Q92IC3 (Y497_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative N-acetylmuramoyl-L-alanine amidase RC0497
EC=3.5.1.28

Gene names

Ordered Locus Names:

RC0497

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.
Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Secreted
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	N-acetylmuramoyl-L-alanine amidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 267	267	Putative N-acetylmuramoyl-L-alanine amidase RC0497		PRO_0000279758

Sequences

	Sequence		Length	Mass (Da)
	Q92IC3 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: F936FEBF70E673F3	FASTA	267	29,592
	10 20 30 40 50 60 MSKSKAIENN GISNTNSPNG KYMAPRPEGV KPTCVVITYS VSKDIKAVRE VLDERGASVH 70 80 90 100 110 120 YIIDKDGTQK EYHNDLTDQA FYAGKSSWKG EVGVNKFGIG VMLINDAKSD FPAEQIGKLK 130 140 150 160 170 180 EFLKDVTERY PNLDLKHDLV GLGEVTVNRE GNAHIAPGSK FPWKELAEAG FGRYFETTQE 190 200 210 220 230 240 QKSKLLLSLD STGEKVNTLQ ENLKEYGYGV ESTSTFDQFT QQAVRVFNDR YGTGLPNEEP 250 260 PVSWTEAGQD VLSQLLGQTV LEQTENA

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL03035.1.
PIR	A97762.
RefSeq	NP_360134.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92IC3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL03035; AAL03035; RC0497.
GeneID	928718.
KEGG	rco:RC0497.
PATRIC	17888230. VBIRicCon45613_0568.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3023.
HOGENOM	HOG000010748.
KO	K01447.
OMA	NGKYMAP.
ProtClustDB	CLSK881993.
Family and domain databases
Gene3D	1.10.101.10. 1 hit. 3.40.80.10. 1 hit.
InterPro	IPR002502. Amidase_domain. IPR002477. Peptidoglycan-bd-like. [Graphical view]
Pfam	PF01510. Amidase_2. 1 hit. PF01471. PG_binding_1. 1 hit. [Graphical view]
SUPFAM	SSF55846. Amidase_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y497_RICCN

Accession

Primary (citable) accession number: Q92IC3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 6, 2007
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program