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Q92GI2

- HLYC_RICCN

UniProt

Q92GI2 - HLYC_RICCN

Protein

Hemolysin C homolog

Gene

tlyC

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenyl nucleotide binding Source: InterPro
    2. flavin adenine dinucleotide binding Source: InterPro
    3. oxidoreductase activity, acting on CH-OH group of donors Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hemolysin C homolog
    Gene namesi
    Name:tlyC
    Ordered Locus Names:RC1141
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 299299Hemolysin C homologPRO_0000319030Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272944.RC1141.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92GI2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini80 – 14263CBS 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini145 – 20258CBS 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UPF0053 family. Hemolysin C subfamily.Curated
    Contains 2 CBS domains.PROSITE-ProRule annotation

    Keywords - Domaini

    CBS domain, Repeat

    Phylogenomic databases

    eggNOGiCOG1253.
    HOGENOMiHOG000062294.
    OMAiRSNRNHI.
    OrthoDBiEOG60W7V4.

    Family and domain databases

    Gene3Di3.30.465.10. 1 hit.
    InterProiIPR000644. CBS_dom.
    IPR016169. CO_DH_flavot_FAD-bd_sub2.
    IPR016166. FAD-bd_2.
    IPR005170. Transptr-assoc_dom.
    [Graphical view]
    PfamiPF00571. CBS. 1 hit.
    PF03471. CorC_HlyC. 1 hit.
    [Graphical view]
    SMARTiSM00116. CBS. 2 hits.
    SM01091. CorC_HlyC. 1 hit.
    [Graphical view]
    SUPFAMiSSF56176. SSF56176. 1 hit.
    PROSITEiPS51371. CBS. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92GI2-1 [UniParc]FASTAAdd to Basket

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    MLKSSKKEDS SKKNQNNKLI FTVRKLFSPI KNFFRKTKTP DNFFGVIKRL    50
    KINSQKMTLD ERNILANLLE LEDKTIEDIM VPRSDIAAIK LTTNLEELSE 100
    SIKLEVPHTR TLIYDGTLDN VVGFIHIKDL FKALATKQNG RLKKLIRKHI 150
    IAAPSMKLLD LLAKMRRERT HIAIVVDEYG GTDGLVTIED LIEEIVGRID 200
    DEHDQQLDSD NFKVINNSTI IANARVEVEV LEEIIGEKLH NDYDEFDTIG 250
    GLVLTRVSSV PAIGTRIDIS ENIEIEVTDA TPRSLKQVKI RLKNGLNGQ 299
    Length:299
    Mass (Da):33,924
    Last modified:December 1, 2001 - v1
    Checksum:i068DA787C61C5FF4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03679.1.
    PIRiE97842.
    RefSeqiNP_360778.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL03679; AAL03679; RC1141.
    GeneIDi928291.
    KEGGirco:RC1141.
    PATRICi17889766. VBIRicCon45613_1315.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03679.1 .
    PIRi E97842.
    RefSeqi NP_360778.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92GI2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC1141.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL03679 ; AAL03679 ; RC1141 .
    GeneIDi 928291.
    KEGGi rco:RC1141.
    PATRICi 17889766. VBIRicCon45613_1315.

    Phylogenomic databases

    eggNOGi COG1253.
    HOGENOMi HOG000062294.
    OMAi RSNRNHI.
    OrthoDBi EOG60W7V4.

    Family and domain databases

    Gene3Di 3.30.465.10. 1 hit.
    InterProi IPR000644. CBS_dom.
    IPR016169. CO_DH_flavot_FAD-bd_sub2.
    IPR016166. FAD-bd_2.
    IPR005170. Transptr-assoc_dom.
    [Graphical view ]
    Pfami PF00571. CBS. 1 hit.
    PF03471. CorC_HlyC. 1 hit.
    [Graphical view ]
    SMARTi SM00116. CBS. 2 hits.
    SM01091. CorC_HlyC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56176. SSF56176. 1 hit.
    PROSITEi PS51371. CBS. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiHLYC_RICCN
    AccessioniPrimary (citable) accession number: Q92GI2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Despite the presence of the tlyC gene, the true SFG rickettsiae are non-hemolytic.

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families
    3. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries

    External Data

    Dasty 3