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Q92EG6 (AROD_LISIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate dehydratase
Short name=3-dehydroquinase
EC=4.2.1.10
Alternative name(s):
Type I DHQase
Gene names
Name:aroD
Ordered Locus Names:lin0494
OrganismListeria innocua [Complete proteome] [HAMAP]
Taxonomic identifier1642 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214

Subunit structure

Homodimer By similarity. HAMAP MF_00214

Sequence similarities

Belongs to the type-I 3-dehydroquinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function3-dehydroquinate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2522523-dehydroquinate dehydratase HAMAP MF_00214
PRO_0000138799

Sites

Active site1431Proton acceptor By similarity
Active site1701Schiff-base intermediate with substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92EG6 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: E6E7F36A6DF365CC

FASTA25227,501
        10         20         30         40         50         60 
MNKVVVKNVT FGEGAPKICV PMVGKTVAAL KEEAEMLKTI DLDVVEWRVD FFEDVKDLVK 

        70         80         90        100        110        120 
VKAALDEIRA ILPETPILFT FRSAKEGGEL AVSDEFYFEL NETLAGTGKI DLVDVELFNE 

       130        140        150        160        170        180 
EADVLRLIET AHKNNVKVVM SNHDFDKTPA KEEIVSRLTR MEALGADLPK IAVMPKSAGD 

       190        200        210        220        230        240 
VLTLLDATNT VSEKANQPII TMSMAGTGVI SRLAGEVFGS AMTFGAAKKA SAPGQIDVNE 

       250 
LRHVLDLLHK QF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL596165 Genomic DNA. Translation: CAC95726.1.
PIRAF1494.
RefSeqNP_469837.1. NC_003212.1.

3D structure databases

ProteinModelPortalQ92EG6.
SMRQ92EG6. Positions 1-250.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1128944.
GenomeReviewsGene locus lin0494 in contig AL592022_GR.
KEGGlin:lin0494.
NMPDRfig|272626.1.peg.490.
PATRIC20297683. VBILisInn102668_0515.

Organism-specific databases

GenoListLIN0494.
CMRSearch...

Phylogenomic databases

HOGENOMHBG732926.
OMAIAKIAVM.
ProtClustDBPRK02412.

Enzyme and pathway databases

BioCycLINN272626:LIN0494-MONOMER.

Family and domain databases

HAMAPMF_00214. AroD.
[Tree]
InterProIPR018508. 3-dehydroquinate_DH_AS.
IPR013785. Aldolase_TIM.
IPR001381. DHquinase_I.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK03785.
PfamPF01487. DHquinase_I. 1 hit.
[Graphical view]
TIGRFAMsTIGR01093. AroD. 1 hit.
PROSITEPS01028. DEHYDROQUINASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROD_LISIN
AccessionPrimary (citable) accession number: Q92EG6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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