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Q92EU4 (TPIS2_LISIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Triosephosphate isomerase 2
Short name=TIM 2
EC=5.3.1.1
Alternative name(s):
Triose-phosphate isomerase 2
Gene names
Name:tpiA2
Ordered Locus Names:lin0364
OrganismListeria innocua [Complete proteome] [HAMAP]
Taxonomic identifier1642 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate = glycerone phosphate. HAMAP MF_00147_B

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00147_B

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. HAMAP MF_00147_B

Subunit structure

Homodimer By similarity. HAMAP MF_00147_B

Subcellular location

Cytoplasm By similarity HAMAP MF_00147_B.

Sequence similarities

Belongs to the triosephosphate isomerase family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
Pentose shunt
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiontriose-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 254254Triosephosphate isomerase 2 HAMAP MF_00147_B
PRO_0000090239

Sites

Active site961Electrophile By similarity
Active site1681Proton acceptor By similarity
Binding site91Substrate By similarity
Binding site111Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92EU4 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: F99CA128F50DE71C

FASTA25428,065
        10         20         30         40         50         60 
MRKPLVGINM KNYINTRAQT SEWLEATIPL LENFSDVDTF IFPSMGTLET TANLLAGTSF 

        70         80         90        100        110        120 
GFGPQNMAPE KSGPLTGEFS VESIIDLNAN YVEIGHAERK NLFHEKTSEI AKKIKLALDE 

       130        140        150        160        170        180 
KITPVVCVGE EVHANDTNEL KNALKKQIEA LFQTINLAQW ENVVLAYEPE WAIGKASSAE 

       190        200        210        220        230        240 
TNYIESAHQA LREIIRELGG DETLVRIIYG GSVSKENAAE IVRQKNVDGL FVGRFGHKPQ 

       250 
NFADIVSIVS KTKG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL596164 Genomic DNA. Translation: CAC95597.1.
PIRAE1478.
RefSeqNP_469709.1. NC_003212.1.

3D structure databases

ProteinModelPortalQ92EU4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1128795.
GenomeReviewsGene locus lin0364 in contig AL592022_GR.
KEGGlin:lin0364.
NMPDRfig|272626.1.peg.362.
PATRIC20297410. VBILisInn102668_0379.

Organism-specific databases

GenoListLIN0364.
CMRSearch...

Phylogenomic databases

HOGENOMHBG708281.
OMAYINTRAQ.
ProtClustDBCLSK563877.

Enzyme and pathway databases

BioCycLINN272626:LIN0364-MONOMER.

Family and domain databases

HAMAPMF_00147_B. TIM_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01803.
PANTHERPTHR21139. Triophos_ismrse. 1 hit.
PfamPF00121. TIM. 1 hit.
[Graphical view]
SUPFAMSSF51351. Triophos_ismrse. 1 hit.
PROSITEPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPIS2_LISIN
AccessionPrimary (citable) accession number: Q92EU4
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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