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Q92GP5 (LOLD_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipoprotein-releasing system ATP-binding protein LolD

EC=3.6.3.-
Gene names
Name:lolD
Ordered Locus Names:RC1077
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE) By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification]

Contains 1 ABC transporter domain.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentATP-binding cassette (ABC) transporter complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

ATPase activity

Inferred from electronic annotation. Source: InterPro

lipoprotein transporter activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Lipoprotein-releasing system ATP-binding protein LolD
PRO_0000092456

Regions

Domain6 – 220215ABC transporter
Nucleotide binding42 – 498ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q92GP5 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 5B737E3F2D89EEA3

FASTA22124,840
        10         20         30         40         50         60 
MNNTILILKN ISKHYSQGKT IVRVLDDLNL TVNEGELIAI IGSSGSGKST LLHIAGLLDK 

        70         80         90        100        110        120 
PTKGQVIIPN SKYQKYHLIR LHYLGFIYQQ HHLLKDFTAL ENVIMPRLIS GLDQKEAIED 

       130        140        150        160        170        180 
ATKILDDLGL GKKLYNMPGE LSGGEKQRVA IARSLINKPK IILADEPTGN LDPKTTNEVF 

       190        200        210        220 
NLFLKVAREQ NTAIIMVTHN YELAHKMDKL YKLKHRLLNI A 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03615.1.
PIRE97834.
RefSeqNP_360714.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92GP5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC1077.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL03615; AAL03615; RC1077.
GeneID928225.
KEGGrco:RC1077.
PATRIC17889600. VBIRicCon45613_1233.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1136.
KOK09810.
OMATHRINHR.
OrthoDBEOG6T7N3V.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015854. ABC_transpr_LolD.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51244. LOLD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLOLD_RICCN
AccessionPrimary (citable) accession number: Q92GP5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names