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Q92HG8

- DNAB_RICCN

UniProt

Q92HG8 - DNAB_RICCN

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Protein

Replicative DNA helicase

Gene
dnaB, RC0803
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins By similarity.

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi229 – 2368ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: UniProtKB-KW
  3. DNA helicase activity Source: InterPro

GO - Biological processi

  1. DNA replication, synthesis of RNA primer Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Biological processi

DNA replication

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Replicative DNA helicase (EC:3.6.4.12)
Gene namesi
Name:dnaB
Ordered Locus Names:RC0803
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000816: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. primosome complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Primosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 494494Replicative DNA helicasePRO_0000102028Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272944.RC0803.

Structurei

3D structure databases

ProteinModelPortaliQ92HG8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini198 – 490293SF4 helicaseAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0305.
HOGENOMiHOG000113195.
KOiK02314.
OMAiPADQIMM.
OrthoDBiEOG6T4RW5.

Family and domain databases

Gene3Di1.10.860.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR007692. DNA_helicase_DnaB.
IPR007694. DNA_helicase_DnaB-like_C.
IPR007693. DNA_helicase_DnaB-like_N.
IPR016136. DNA_helicase_N/primase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00772. DnaB. 1 hit.
PF03796. DnaB_C. 1 hit.
[Graphical view]
SUPFAMiSSF48024. SSF48024. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00665. DnaB. 1 hit.
PROSITEiPS51199. SF4_HELICASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92HG8-1 [UniParc]FASTAAdd to Basket

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MARNKINNET NILADNEDNL PIPRVLPSNV QAEQMLLGAI LTNNELLNYV    50
SEFLRDEHFF EPIHQKIYKA IEKITEKGLT ATPITLRSML TQDELFQEVE 100
GAEYLAKLIT MSMMVINPLD YGKIIYDLAI KRNLINIGEE VVNNAYNSSL 150
EVEAKEQIEH AEAKLYDLAS EGLNEKSFTK IGISISESLA SINRAMKNND 200
HIIGISTGLI DLDNKLCGFH NSDLIILAGR PSMGKTAFAI NLALNACNNM 250
RLKNIRDNQE IQSVGFFSLE MSSEQLTTRL LSMCAEIDST SLRTGILGEE 300
KYNRLRKEAN TLSELQFFID DTPALSISAI RTRARRMKRK HNLGILFIDY 350
LQLIRGVSKS ENRVSEISEI TQGLKAIAKE LNIPVIALSQ LSRAVELRED 400
KKPMLSDLRE SGTIEQDADI VMFIYREEYY LTRKEPAAGD AKHAAWLDKL 450
NKVYNIADII VAKHRNGPVG NVPLYYDSQF SKFGNLETRT FNSN 494
Length:494
Mass (Da):55,756
Last modified:December 1, 2001 - v1
Checksum:iB7B37D3F371FA779
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL03341.1.
PIRiC97800.
RefSeqiNP_360440.1. NC_003103.1.

Genome annotation databases

EnsemblBacteriaiAAL03341; AAL03341; RC0803.
GeneIDi927662.
KEGGirco:RC0803.
PATRICi17888938. VBIRicCon45613_0912.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006914 Genomic DNA. Translation: AAL03341.1 .
PIRi C97800.
RefSeqi NP_360440.1. NC_003103.1.

3D structure databases

ProteinModelPortali Q92HG8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272944.RC0803.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL03341 ; AAL03341 ; RC0803 .
GeneIDi 927662.
KEGGi rco:RC0803.
PATRICi 17888938. VBIRicCon45613_0912.

Phylogenomic databases

eggNOGi COG0305.
HOGENOMi HOG000113195.
KOi K02314.
OMAi PADQIMM.
OrthoDBi EOG6T4RW5.

Family and domain databases

Gene3Di 1.10.860.10. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR007692. DNA_helicase_DnaB.
IPR007694. DNA_helicase_DnaB-like_C.
IPR007693. DNA_helicase_DnaB-like_N.
IPR016136. DNA_helicase_N/primase_C.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00772. DnaB. 1 hit.
PF03796. DnaB_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48024. SSF48024. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00665. DnaB. 1 hit.
PROSITEi PS51199. SF4_HELICASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-613 / Malish 7.

Entry informationi

Entry nameiDNAB_RICCN
AccessioniPrimary (citable) accession number: Q92HG8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi