ID   TLCB_RICCN              Reviewed;         507 AA.
AC   Q92I98;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   RecName: Full=ADP,ATP carrier protein 2;
DE   AltName: Full=ADP/ATP translocase 2;
GN   Name=tlcB; Synonyms=tlc2; OrderedLocusNames=RC0522;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- FUNCTION: Provides the rickettsial cell with host ATP in exchange for
CC       rickettsial ADP. This is an obligate exchange system. This energy
CC       acquiring activity is an important component of rickettsial parasitism
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ADP/ATP translocase tlc family.
CC       {ECO:0000305}.
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DR   EMBL; AE006914; AAL03060.1; -; Genomic_DNA.
DR   PIR; B97765; B97765.
DR   RefSeq; WP_010977161.1; NC_003103.1.
DR   AlphaFoldDB; Q92I98; -.
DR   GeneID; 927640; -.
DR   KEGG; rco:RC0522; -.
DR   PATRIC; fig|272944.4.peg.597; -.
DR   HOGENOM; CLU_023964_0_1_5; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; IEA:InterPro.
DR   InterPro; IPR004667; ADP_ATP_car_bac_type.
DR   NCBIfam; TIGR00769; AAA; 1.
DR   PANTHER; PTHR31187; -; 1.
DR   PANTHER; PTHR31187:SF13; ADP,ATP CARRIER PROTEIN 1, CHLOROPLASTIC; 1.
DR   Pfam; PF03219; TLC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..507
FT                   /note="ADP,ATP carrier protein 2"
FT                   /id="PRO_0000286470"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        333..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        451..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        474..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   507 AA;  58365 MW;  49A92CD91E300C70 CRC64;
     MDSVDSNFTI WNKARNSKFR HIVWPIRSYE LTKFIPMALL MFFILLNQNL VRSIKDSFVV
     TLISSEVLSF IKLWGEMPMG ILFVIFYSKL CNIMTTEQVF RIITGTFLFF FAIFGFILFP
     YREFFHPDPE LIKHYITVLP HLKWFLIIWG QWSLVLFYIM GELWPVIVFT LLYWQLANKI
     TKVEEAPRFY SFFTLFGQTN LLISGTVIIY FAKSEHFLLP LFSHLNDTNE ILLKSFITVI
     LISGLICLAL HKLIDKSVVE ADKNIKFKNQ RMDILKLSLV DSAKVILTSR YLGFICLLVM
     SYSMSISLIE GLWMSKVKQL YPATKDFIAY HGKVFFWTGI LTLVSAFLGS SLIRICGWFW
     GAIITPIMMF GAGVMFFSFT VFENHLGNIV NTLGYSAPLV VIVFIGGLWH VLSKSVKYSL
     FDATKEMVYI PLDSEMKTKG KAAVDVMGAK IGKSIGAIIQ FISFSIFPNA IHNDIAGLLM
     FSFIIVCLLW LYGVKVLSKY YNKMIQR
//