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Q92I31

- CDSA_RICCN

UniProt

Q92I31 - CDSA_RICCN

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Protein

Phosphatidate cytidylyltransferase

Gene
cdsA, RC0589
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:RC0589
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei33 – 5321Helical; Reviewed predictionAdd
BLAST
Transmembranei67 – 8721Helical; Reviewed predictionAdd
BLAST
Transmembranei95 – 11521Helical; Reviewed predictionAdd
BLAST
Transmembranei133 – 15321Helical; Reviewed predictionAdd
BLAST
Transmembranei167 – 18721Helical; Reviewed predictionAdd
BLAST
Transmembranei206 – 22621Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 230230Phosphatidate cytidylyltransferasePRO_0000281057Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0589.

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
HOGENOMiHOG000006169.
KOiK00981.
OMAiLNPMLEN.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92I31-1 [UniParc]FASTAAdd to Basket

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MITQKGKEHL VKDKQKSNIY LRILSGIVLV PLFVIAILWC KPLFYILMIL    50
VGTGMLSEWY NMTYSSIPDL LIGLIIIPIP ISLLIFLSME DTNRWLIMLY 100
FCIMWSVDTF AMIGGKTFKG AKLAPKLSPK KTWSGLVTGV LSAGLVAVLV 150
SFIPNFHIEN YYFSNKIYLF IISCILALIA QLSDLFISYF KRKFNIKDSG 200
HIIPGHGGVL DRFDSIILTT LILFLMKIYL 230
Length:230
Mass (Da):26,126
Last modified:December 1, 2001 - v1
Checksum:i0622FC437489188D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL03127.1.
PIRiE97773.
RefSeqiNP_360226.1. NC_003103.1.
WP_010977221.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL03127; AAL03127; RC0589.
GeneIDi927687.
KEGGirco:RC0589.
PATRICi17888448. VBIRicCon45613_0675.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL03127.1 .
PIRi E97773.
RefSeqi NP_360226.1. NC_003103.1.
WP_010977221.1. NC_003103.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0589.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL03127 ; AAL03127 ; RC0589 .
GeneIDi 927687.
KEGGi rco:RC0589.
PATRICi 17888448. VBIRicCon45613_0675.

Phylogenomic databases

eggNOGi COG0575.
HOGENOMi HOG000006169.
KOi K00981.
OMAi LNPMLEN.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiCDSA_RICCN
AccessioniPrimary (citable) accession number: Q92I31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 1, 2001
Last modified: September 3, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia conorii
    (strain Malish 7): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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