Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q92G31

- UVRA_RICCN

UniProt

Q92G31 - UVRA_RICCN

Protein

UvrABC system protein A

Gene

uvrA

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi35 – 428ATPUniRule annotation
    Nucleotide bindingi654 – 6618ATPUniRule annotation
    Zinc fingeri754 – 78027C4-typeUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATPase activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. DNA binding Source: UniProtKB-HAMAP
    4. excinuclease ABC activity Source: UniProtKB-HAMAP
    5. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nuclease

    Keywords - Biological processi

    DNA damage, DNA excision, DNA repair, SOS response

    Keywords - Ligandi

    ATP-binding, DNA-binding, Metal-binding, Nucleotide-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein AUniRule annotation
    Short name:
    UvrA proteinUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit AUniRule annotation
    Gene namesi
    Name:uvrAUniRule annotation
    Ordered Locus Names:RC1294
    OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
    Taxonomic identifieri272944 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000816: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 955955UvrABC system protein APRO_0000093083Add
    BLAST

    Interactioni

    Subunit structurei

    Forms a heterotetramer with UvrB during the search for lesions.UniRule annotation

    Protein-protein interaction databases

    STRINGi272944.RC1294.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92G31.
    SMRiQ92G31. Positions 6-954.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini322 – 601280ABC transporter 1UniRule annotationAdd
    BLAST
    Domaini621 – 951331ABC transporter 2UniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. UvrA family.UniRule annotation
    Contains 2 ABC transporter domains.UniRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri754 – 78027C4-typeUniRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG0178.
    HOGENOMiHOG000050448.
    KOiK03701.
    OMAiEGVLNNM.
    OrthoDBiEOG6QK4PS.

    Family and domain databases

    Gene3Di3.30.1490.20. 2 hits.
    3.40.50.300. 4 hits.
    HAMAPiMF_00205. UvrA.
    InterProiIPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR013815. ATP_grasp_subdomain_1.
    IPR027417. P-loop_NTPase.
    IPR004602. UvrA.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 3 hits.
    TIGRFAMsiTIGR00630. uvra. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 2 hits.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92G31-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIMNQEYIKV RGAKEHNLKN INVNIPRNKF VVITGLSGSG KSSLAFDTIY    50
    AEGQRRYVES LSSYARQFLH LQNKPNVESI SGLSPAIAID QKTTSKNPRS 100
    TVGTITEIYD YLRLLYARVG IPYSPATGLP IHSQTVSEMV DIINELPKGT 150
    KIYLLAPIVR GHKGEFKREI MDLKKQGFQK LIVNGEVCEI DDLPKLDKNK 200
    KHNIEVIVDR IVLDESLGNR LADSLESSLN LAEGITYLEI VELPPAVKSE 250
    FEKNQRITFS EQYSCPVSGF QLTEIEPRIF SFNSPFGACP KCEGIGKEFF 300
    FDRDLIVPDQ RIAIKDGAIV PWGSTASKFI LETLKALADH YKFSIEVPFV 350
    SLSQNVKDIL FEGSGEEAIK FEFHDGSKTQ IIKQPFAGII PSLQEKDRTI 400
    ESVLIKEELA KFKSEHKCTA CSGFRLKDEA LCVKIANLHI GEVAGMSIAA 450
    LQKWFSHLEE KLNKKQLFIA ERILKEITER LKFLMNVGLD YLTLSREAGT 500
    LSGGESQRIR LASQIGSGLS GVLYVLDEPS IGLHQRDNTR LIETLKRLRD 550
    LGNTVLVVEH DEETIYEADH IIDIGPGAGI HGGRVIAEGN VEEIKNFEES 600
    ITGRYLSGRQ TIKVPSETRV GHDNRAIELL GAVSNNLDNV DIKIPLGTFT 650
    AITGVSGSGK SSLMIHTLYK AALKHLEPTS KVFPGKYREL KGLEYIDKII 700
    DINQSPIGRT PRSNPATYTG AFTHIRDWFV ELPESKARGY KVGRFSFNVK 750
    GGRCEACQGD GLIKIEMHFL PDVYVKCDIC NGHRYNRETL EIKYKGKSIA 800
    DILMMTVEDA MQFFEKIPLI YEKLITLNEV GLGYIKIGQS ATTLSGGEAQ 850
    RVKLAKELSR RSTGKTLYIL DEPTTGLHID DINKLLKVLH KLVDMGNTVL 900
    VIEHNLDVIK TADYIIDVGP EGGDKGGKIV VCGTPADIAA CEESHTGRYL 950
    KQYLV 955
    Length:955
    Mass (Da):106,317
    Last modified:December 1, 2001 - v1
    Checksum:i70ED64A253D7FA68
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03832.1.
    PIRiF97861.
    RefSeqiNP_360931.1. NC_003103.1.

    Genome annotation databases

    EnsemblBacteriaiAAL03832; AAL03832; RC1294.
    GeneIDi928444.
    KEGGirco:RC1294.
    PATRICi17890112. VBIRicCon45613_1486.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006914 Genomic DNA. Translation: AAL03832.1 .
    PIRi F97861.
    RefSeqi NP_360931.1. NC_003103.1.

    3D structure databases

    ProteinModelPortali Q92G31.
    SMRi Q92G31. Positions 6-954.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272944.RC1294.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL03832 ; AAL03832 ; RC1294 .
    GeneIDi 928444.
    KEGGi rco:RC1294.
    PATRICi 17890112. VBIRicCon45613_1486.

    Phylogenomic databases

    eggNOGi COG0178.
    HOGENOMi HOG000050448.
    KOi K03701.
    OMAi EGVLNNM.
    OrthoDBi EOG6QK4PS.

    Family and domain databases

    Gene3Di 3.30.1490.20. 2 hits.
    3.40.50.300. 4 hits.
    HAMAPi MF_00205. UvrA.
    InterProi IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR013815. ATP_grasp_subdomain_1.
    IPR027417. P-loop_NTPase.
    IPR004602. UvrA.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 3 hits.
    TIGRFAMsi TIGR00630. uvra. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 2 hits.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-613 / Malish 7.

    Entry informationi

    Entry nameiUVRA_RICCN
    AccessioniPrimary (citable) accession number: Q92G31
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 26, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia conorii
      (strain Malish 7): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3