Q92H91 (PLP_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Parvulin-like PPIase
EC=5.2.1.8

Alternative name(s):
Peptidyl-prolyl cis-trans isomerase plp
Rotamase plp

Gene names

Name:	plp
Ordered Locus Names:	RC0880

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptidylproline (omega=180) = peptidylproline (omega=0).
Subcellular location	Cell outer membrane By similarity.
Sequence similarities	Belongs to the PpiC/parvulin rotamase family. Contains 1 PpiC domain.

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Molecular function	Isomerase Rotamase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW protein peptidyl-prolyl isomerization Inferred from electronic annotation. Source: GOC
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 282	262	Parvulin-like PPIase		PRO_0000289285
Regions
	Domain	138 – 231	94	PpiC

Sequences

	Sequence		Length	Mass (Da)
	Q92H91 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 98CA02AF5865D535	FASTA	282	31,418
	10 20 30 40 50 60 MKKLSVIFLS VSMLSGIAFA DKDKVVATYK GGEVKESQIM KEFKPQLNLQ SGETIKNFDD 70 80 90 100 110 120 FPPQDQEKLI KIYVNNLLLK EEVAKSNITS SKEFQEKLEN AKNQLAQQEL LANYIKSNIT 130 140 150 160 170 180 DKMFDDEYNK YVGNLKGKEQ IKVAHILVKS QKEANDIKTK LSKGGNFTKL AEELSLDKAS 190 200 210 220 230 240 ASNGGVIGYI LLNQPGQLVP EFEKKAFALK VNEVSTPVKT DFGWHIIKVL EKKPVPIPTK 250 260 270 280 EEAKVTIDNI LAAEVLKKYI ADLEAKANLK IMLPKADSKA GS

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL03418.1.
PIR	H97809.
RefSeq	NP_360517.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92H91.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC0880.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL03418; AAL03418; RC0880.
GeneID	927849.
KEGG	rco:RC0880.
PATRIC	17889124. VBIRicCon45613_1003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0760.
HOGENOM	HOG000014031.
KO	K01802.
OMA	SNITDKM.
ProtClustDB	CLSK870998.
Family and domain databases
InterPro	IPR000297. PPIase_PpiC. [Graphical view]
PROSITE	PS01096. PPIC_PPIASE_1. False negative. PS50198. PPIC_PPIASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PLP_RICCN

Accession

Primary (citable) accession number: Q92H91

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program