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Q92HL2

- RHO_RICCN

UniProt

Q92HL2 - RHO_RICCN

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Protein

Transcription termination factor Rho

Gene

rho

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei244 – 2441ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2066ATPUniRule annotation
Nucleotide bindingi213 – 2186ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. helicase activity Source: UniProtKB-HAMAP
  3. RNA binding Source: UniProtKB-HAMAP
  4. RNA-dependent ATPase activity Source: InterPro

GO - Biological processi

  1. DNA-templated transcription, termination Source: UniProtKB-HAMAP
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Biological processi

Transcription, Transcription regulation, Transcription termination

Keywords - Ligandi

ATP-binding, Nucleotide-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination factor RhoUniRule annotation (EC:3.6.4.-UniRule annotation)
Alternative name(s):
ATP-dependent helicase RhoUniRule annotation
Gene namesi
Name:rhoUniRule annotation
Ordered Locus Names:RC0759
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 458458Transcription termination factor RhoPRO_0000286651Add
BLAST

Interactioni

Subunit structurei

Homohexamer. The homohexamer assembles into an open ring structure.UniRule annotation

Protein-protein interaction databases

STRINGi272944.RC0759.

Structurei

3D structure databases

ProteinModelPortaliQ92HL2.
SMRiQ92HL2. Positions 31-449.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Rho family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1158.
HOGENOMiHOG000076952.
KOiK03628.
OMAiTEMQRMV.
OrthoDBiEOG6N681W.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01884. Rho.
InterProiIPR003593. AAA+_ATPase.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR011112. Rho_N.
IPR011113. Rho_RNA-bd.
IPR004665. Term_rho.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 1 hit.
PF07498. Rho_N. 1 hit.
PF07497. Rho_RNA_bind. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00357. CSP. 1 hit.
SM00959. Rho_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF68912. SSF68912. 1 hit.
TIGRFAMsiTIGR00767. rho. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92HL2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNTTNKESTA ELNNTESNNN YNNFAENGNI INLKQLKRKL PEELQAQAEE
60 70 80 90 100
LKIENINSLL KQELVFAILK KSVEQGVLIV GEGVLEVLPD GFGFLRSPEV
110 120 130 140 150
NYLAGPDDIY ISPSQIRRFG LRTGDTVEGQ IRAPKAGERY FALLKVNRVN
160 170 180 190 200
FEDPSKAYHR VHFDNLTPLY PDEKLGLELE NNSKDSKDFS TRVIELVAPM
210 220 230 240 250
GKGQRALIVA PPRTGKTVLL QNIAHAITTN NPEVFLIVLL IDERPEEVTD
260 270 280 290 300
MQRSVRGEVV SSTFDEPASR HVQLAEMVIK KAKRLVEHKK DVVILVDAIT
310 320 330 340 350
RLARAYNTVV PSSGKVLTGG VDANALQRPK RFFGAARNIE NGGSLTIIGT
360 370 380 390 400
ALIETGSRMD EVIFEEFKGT GNSEIVLDRK IADKRIYPAI DITRSGTRKE
410 420 430 440 450
DLLVDKIILN KMWVLRRIID PMGSSEAIEF LLKKLENTKT NGEFFEMMKS

PERPKNGL
Length:458
Mass (Da):51,278
Last modified:December 1, 2001 - v1
Checksum:i6D65C3DA7FD244D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03297.1.
PIRiG97794.
RefSeqiNP_360396.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL03297; AAL03297; RC0759.
GeneIDi927486.
KEGGirco:RC0759.
PATRICi17888840. VBIRicCon45613_0863.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA. Translation: AAL03297.1 .
PIRi G97794.
RefSeqi NP_360396.1. NC_003103.1.

3D structure databases

ProteinModelPortali Q92HL2.
SMRi Q92HL2. Positions 31-449.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0759.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL03297 ; AAL03297 ; RC0759 .
GeneIDi 927486.
KEGGi rco:RC0759.
PATRICi 17888840. VBIRicCon45613_0863.

Phylogenomic databases

eggNOGi COG1158.
HOGENOMi HOG000076952.
KOi K03628.
OMAi TEMQRMV.
OrthoDBi EOG6N681W.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_01884. Rho.
InterProi IPR003593. AAA+_ATPase.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR011112. Rho_N.
IPR011113. Rho_RNA-bd.
IPR004665. Term_rho.
[Graphical view ]
Pfami PF00006. ATP-synt_ab. 1 hit.
PF07498. Rho_N. 1 hit.
PF07497. Rho_RNA_bind. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
SM00357. CSP. 1 hit.
SM00959. Rho_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF68912. SSF68912. 1 hit.
TIGRFAMsi TIGR00767. rho. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiRHO_RICCN
AccessioniPrimary (citable) accession number: Q92HL2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: December 1, 2001
Last modified: October 1, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3