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Q92GH5 (GLRX2_RICCN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable monothiol glutaredoxin-2
Gene names
Name:grxC2
Synonyms:grlA
Ordered Locus Names:RC1148
OrganismRickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]
Taxonomic identifier272944 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group

Protein attributes

Sequence length107 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the glutaredoxin family. Monothiol subfamily.

Contains 1 glutaredoxin domain.

Sequence caution

The sequence AAL03686.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 107107Probable monothiol glutaredoxin-2
PRO_0000102264

Regions

Domain7 – 107101Glutaredoxin
Region86 – 872Glutathione binding By similarity

Sites

Metal binding321Iron-sulfur (2Fe-2S); shared with dimeric partner By similarity
Binding site241Glutathione By similarity
Binding site611Glutathione By similarity
Binding site731Glutathione; via amide nitrogen and carbonyl oxygen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92GH5 [UniParc].

Last modified July 19, 2004. Version 2.
Checksum: 1A1C15F03C29D939

FASTA10712,268
        10         20         30         40         50         60 
MLENKNFKFI ENEIKNNKVV LFMKGIKKSP ACGFSGTVVA ILNKLGVEFR DINVLFDAEL 

        70         80         90        100 
REDLKKFSDW PTFPQLYING ELVGGCDIAR ELYQSGELEK MLKAYTR 

« Hide

References

[1]"Mechanisms of evolution in Rickettsia conorii and R. prowazekii."
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.
Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006914 Genomic DNA. Translation: AAL03686.1. Different initiation.
PIRD97843.
RefSeqNP_360785.1. NC_003103.1.

3D structure databases

ProteinModelPortalQ92GH5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID928288.
GenomeReviewsGene locus RC1148 in contig AE006914_GR.
KEGGrco:RC1148.
PATRIC17889780. VBIRicCon45613_1322.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMANGELEKM.
ProtClustDBCLSK871057.

Enzyme and pathway databases

BioCycRCON272944:RC1148-MONOMER.

Family and domain databases

InterProIPR002109. Glutaredoxin.
IPR014434. Monothiol_GRX.
IPR004480. Monothiol_GRX-rel.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
Gene3DG3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KOK07390.
PANTHERPTHR10293. Glutredox-rel. 1 hit.
PfamPF00462. Glutaredoxin. 1 hit.
[Graphical view]
PIRSFPIRSF005894. Monothiol_GRX. 1 hit.
SUPFAMSSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMsTIGR00365. TIGR00365. 1 hit.
PROSITEPS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLRX2_RICCN
AccessionPrimary (citable) accession number: Q92GH5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia conorii

(strain Malish 7): entries and gene names

SIMILARITY comments

Index of protein domains and families