734AA7CCECA351AC

FASTA30634,699
        10         20         30         40         50         60 
MGFIAQFLEM LLAERALSKN SILSYKRDLF DFQNYLAKHK LSELNITTEN IRDWIEYLAS 

        70         80         90        100        110        120 
NDLQARSINR KISTIKSYYE FLISENHTAF NPVLNVDLPK YQNKLPEILS IAQIKSLLEH 

       130        140        150        160        170        180 
CSQDNSPEGI RLNAMIHLLY ASGLRVSELV SLKLADILTN KTSKGEVRKI FSVLGKGNKE 

       190        200        210        220        230        240 
RVIVINEQAV ISIAKYLTIR GVFVNKAKPR NLIYLFPSSA LAGYMTRQNF AILLKSAALY 

       250        260        270        280        290        300 
AGLNPEYISP HILRHSFASH LLEGGADLRV IQELLGHADI STTQIYTHLQ TNHLKKALLR 


HPLNKN 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03029.1.
PIRC97761.
RefSeqNP_360128.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92IC9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0491.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL03029; AAL03029; RC0491.
GeneID927615.
KEGGrco:RC0491.
PATRIC17888218. VBIRicCon45613_0562.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4974.
HOGENOMHOG000045296.
KOK04763.
OMAPMGELAI.
OrthoDBEOG6PZXFP.

Family and domain databases

Gene3D1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPMF_01807. Recomb_XerD.
MF_01808. Recomb_XerC.
InterProIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMSSF56349. SSF56349. 1 hit.
ProtoNetSearch...

Entry information

Entry nameXERD_RICCN
AccessionPrimary (citable) accession number: Q92IC9
Entry history
Integrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names