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Q92IC9

- XERD_RICCN

UniProt

Q92IC9 - XERD_RICCN

Protein

Tyrosine recombinase XerD

Gene

xerD

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei145 – 1451UniRule annotation
    Active sitei176 – 1761UniRule annotation
    Active sitei251 – 2511UniRule annotation
    Active sitei254 – 2541UniRule annotation
    Active sitei277 – 2771UniRule annotation
    Active sitei286 – 2861O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. chromosome segregation Source: UniProtKB-HAMAP
    4. transposition, DNA-mediated Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Cell cycle, Cell division, Chromosome partition, DNA integration, DNA recombination

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tyrosine recombinase XerDUniRule annotation
    Gene namesi
    Name:xerDUniRule annotation
    Ordered Locus Names:RC0491
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306Tyrosine recombinase XerDPRO_0000095410Add
    BLAST

    Interactioni

    Subunit structurei

    Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotation

    Protein-protein interaction databases

    STRINGi272944.RC0491.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92IC9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 'phage' integrase family. XerD subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4974.
    HOGENOMiHOG000045296.
    KOiK04763.
    OMAiPMGELAI.
    OrthoDBiEOG6PZXFP.

    Family and domain databases

    Gene3Di1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPiMF_01807. Recomb_XerD.
    MF_01808. Recomb_XerC.
    InterProiIPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR011932. Recomb_XerD.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view]
    PfamiPF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56349. SSF56349. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q92IC9-1 [UniParc]FASTAAdd to Basket

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    MGFIAQFLEM LLAERALSKN SILSYKRDLF DFQNYLAKHK LSELNITTEN    50
    IRDWIEYLAS NDLQARSINR KISTIKSYYE FLISENHTAF NPVLNVDLPK 100
    YQNKLPEILS IAQIKSLLEH CSQDNSPEGI RLNAMIHLLY ASGLRVSELV 150
    SLKLADILTN KTSKGEVRKI FSVLGKGNKE RVIVINEQAV ISIAKYLTIR 200
    GVFVNKAKPR NLIYLFPSSA LAGYMTRQNF AILLKSAALY AGLNPEYISP 250
    HILRHSFASH LLEGGADLRV IQELLGHADI STTQIYTHLQ TNHLKKALLR 300
    HPLNKN 306
    Length:306
    Mass (Da):34,699
    Last modified:December 1, 2001 - v1
    Checksum:i734AA7CCECA351AC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03029.1.
    PIRiC97761.
    RefSeqiNP_360128.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL03029; AAL03029; RC0491.
    GeneIDi927615.
    KEGGirco:RC0491.
    PATRICi17888218. VBIRicCon45613_0562.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03029.1 .
    PIRi C97761.
    RefSeqi NP_360128.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92IC9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0491.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL03029 ; AAL03029 ; RC0491 .
    GeneIDi 927615.
    KEGGi rco:RC0491.
    PATRICi 17888218. VBIRicCon45613_0562.

    Phylogenomic databases

    eggNOGi COG4974.
    HOGENOMi HOG000045296.
    KOi K04763.
    OMAi PMGELAI.
    OrthoDBi EOG6PZXFP.

    Family and domain databases

    Gene3Di 1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPi MF_01807. Recomb_XerD.
    MF_01808. Recomb_XerC.
    InterProi IPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR011932. Recomb_XerD.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view ]
    Pfami PF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56349. SSF56349. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiXERD_RICCN
    AccessioniPrimary (citable) accession number: Q92IC9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 22, 2003
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3