Reviewed, UniProtKB/Swiss-Prot Q92CN9 (ACKA2_LISIN)

Names and origin

Protein names

Recommended name:
    Acetate kinase 2
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	lin1132

Organism

Listeria innocua [Complete proteome] [HAMAP]

Taxonomic identifier

1642 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107576

Sequences

	Sequence		Length	Mass (Da)
	Q92CN9-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 5822544EF92CBF51	FASTA	397	43,115
	10 20 30 40 50 60 MHKIMAINAG SSSLKFQIFT MPGEEVLVKG LIERIGLPDA IFNMSFQNEK IKETRAINNH 70 80 90 100 110 120 GEAVEILLEQ LKTHQVINDL NEITGVGHRV AHGGEAFVSS CIVTDDVVKG IEDVTSLAPL 130 140 150 160 170 180 HNPANIIGIK TFRELLPNAV SVAVFDTAFH QTIPEENFLY ALPYELYEKH HIRKYGFHGT 190 200 210 220 230 240 SHKYVAGKAA EVLKKPLEKL KIISCHLGNG ASVCAIEAGK SVNTSMGFTP NAGLMMGTRS 250 260 270 280 290 300 GTIDATIIPY LVDELGYSLD EVTHMMSSES GVLGVSGISS DFRDIEIAAN EGNSRALLTL 310 320 330 340 350 360 RMFTGQICNY IGAYASAMNG CDALLFTAGV GENSPLIRKM VTEQLSYLGV TCNVTKNNAG 370 380 390 DMIISNDDEA VKVCIIPTNE ELMIARDVEK YTKQTIS

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed: 11679669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIP 11262 / Serovar 6a.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL596167 Genomic DNA. Translation: CAC96363.1.
PIR	AC1574.
RefSeq	NP_470469.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Genome annotation databases
GeneID	1129679.
GenomeReviews	Gene locus lin1132 in contig AL592022_GR.
KEGG	lin:lin1132.
NMPDR	fig|272626.1.peg.1122.
Organism-specific databases
ListiList	LIN01132.
CMR	Search...
Phylogenomic databases
HOGENOM	Q92CN9.
OMA	HKIMAIN.
Enzyme and pathway databases
BioCyc	LINN272626:LIN1132-MON.
BRENDA	2.7.2.1. 270396.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_LISIN

Accession

Primary (citable) accession number: Q92CN9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	December 1, 2001
Last modified:	November 3, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)