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Protein

ADP,ATP carrier protein 2

Gene

tlcB

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 2
Alternative name(s):
ADP/ATP translocase 2
Gene namesi
Name:tlcB
Synonyms:tlc2
Ordered Locus Names:RC0522
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000000816 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 51HelicalSequence analysisAdd BLAST21
Transmembranei67 – 87HelicalSequence analysisAdd BLAST21
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei130 – 150HelicalSequence analysisAdd BLAST21
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Transmembranei292 – 312HelicalSequence analysisAdd BLAST21
Transmembranei333 – 353HelicalSequence analysisAdd BLAST21
Transmembranei357 – 377HelicalSequence analysisAdd BLAST21
Transmembranei393 – 413HelicalSequence analysisAdd BLAST21
Transmembranei451 – 471HelicalSequence analysisAdd BLAST21
Transmembranei474 – 494HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002864701 – 507ADP,ATP carrier protein 2Add BLAST507

Family & Domainsi

Sequence similaritiesi

Belongs to the ADP/ATP translocase tlc family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000238123.
OMAiHIVWPIR.
OrthoDBiPOG091H0NGX.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
[Graphical view]
PANTHERiPTHR31187. PTHR31187. 1 hit.
PfamiPF03219. TLC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92I98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSVDSNFTI WNKARNSKFR HIVWPIRSYE LTKFIPMALL MFFILLNQNL
60 70 80 90 100
VRSIKDSFVV TLISSEVLSF IKLWGEMPMG ILFVIFYSKL CNIMTTEQVF
110 120 130 140 150
RIITGTFLFF FAIFGFILFP YREFFHPDPE LIKHYITVLP HLKWFLIIWG
160 170 180 190 200
QWSLVLFYIM GELWPVIVFT LLYWQLANKI TKVEEAPRFY SFFTLFGQTN
210 220 230 240 250
LLISGTVIIY FAKSEHFLLP LFSHLNDTNE ILLKSFITVI LISGLICLAL
260 270 280 290 300
HKLIDKSVVE ADKNIKFKNQ RMDILKLSLV DSAKVILTSR YLGFICLLVM
310 320 330 340 350
SYSMSISLIE GLWMSKVKQL YPATKDFIAY HGKVFFWTGI LTLVSAFLGS
360 370 380 390 400
SLIRICGWFW GAIITPIMMF GAGVMFFSFT VFENHLGNIV NTLGYSAPLV
410 420 430 440 450
VIVFIGGLWH VLSKSVKYSL FDATKEMVYI PLDSEMKTKG KAAVDVMGAK
460 470 480 490 500
IGKSIGAIIQ FISFSIFPNA IHNDIAGLLM FSFIIVCLLW LYGVKVLSKY

YNKMIQR
Length:507
Mass (Da):58,365
Last modified:December 1, 2001 - v1
Checksum:i49A92CD91E300C70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03060.1.
PIRiB97765.
RefSeqiWP_010977161.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL03060; AAL03060; RC0522.
GeneIDi927640.
KEGGirco:RC0522.
PATRICi17888288. VBIRicCon45613_0597.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03060.1.
PIRiB97765.
RefSeqiWP_010977161.1. NC_003103.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL03060; AAL03060; RC0522.
GeneIDi927640.
KEGGirco:RC0522.
PATRICi17888288. VBIRicCon45613_0597.

Phylogenomic databases

HOGENOMiHOG000238123.
OMAiHIVWPIR.
OrthoDBiPOG091H0NGX.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
[Graphical view]
PANTHERiPTHR31187. PTHR31187. 1 hit.
PfamiPF03219. TLC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00769. AAA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTLCB_RICCN
AccessioniPrimary (citable) accession number: Q92I98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.