Q92GP5 (LOLD_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Lipoprotein-releasing system ATP-binding protein LolD
EC=3.6.3.-

Gene names

Name:	lolD
Ordered Locus Names:	RC1077

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE) By similarity.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro lipoprotein transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Lipoprotein-releasing system ATP-binding protein LolD		PRO_0000092456
Regions
	Domain	6 – 220	215	ABC transporter
	Nucleotide binding	42 – 49	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q92GP5 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 5B737E3F2D89EEA3	FASTA	221	24,840
	10 20 30 40 50 60 MNNTILILKN ISKHYSQGKT IVRVLDDLNL TVNEGELIAI IGSSGSGKST LLHIAGLLDK 70 80 90 100 110 120 PTKGQVIIPN SKYQKYHLIR LHYLGFIYQQ HHLLKDFTAL ENVIMPRLIS GLDQKEAIED 130 140 150 160 170 180 ATKILDDLGL GKKLYNMPGE LSGGEKQRVA IARSLINKPK IILADEPTGN LDPKTTNEVF 190 200 210 220 NLFLKVAREQ NTAIIMVTHN YELAHKMDKL YKLKHRLLNI A

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL03615.1.
PIR	E97834.
RefSeq	NP_360714.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92GP5.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC1077.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL03615; AAL03615; RC1077.
GeneID	928225.
KEGG	rco:RC1077.
PATRIC	17889600. VBIRicCon45613_1233.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1136.
KO	K09810.
OMA	ELAHKMD.
ProtClustDB	CLSK871039.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR015854. ABC_transpr_LolD. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51244. LOLD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOLD_RICCN

Accession

Primary (citable) accession number: Q92GP5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	December 1, 2001
Last modified:	May 29, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program