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Protein

Putative N-acetylmuramoyl-L-alanine amidase RC0497

Gene

RC0497

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

GO - Molecular functioni

  1. N-acetylmuramoyl-L-alanine amidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Cell wall biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Putative N-acetylmuramoyl-L-alanine amidase RC0497 (EC:3.5.1.28)
Gene namesi
Ordered Locus Names:RC0497
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 267267Putative N-acetylmuramoyl-L-alanine amidase RC0497PRO_0000279758Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0497.

Structurei

3D structure databases

ProteinModelPortaliQ92IC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3023.
HOGENOMiHOG000010748.
KOiK01447.
OMAiTQEQKSE.
OrthoDBiEOG6TJ7W3.

Family and domain databases

Gene3Di1.10.101.10. 1 hit.
3.40.80.10. 1 hit.
InterProiIPR002502. Amidase_domain.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PfamiPF01510. Amidase_2. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
SSF55846. SSF55846. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92IC3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKSKAIENN GISNTNSPNG KYMAPRPEGV KPTCVVITYS VSKDIKAVRE
60 70 80 90 100
VLDERGASVH YIIDKDGTQK EYHNDLTDQA FYAGKSSWKG EVGVNKFGIG
110 120 130 140 150
VMLINDAKSD FPAEQIGKLK EFLKDVTERY PNLDLKHDLV GLGEVTVNRE
160 170 180 190 200
GNAHIAPGSK FPWKELAEAG FGRYFETTQE QKSKLLLSLD STGEKVNTLQ
210 220 230 240 250
ENLKEYGYGV ESTSTFDQFT QQAVRVFNDR YGTGLPNEEP PVSWTEAGQD
260
VLSQLLGQTV LEQTENA
Length:267
Mass (Da):29,592
Last modified:December 1, 2001 - v1
Checksum:iF936FEBF70E673F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03035.1.
PIRiA97762.
RefSeqiNP_360134.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL03035; AAL03035; RC0497.
GeneIDi928718.
KEGGirco:RC0497.
PATRICi17888230. VBIRicCon45613_0568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03035.1.
PIRiA97762.
RefSeqiNP_360134.1. NC_003103.1.

3D structure databases

ProteinModelPortaliQ92IC3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272944.RC0497.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL03035; AAL03035; RC0497.
GeneIDi928718.
KEGGirco:RC0497.
PATRICi17888230. VBIRicCon45613_0568.

Phylogenomic databases

eggNOGiCOG3023.
HOGENOMiHOG000010748.
KOiK01447.
OMAiTQEQKSE.
OrthoDBiEOG6TJ7W3.

Family and domain databases

Gene3Di1.10.101.10. 1 hit.
3.40.80.10. 1 hit.
InterProiIPR002502. Amidase_domain.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PfamiPF01510. Amidase_2. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
SSF55846. SSF55846. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiY497_RICCN
AccessioniPrimary (citable) accession number: Q92IC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: December 1, 2001
Last modified: January 7, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.