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Q92IC3 (Y497_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative N-acetylmuramoyl-L-alanine amidase RC0497

EC=3.5.1.28
Gene names
Ordered Locus Names:RC0497
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Ontologies

Keywords
   Biological processCell wall biogenesis/degradation
   Cellular componentSecreted
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpeptidoglycan catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionN-acetylmuramoyl-L-alanine amidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Putative N-acetylmuramoyl-L-alanine amidase RC0497
PRO_0000279758

Sequences

Sequence LengthMass (Da)Tools
Q92IC3 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: F936FEBF70E673F3

FASTA26729,592
        10         20         30         40         50         60 
MSKSKAIENN GISNTNSPNG KYMAPRPEGV KPTCVVITYS VSKDIKAVRE VLDERGASVH 

        70         80         90        100        110        120 
YIIDKDGTQK EYHNDLTDQA FYAGKSSWKG EVGVNKFGIG VMLINDAKSD FPAEQIGKLK 

       130        140        150        160        170        180 
EFLKDVTERY PNLDLKHDLV GLGEVTVNRE GNAHIAPGSK FPWKELAEAG FGRYFETTQE 

       190        200        210        220        230        240 
QKSKLLLSLD STGEKVNTLQ ENLKEYGYGV ESTSTFDQFT QQAVRVFNDR YGTGLPNEEP 

       250        260 
PVSWTEAGQD VLSQLLGQTV LEQTENA 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03035.1.
PIRA97762.
RefSeqNP_360134.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92IC3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0497.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL03035; AAL03035; RC0497.
GeneID928718.
KEGGrco:RC0497.
PATRIC17888230. VBIRicCon45613_0568.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3023.
HOGENOMHOG000010748.
KOK01447.
OMATQEQKSE.
OrthoDBEOG6TJ7W3.
ProtClustDBCLSK881993.

Family and domain databases

Gene3D1.10.101.10. 1 hit.
3.40.80.10. 1 hit.
InterProIPR002502. Amidase_domain.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PfamPF01510. Amidase_2. 1 hit.
PF01471. PG_binding_1. 1 hit.
[Graphical view]
SUPFAMSSF47090. SSF47090. 1 hit.
SSF55846. SSF55846. 1 hit.
ProtoNetSearch...

Entry information

Entry nameY497_RICCN
AccessionPrimary (citable) accession number: Q92IC3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: December 1, 2001
Last modified: March 19, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names