Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q92I65

- COX2_RICCN

UniProt

Q92I65 - COX2_RICCN

Protein

Probable cytochrome c oxidase subunit 2

Gene

ctaC

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) By similarity.By similarity

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    Cofactori

    Copper A.By similarity
    Heme group.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi235 – 2351Copper ASequence Analysis
    Metal bindingi270 – 2701Copper ASequence Analysis
    Metal bindingi274 – 2741Copper ASequence Analysis
    Metal bindingi278 – 2781Copper ASequence Analysis

    GO - Molecular functioni

    1. copper ion binding Source: InterPro
    2. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    Copper, Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cytochrome c oxidase subunit 2 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 2
    Cytochrome c oxidase polypeptide II
    Gene namesi
    Name:ctaC
    Synonyms:coxB
    Ordered Locus Names:RC0555
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    3. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 315315Probable cytochrome c oxidase subunit 2PRO_0000183719Add
    BLAST

    Proteomic databases

    PRIDEiQ92I65.

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC0555.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92I65.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei54 – 7421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei96 – 11621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei133 – 15321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1622.
    HOGENOMiHOG000264988.
    KOiK02275.
    OMAiDNWIASK.
    OrthoDBiEOG68SVXT.

    Family and domain databases

    Gene3Di1.10.287.90. 1 hit.
    2.60.40.420. 1 hit.
    InterProiIPR001505. Copper_CuA.
    IPR008972. Cupredoxin.
    IPR014222. Cyt_c_oxidase_su2.
    IPR002429. Cyt_c_oxidase_su2_C.
    IPR011759. Cyt_c_oxidase_su2_TM_dom.
    IPR005728. Rickett_RPE.
    [Graphical view]
    PfamiPF00116. COX2. 1 hit.
    PF02790. COX2_TM. 1 hit.
    [Graphical view]
    SUPFAMiSSF49503. SSF49503. 1 hit.
    SSF81464. SSF81464. 1 hit.
    TIGRFAMsiTIGR02866. CoxB. 1 hit.
    TIGR01045. RPE1. 1 hit.
    PROSITEiPS00078. COX2. 1 hit.
    PS50857. COX2_CUA. 1 hit.
    PS50999. COX2_TM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92I65-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNIIRHFSK PAYREEFKED TSPRTAEYKS VSEDSSTGLT YTLPPKAKFG    50
    KMSIALICFL IVSCNCFASE PLPWQVTFQP PASPIMEELH HFHNFLLYIS 100
    TAIVLFVAGL LGFVCIRFNA KNNPVPAKFS HNVLIEIIWT VIPIIILVII 150
    AVPSFKILRH AEKIPKTDLT IKVVGYQWYW HYIYPDHDNL EFDSVMISDE 200
    NLKPNHKRLL DVDNRIVIPE NATVRFLITA GDVIHSFAVP SLGFKIDAVP 250
    GRINETWTRV AKKGVYYGQC SELCGIHHGF MPIAIEVVSK EDFDNWIASK 300
    NKTAMNGKKP KLVAN 315
    Length:315
    Mass (Da):35,744
    Last modified:December 1, 2001 - v1
    Checksum:iCBFD01EED5FF30E4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03093.1.
    PIRiC97769.
    RefSeqiNP_360192.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL03093; AAL03093; RC0555.
    GeneIDi927663.
    KEGGirco:RC0555.
    PATRICi17888366. VBIRicCon45613_0634.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03093.1 .
    PIRi C97769.
    RefSeqi NP_360192.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92I65.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0555.

    Proteomic databases

    PRIDEi Q92I65.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL03093 ; AAL03093 ; RC0555 .
    GeneIDi 927663.
    KEGGi rco:RC0555.
    PATRICi 17888366. VBIRicCon45613_0634.

    Phylogenomic databases

    eggNOGi COG1622.
    HOGENOMi HOG000264988.
    KOi K02275.
    OMAi DNWIASK.
    OrthoDBi EOG68SVXT.

    Family and domain databases

    Gene3Di 1.10.287.90. 1 hit.
    2.60.40.420. 1 hit.
    InterProi IPR001505. Copper_CuA.
    IPR008972. Cupredoxin.
    IPR014222. Cyt_c_oxidase_su2.
    IPR002429. Cyt_c_oxidase_su2_C.
    IPR011759. Cyt_c_oxidase_su2_TM_dom.
    IPR005728. Rickett_RPE.
    [Graphical view ]
    Pfami PF00116. COX2. 1 hit.
    PF02790. COX2_TM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49503. SSF49503. 1 hit.
    SSF81464. SSF81464. 1 hit.
    TIGRFAMsi TIGR02866. CoxB. 1 hit.
    TIGR01045. RPE1. 1 hit.
    PROSITEi PS00078. COX2. 1 hit.
    PS50857. COX2_CUA. 1 hit.
    PS50999. COX2_TM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiCOX2_RICCN
    AccessioniPrimary (citable) accession number: Q92I65
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3