Reviewed,
UniProtKB/Swiss-Prot Q92G53 (PLD_RICCN)
Last modified
November 3, 2009.
Version 42.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Phospholipase D Short name=PLD EC=3.1.4.4 Alternative name(s): Choline phosphatase | ||||
| Gene names |
| ||||
| Organism | Rickettsia conorii [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 781 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group |
Protein attributes
| Sequence length | 200 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Could be a virulence factor. Ref.2 |
| Catalytic activity | A phosphatidylcholine + H2O = choline + a phosphatidate. Ref.2 |
| Subunit structure | Homodimer. Ref.2 |
| Subcellular location | Secreted Potential. |
| Sequence similarities | Belongs to the phospholipase D family. Contains 1 PLD phosphodiesterase domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Lipid degradation Virulence |
| Cellular component | Secreted |
| Domain | Signal |
| Molecular function | Hydrolase |
| Technical term | Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | lipid catabolic process Inferred from electronic annotation. Source: UniProtKB-KW pathogenesisInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | NAPE-specific phospholipase D activity Inferred from electronic annotation. Source: EC phospholipase D activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Mechanisms of evolution in Rickettsia conorii and R. prowazekii." Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D. Science 293:2093-2098(2001) [PubMed: 11557893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-613 / Malish 7. |
| [2] | "Identification and characterization of a phospholipase D-superfamily gene in Rickettsiae." Renesto P., Dehoux P., Gouin E., Touqui L., Cossart P., Raoult D. J. Infect. Dis. 188:1276-1283(2003) [PubMed: 14593584] [Abstract] Cited for: PROTEIN SEQUENCE OF 58-77, FUNCTION, SUBUNIT, CATALYTIC ACTIVITY. Strain: ATCC VR-613 / Malish 7. |
Cross-references
Sequence databases | |
|---|---|
| AE006914 Genomic DNA. Translation: AAL03808.1. | |
| PIR | F97858. |
| RefSeq | NP_360907.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1BYR based on UniProtKB Q46707. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 928420. |
| GenomeReviews | Gene locus RC1270 in contig AE006914_GR. |
| KEGG | rco:RC1270. |
| NMPDR | fig|272944.1.peg.1270. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q92G53. |
| OMA | TVPGIAH. |
Enzyme and pathway databases | |
| BioCyc | RCON272944:RC1270-MON. |
| BRENDA | 3.1.4.4. 267518. |
Family and domain databases | |
| InterPro | IPR001736. PLipase_D/transphosphatidylase. [Graphical view] |
| SMART | SM00155. PLDc. 1 hit. [Graphical view] |
| PROSITE | PS50035. PLD. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PLD_RICCN | ||||||||
| Accession | Primary (citable) accession number: Q92G53 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Rickettsia conorii (strain Malish 7): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


