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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:lin1398
OrganismiListeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Taxonomic identifieri272626 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000002513 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001978561 – 450Exodeoxyribonuclease 7 large subunitAdd BLAST450

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi272626.lin1398.

Structurei

3D structure databases

ProteinModelPortaliQ92BZ3.
SMRiQ92BZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiVVFRQRD.
OrthoDBiPOG091H02EK.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92BZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQDKYLTVA AITKYIEKKF EVDPYMKQVF VRGEISNLKQ PASGHLYFTV
60 70 80 90 100
KDEFAMLRSV MFQKAVQKIG FVPEDGMNVL ITGRIGVFTK AGRYQFYAEH
110 120 130 140 150
MEPDGVGALY IQLEQLKSQL EKEGLFAEAH KKVLPSFPSK VAVVTSKTGA
160 170 180 190 200
AVRDILTTIH RRMPSVEVIV YPTVVQGDKA AQRIVENIGR INQRNDIDVM
210 220 230 240 250
IIGRGGGSLE ELWAFNEEPV VRAVYDSDVP VISAVGHETD FALSDFSADV
260 270 280 290 300
RAATPTAAAE LAVPDYRDLE ERLAERKYRL LAVTRQLLER KERALEQLKQ
310 320 330 340 350
HLILNGPKHQ LEQQMERTDY FAERLKNAFS KQVLLKQTTF NRLNDRLHYY
360 370 380 390 400
HPKKEIALQK EQIILRKQAL DKAMKQQLKD KQQAFIRQVE ALEHLSPLAL
410 420 430 440 450
LKRGFGVTYK AGELVKTVQE LEIGDNIQVK MQGGHIDAHI TAKEEDTSGN
Length:450
Mass (Da):51,119
Last modified:December 1, 2001 - v1
Checksum:i235304B13A19CE5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596168 Genomic DNA. Translation: CAC96629.1.
PIRiAE1607.
RefSeqiWP_010991514.1. NC_003212.1.

Genome annotation databases

EnsemblBacteriaiCAC96629; CAC96629; CAC96629.
KEGGilin:lin1398.
PATRICi20299527. VBILisInn102668_1430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596168 Genomic DNA. Translation: CAC96629.1.
PIRiAE1607.
RefSeqiWP_010991514.1. NC_003212.1.

3D structure databases

ProteinModelPortaliQ92BZ3.
SMRiQ92BZ3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272626.lin1398.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC96629; CAC96629; CAC96629.
KEGGilin:lin1398.
PATRICi20299527. VBILisInn102668_1430.

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiVVFRQRD.
OrthoDBiPOG091H02EK.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7L_LISIN
AccessioniPrimary (citable) accession number: Q92BZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.