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Protein

Hemolysin C homolog

Gene

tlyC

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Miscellaneous

Despite the presence of the tlyC gene, the true SFG rickettsiae are non-hemolytic.

GO - Molecular functioni

Enzyme and pathway databases

BioCyciRCON272944:G1FZG-1842-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Hemolysin C homolog
Gene namesi
Name:tlyC
Ordered Locus Names:RC1141
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000000816 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003190301 – 299Hemolysin C homologAdd BLAST299

Structurei

3D structure databases

ProteinModelPortaliQ92GI2
SMRiQ92GI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini80 – 142CBS 1PROSITE-ProRule annotationAdd BLAST63
Domaini145 – 202CBS 2PROSITE-ProRule annotationAdd BLAST58

Sequence similaritiesi

Belongs to the UPF0053 family. Hemolysin C subfamily.Curated

Keywords - Domaini

CBS domain, Repeat

Phylogenomic databases

HOGENOMiHOG000062294
OMAiERRHMAL
OrthoDBiPOG091H025R

Family and domain databases

InterProiView protein in InterPro
IPR000644 CBS_dom
IPR036318 FAD-bd_2-like_sf
IPR005170 Transptr-assoc_dom
PfamiView protein in Pfam
PF00571 CBS, 1 hit
PF03471 CorC_HlyC, 1 hit
SMARTiView protein in SMART
SM01091 CorC_HlyC, 1 hit
SUPFAMiSSF56176 SSF56176, 1 hit
PROSITEiView protein in PROSITE
PS51371 CBS, 2 hits

Sequencei

Sequence statusi: Complete.

Q92GI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKSSKKEDS SKKNQNNKLI FTVRKLFSPI KNFFRKTKTP DNFFGVIKRL
60 70 80 90 100
KINSQKMTLD ERNILANLLE LEDKTIEDIM VPRSDIAAIK LTTNLEELSE
110 120 130 140 150
SIKLEVPHTR TLIYDGTLDN VVGFIHIKDL FKALATKQNG RLKKLIRKHI
160 170 180 190 200
IAAPSMKLLD LLAKMRRERT HIAIVVDEYG GTDGLVTIED LIEEIVGRID
210 220 230 240 250
DEHDQQLDSD NFKVINNSTI IANARVEVEV LEEIIGEKLH NDYDEFDTIG
260 270 280 290
GLVLTRVSSV PAIGTRIDIS ENIEIEVTDA TPRSLKQVKI RLKNGLNGQ
Length:299
Mass (Da):33,924
Last modified:December 1, 2001 - v1
Checksum:i068DA787C61C5FF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL03679.1
PIRiE97842
RefSeqiWP_010977712.1, NC_003103.1

Genome annotation databases

EnsemblBacteriaiAAL03679; AAL03679; RC1141
GeneIDi928291
KEGGirco:RC1141
PATRICifig|272944.4.peg.1315

Similar proteinsi

Entry informationi

Entry nameiHLYC_RICCN
AccessioniPrimary (citable) accession number: Q92GI2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health