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Q92HL2 (RHO_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription termination factor Rho

EC=3.6.4.-
Alternative name(s):
ATP-dependent helicase Rho
Gene names
Name:rho
Ordered Locus Names:RC0759
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template By similarity. HAMAP-Rule MF_01884

Subunit structure

Homohexamer. The homohexamer assembles into an open ring structure By similarity.

Sequence similarities

Belongs to the Rho family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 458458Transcription termination factor Rho HAMAP-Rule MF_01884
PRO_0000286651

Regions

Nucleotide binding201 – 2066ATP Potential
Nucleotide binding213 – 2186ATP By similarity

Sites

Binding site2441ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92HL2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 6D65C3DA7FD244D6

FASTA45851,278
        10         20         30         40         50         60 
MNTTNKESTA ELNNTESNNN YNNFAENGNI INLKQLKRKL PEELQAQAEE LKIENINSLL 

        70         80         90        100        110        120 
KQELVFAILK KSVEQGVLIV GEGVLEVLPD GFGFLRSPEV NYLAGPDDIY ISPSQIRRFG 

       130        140        150        160        170        180 
LRTGDTVEGQ IRAPKAGERY FALLKVNRVN FEDPSKAYHR VHFDNLTPLY PDEKLGLELE 

       190        200        210        220        230        240 
NNSKDSKDFS TRVIELVAPM GKGQRALIVA PPRTGKTVLL QNIAHAITTN NPEVFLIVLL 

       250        260        270        280        290        300 
IDERPEEVTD MQRSVRGEVV SSTFDEPASR HVQLAEMVIK KAKRLVEHKK DVVILVDAIT 

       310        320        330        340        350        360 
RLARAYNTVV PSSGKVLTGG VDANALQRPK RFFGAARNIE NGGSLTIIGT ALIETGSRMD 

       370        380        390        400        410        420 
EVIFEEFKGT GNSEIVLDRK IADKRIYPAI DITRSGTRKE DLLVDKIILN KMWVLRRIID 

       430        440        450 
PMGSSEAIEF LLKKLENTKT NGEFFEMMKS PERPKNGL 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03297.1.
PIRG97794.
RefSeqNP_360396.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92HL2.
SMRQ92HL2. Positions 31-449.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC0759.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL03297; AAL03297; RC0759.
GeneID927486.
KEGGrco:RC0759.
PATRIC17888840. VBIRicCon45613_0863.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1158.
HOGENOMHOG000076952.
KOK03628.
OMAFGFLRAP.
OrthoDBEOG6N681W.
ProtClustDBPRK09376.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01884. Rho.
InterProIPR003593. AAA+_ATPase.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR011112. Rho_N.
IPR011113. Rho_RNA-bd.
IPR004665. Term_rho.
[Graphical view]
PfamPF00006. ATP-synt_ab. 1 hit.
PF07498. Rho_N. 1 hit.
PF07497. Rho_RNA_bind. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
SM00357. CSP. 1 hit.
SM00959. Rho_N. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF68912. SSF68912. 1 hit.
TIGRFAMsTIGR00767. rho. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRHO_RICCN
AccessionPrimary (citable) accession number: Q92HL2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: December 1, 2001
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names