Reviewed, UniProtKB/Swiss-Prot Q92GH5 (GLRX2_RICCN)

Names and origin

Protein names

Recommended name:
    Probable monothiol glutaredoxin-2

Gene names

Name:	grxC2
Synonyms:	grlA
Ordered Locus Names:	RC1148

Organism

Rickettsia conorii [Complete proteome] [HAMAP]

Taxonomic identifier

781 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	107 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the glutaredoxin family. Monothiol subfamily. Contains 1 glutaredoxin domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Domain	Redox-active center
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 107	107	Probable monothiol glutaredoxin-2		PRO_0000102264
Regions
	Domain	7 – 107	101	Glutaredoxin
Sites
	Active site	32	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q92GH5-1 [UniParc]. Last modified July 19, 2004. Version 2. Checksum: 1A1C15F03C29D939	FASTA	107	12,268
	10 20 30 40 50 60 MLENKNFKFI ENEIKNNKVV LFMKGIKKSP ACGFSGTVVA ILNKLGVEFR DINVLFDAEL 70 80 90 100 REDLKKFSDW PTFPQLYING ELVGGCDIAR ELYQSGELEK MLKAYTR

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE006914 Genomic DNA. Translation: AAL03686.1. Different initiation.
PIR	D97843.
RefSeq	NP_360785.1.
3D structure databases
HSSP	HSSP built from PDB template 1B4Q based on UniProtKB P35754.
ModBase	Search...
Genome annotation databases
GeneID	928288.
GenomeReviews	Gene locus RC1148 in contig AE006914_GR.
KEGG	rco:RC1148.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q92GH5.
Enzyme and pathway databases
BioCyc	RCON272944:RC1148-MON.
Family and domain databases
InterPro	IPR002109. Glutaredoxin. IPR004480. Glutredox-rel. IPR014434. Monothiol_GRX. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PANTHER	PTHR10293. Glutredox-rel. 1 hit.
Pfam	PF00462. Glutaredoxin. 1 hit. [Graphical view]
PIRSF	PIRSF005894. Monothiol_GRX. 1 hit.
TIGRFAMs	TIGR00365. Glutredox-rel. 1 hit.
PROSITE	PS51354. GLUTAREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLRX2_RICCN

Accession

Primary (citable) accession number: Q92GH5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	June 16, 2009
This is version 36 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)