Q92GE1 (RECA_RICCN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein RecA

Alternative name(s):
Recombinase A

Gene names

Name:	recA
Ordered Locus Names:	RC1182

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7) [Complete proteome] [HAMAP]

Taxonomic identifier

272944 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia conorii

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity. HAMAP-Rule MF_00268
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the RecA family.
Sequence caution	The sequence AAL03720.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA-dependent ATPase activity Inferred from electronic annotation. Source: HAMAP damaged DNA binding Inferred from electronic annotation. Source: HAMAP single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Protein RecA HAMAP-Rule MF_00268		PRO_0000122821
Regions
	Nucleotide binding	66 – 73	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q92GE1 [UniParc]. Last modified April 16, 2002. Version 2. Checksum: C00649998931B6F2	FASTA	343	37,250
	10 20 30 40 50 60 MSNTDKERAI AAALAQIEKS YGKGSVMKLG QRPHVDIEAV STGSLGLDIA LGIGGVPKGR 70 80 90 100 110 120 IIEIFGPESS GKTTLTLHLI AEAQKKGGTC AFIDAEHALD PAYAKKLGVN IDELIISQPD 130 140 150 160 170 180 TGEQALEIAD TLIRSSGIDM IIIDSVAALV PKSEIEGEMG DAQMASQARL MSQALRKLTA 190 200 210 220 230 240 SINRTNCITV FINQIRMKIG VMFGSPETTT GGNALKFYAS VRIDIRRIGS IKDKEEVIGS 250 260 270 280 290 300 QTKVKVVKNK VSPPFKTADF DIMYGSGISK EGEIIDLGVK LDIVEKSGSW FSYKNVRIGQ 310 320 330 340 GRENVKQYLK EHPQISNEIE KIIREKSSKI TNINLDQTEE END

References

[1]

"Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006914 Genomic DNA. Translation: AAL03720.1. Different initiation.
PIR	F97847.
RefSeq	NP_360819.1. NC_003103.1.
3D structure databases
ProteinModelPortal	Q92GE1.
SMR	Q92GE1. Positions 3-341.
ModBase	Search...
Protein-protein interaction databases
STRING	272944.RC1182.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL03720; AAL03720; RC1182.
GeneID	928333.
KEGG	rco:RC1182.
PATRIC	17889854. VBIRicCon45613_1359.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0468.
HOGENOM	HOG000264120.
KO	K03553.
OMA	IRRTEWI.
ProtClustDB	PRK09354.
Family and domain databases
Gene3D	3.30.250.10. 1 hit.
HAMAP	MF_00268. RecA.
InterPro	IPR003593. AAA+_ATPase. IPR013765. DNA_recomb/repair_RecA. IPR020584. DNA_recomb/repair_RecA_CS. IPR020588. DNA_recomb_RecA/RadB_ATP-bd. IPR023400. RecA_C. IPR020587. RecA_monomer-monomer_interface. [Graphical view]
PANTHER	PTHR22942:SF1. PTHR22942:SF1. 1 hit.
Pfam	PF00154. RecA. 1 hit. [Graphical view]
PRINTS	PR00142. RECA.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF54752. SSF54752. 1 hit.
TIGRFAMs	TIGR02012. tigrfam_recA. 1 hit.
PROSITE	PS00321. RECA_1. 1 hit. PS50162. RECA_2. 1 hit. PS50163. RECA_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECA_RICCN

Accession

Primary (citable) accession number: Q92GE1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 16, 2002
Last sequence update:	April 16, 2002
Last modified:	May 1, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program