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Q92I98

- TLCB_RICCN

UniProt

Q92I98 - TLCB_RICCN

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Protein

ADP,ATP carrier protein 2

Gene

tlcB

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity).By similarity

GO - Molecular functioni

  1. ATP:ADP antiporter activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 2
Alternative name(s):
ADP/ATP translocase 2
Gene namesi
Name:tlcB
Synonyms:tlc2
Ordered Locus Names:RC0522
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei31 – 5121HelicalSequence AnalysisAdd
BLAST
Transmembranei67 – 8721HelicalSequence AnalysisAdd
BLAST
Transmembranei99 – 11921HelicalSequence AnalysisAdd
BLAST
Transmembranei130 – 15021HelicalSequence AnalysisAdd
BLAST
Transmembranei154 – 17421HelicalSequence AnalysisAdd
BLAST
Transmembranei192 – 21221HelicalSequence AnalysisAdd
BLAST
Transmembranei231 – 25121HelicalSequence AnalysisAdd
BLAST
Transmembranei292 – 31221HelicalSequence AnalysisAdd
BLAST
Transmembranei333 – 35321HelicalSequence AnalysisAdd
BLAST
Transmembranei357 – 37721HelicalSequence AnalysisAdd
BLAST
Transmembranei393 – 41321HelicalSequence AnalysisAdd
BLAST
Transmembranei451 – 47121HelicalSequence AnalysisAdd
BLAST
Transmembranei474 – 49421HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 507507ADP,ATP carrier protein 2PRO_0000286470Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0522.

Family & Domainsi

Sequence similaritiesi

Belongs to the ADP/ATP translocase tlc family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3202.
HOGENOMiHOG000238123.
OMAiHIVWPIR.
OrthoDBiEOG6BCSND.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
[Graphical view]
PfamiPF03219. TLC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92I98-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSVDSNFTI WNKARNSKFR HIVWPIRSYE LTKFIPMALL MFFILLNQNL
60 70 80 90 100
VRSIKDSFVV TLISSEVLSF IKLWGEMPMG ILFVIFYSKL CNIMTTEQVF
110 120 130 140 150
RIITGTFLFF FAIFGFILFP YREFFHPDPE LIKHYITVLP HLKWFLIIWG
160 170 180 190 200
QWSLVLFYIM GELWPVIVFT LLYWQLANKI TKVEEAPRFY SFFTLFGQTN
210 220 230 240 250
LLISGTVIIY FAKSEHFLLP LFSHLNDTNE ILLKSFITVI LISGLICLAL
260 270 280 290 300
HKLIDKSVVE ADKNIKFKNQ RMDILKLSLV DSAKVILTSR YLGFICLLVM
310 320 330 340 350
SYSMSISLIE GLWMSKVKQL YPATKDFIAY HGKVFFWTGI LTLVSAFLGS
360 370 380 390 400
SLIRICGWFW GAIITPIMMF GAGVMFFSFT VFENHLGNIV NTLGYSAPLV
410 420 430 440 450
VIVFIGGLWH VLSKSVKYSL FDATKEMVYI PLDSEMKTKG KAAVDVMGAK
460 470 480 490 500
IGKSIGAIIQ FISFSIFPNA IHNDIAGLLM FSFIIVCLLW LYGVKVLSKY

YNKMIQR
Length:507
Mass (Da):58,365
Last modified:December 1, 2001 - v1
Checksum:i49A92CD91E300C70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03060.1.
PIRiB97765.
RefSeqiNP_360159.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL03060; AAL03060; RC0522.
GeneIDi927640.
KEGGirco:RC0522.
PATRICi17888288. VBIRicCon45613_0597.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03060.1 .
PIRi B97765.
RefSeqi NP_360159.1. NC_003103.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0522.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL03060 ; AAL03060 ; RC0522 .
GeneIDi 927640.
KEGGi rco:RC0522.
PATRICi 17888288. VBIRicCon45613_0597.

Phylogenomic databases

eggNOGi COG3202.
HOGENOMi HOG000238123.
OMAi HIVWPIR.
OrthoDBi EOG6BCSND.

Family and domain databases

InterProi IPR004667. ADP_ATP_car.
[Graphical view ]
Pfami PF03219. TLC. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00769. AAA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiTLCB_RICCN
AccessioniPrimary (citable) accession number: Q92I98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3