Q92GW7 (RL4_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L4

Gene names

Name:	rplD
Ordered Locus Names:	RC1005

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity. HAMAP-Rule MF_01328 Forms part of the polypeptide exit tunnel By similarity. HAMAP-Rule MF_01328
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L4P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	50S ribosomal protein L4 HAMAP-Rule MF_01328		PRO_0000129267

Sequences

	Sequence		Length	Mass (Da)
	Q92GW7 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 00E93A67C34328F3	FASTA	207	22,975
	10 20 30 40 50 60 MKTKILSLAN EEVGEISLNE DIFAVEFIRD DIIKQVIDWQ RAKAMSGNHK TKTVSEVLGT 70 80 90 100 110 120 TKKPFKQKGT GNARQGSLRS VQMRGGGVAH GPRVRSHATK LPKKVRKLGL IHALSEKCAE 130 140 150 160 170 180 GKLLVIDSLK LDKPKTSALV NILNKFQGKS FFVIDGNEVD INFSLAAKNI YNTVIVPQIG 190 200 ANVYDIIRHE YVLLSQEAVS VLEERLR

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL03543.1.
PIR	E97825.
RefSeq	NP_360642.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92GW7.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC1005.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL03543; AAL03543; RC1005.
GeneID	928147.
KEGG	rco:RC1005.
PATRIC	17889416. VBIRicCon45613_1145.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0088.
HOGENOM	HOG000248767.
KO	K02926.
OMA	GKAHGPV.
ProtClustDB	PRK05319.
Family and domain databases
Gene3D	3.40.1370.10. 1 hit.
HAMAP	MF_01328_B. Ribosomal_L4_B.
InterPro	IPR002136. Ribosomal_L4/L1e. IPR013005. Ribosomal_L4/L1e_bac-type. IPR023574. Ribosomal_L4_dom. [Graphical view]
PANTHER	PTHR10746. PTHR10746. 1 hit.
Pfam	PF00573. Ribosomal_L4. 1 hit. [Graphical view]
SUPFAM	SSF52166. Ribosomal_L4/L1E. 1 hit.
TIGRFAMs	TIGR03953. rplD_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RL4_RICCN

Accession

Primary (citable) accession number: Q92GW7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program