Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q92I37

- DPO3B_RICCN

UniProt

Q92I37 - DPO3B_RICCN

Protein

DNA polymerase III subunit beta

Gene

dnaN

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA By similarity.By similarity

    Catalytic activityi

    Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

    GO - Molecular functioni

    1. 3'-5' exonuclease activity Source: InterPro
    2. DNA binding Source: InterPro
    3. DNA-directed DNA polymerase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    DNA replication

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA polymerase III subunit beta (EC:2.7.7.7)
    Gene namesi
    Name:dnaN
    Ordered Locus Names:RC0583
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. DNA polymerase III complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 379379DNA polymerase III subunit betaPRO_0000105457Add
    BLAST

    Interactioni

    Subunit structurei

    DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex By similarity.By similarity

    Protein-protein interaction databases

    STRINGi272944.RC0583.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92I37.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0592.
    HOGENOMiHOG000071791.
    KOiK02338.
    OMAiAVCSMPV.
    OrthoDBiEOG65J53F.

    Family and domain databases

    InterProiIPR001001. DNA_polIII_beta.
    IPR022635. DNA_polIII_beta_C.
    IPR022637. DNA_polIII_beta_cen.
    IPR022634. DNA_polIII_beta_N.
    [Graphical view]
    PfamiPF00712. DNA_pol3_beta. 1 hit.
    PF02767. DNA_pol3_beta_2. 1 hit.
    PF02768. DNA_pol3_beta_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
    SMARTiSM00480. POL3Bc. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00663. dnan. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q92I37-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKLIVETKT LVQSLGFASS VVEKRNVIPE YANIKLSAKD GNLELSSTNM    50
    DLYLSQKIAV QVVSEGECTV STKTLNDIVR KLPDSELTLT DLGTTGLEIK 100
    GKNCKFNLFT LPVSSFPAMD SINPEASFKI SCTDFAKIIE STKFSISLDE 150
    TRYNLNGVYL HIKDKEFCSA STDGHRLSIS WVTLEKQIKN FGVILPQKSA 200
    EEILKIVKDP KNINEDIEIL LSSNKIKFIC NENTSMLSKL IDGTFPDYST 250
    FIPESSSSKL VINRKMFADS IERIAIITVE KFRAVKLSLS RETLEISAVG 300
    EARGNAKEVI NSSQDKESFY EYNSDESLAI GFNPQYLEDV LKAVKSDVVE 350
    LYFSDVSAPV LIKFPENPKD IFVVMPVKV 379
    Length:379
    Mass (Da):42,237
    Last modified:December 1, 2001 - v1
    Checksum:i1FBE1A62CE25639C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03121.1.
    PIRiG97772.
    RefSeqiNP_360220.1. NC_003103.1.
    WP_010977217.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL03121; AAL03121; RC0583.
    GeneIDi927682.
    KEGGirco:RC0583.
    PATRICi17888428. VBIRicCon45613_0665.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03121.1 .
    PIRi G97772.
    RefSeqi NP_360220.1. NC_003103.1.
    WP_010977217.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92I37.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC0583.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL03121 ; AAL03121 ; RC0583 .
    GeneIDi 927682.
    KEGGi rco:RC0583.
    PATRICi 17888428. VBIRicCon45613_0665.

    Phylogenomic databases

    eggNOGi COG0592.
    HOGENOMi HOG000071791.
    KOi K02338.
    OMAi AVCSMPV.
    OrthoDBi EOG65J53F.

    Family and domain databases

    InterProi IPR001001. DNA_polIII_beta.
    IPR022635. DNA_polIII_beta_C.
    IPR022637. DNA_polIII_beta_cen.
    IPR022634. DNA_polIII_beta_N.
    [Graphical view ]
    Pfami PF00712. DNA_pol3_beta. 1 hit.
    PF02767. DNA_pol3_beta_2. 1 hit.
    PF02768. DNA_pol3_beta_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000804. DNA_pol_III_b. 1 hit.
    SMARTi SM00480. POL3Bc. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00663. dnan. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiDPO3B_RICCN
    AccessioniPrimary (citable) accession number: Q92I37
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 31, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names

    External Data

    Dasty 3