Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q92GI2 (HLYC_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Hemolysin C homolog
Gene names
Name:tlyC
Ordered Locus Names:RC1141
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Miscellaneous

Despite the presence of the tlyC gene, the true SFG rickettsiae are non-hemolytic.

Sequence similarities

Belongs to the UPF0053 family. Hemolysin C subfamily.

Contains 2 CBS domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Hemolysin C homolog
PRO_0000319030

Regions

Domain80 – 14263CBS 1
Domain145 – 20258CBS 2

Sequences

Sequence LengthMass (Da)Tools
Q92GI2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 068DA787C61C5FF4

FASTA29933,924
        10         20         30         40         50         60 
MLKSSKKEDS SKKNQNNKLI FTVRKLFSPI KNFFRKTKTP DNFFGVIKRL KINSQKMTLD 

        70         80         90        100        110        120 
ERNILANLLE LEDKTIEDIM VPRSDIAAIK LTTNLEELSE SIKLEVPHTR TLIYDGTLDN 

       130        140        150        160        170        180 
VVGFIHIKDL FKALATKQNG RLKKLIRKHI IAAPSMKLLD LLAKMRRERT HIAIVVDEYG 

       190        200        210        220        230        240 
GTDGLVTIED LIEEIVGRID DEHDQQLDSD NFKVINNSTI IANARVEVEV LEEIIGEKLH 

       250        260        270        280        290 
NDYDEFDTIG GLVLTRVSSV PAIGTRIDIS ENIEIEVTDA TPRSLKQVKI RLKNGLNGQ 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03679.1.
PIRE97842.
RefSeqNP_360778.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92GI2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272944.RC1141.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL03679; AAL03679; RC1141.
GeneID928291.
KEGGrco:RC1141.
PATRIC17889766. VBIRicCon45613_1315.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1253.
HOGENOMHOG000062294.
OMADERDNIA.
OrthoDBEOG60W7V4.
ProtClustDBCLSK871055.

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR000644. CBS_dom.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR005170. Transptr-assoc_dom.
[Graphical view]
PfamPF00571. CBS. 1 hit.
PF03471. CorC_HlyC. 1 hit.
[Graphical view]
SMARTSM00116. CBS. 2 hits.
SM01091. CorC_HlyC. 1 hit.
[Graphical view]
SUPFAMSSF56176. SSF56176. 1 hit.
PROSITEPS51371. CBS. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHLYC_RICCN
AccessionPrimary (citable) accession number: Q92GI2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 1, 2001
Last modified: November 13, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

Rickettsia conorii

(strain Malish 7): entries and gene names