Q92AI7 (STP1_LISIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine/threonine phosphatase stp
EC=3.1.3.16

Gene names

Name:	stp
Ordered Locus Names:	lin1935

Organism

Listeria innocua serovar 6a (strain CLIP 11262) [Complete proteome] [HAMAP]

Taxonomic identifier

272626 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Listeriaceae › Listeria › Listeria innocua

Protein attributes

Sequence length	252 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Protein phosphatase that dephosphorylates EF-Tu By similarity.
Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 manganese ions per subunit By similarity.
Subcellular location	Cytoplasm. Membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm Membrane
Ligand	Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 252	252	Serine/threonine phosphatase stp		PRO_0000363062
Regions
	Domain	2 – 235	234	PP2C-like
Sites
	Metal binding	36	1	Manganese 1 By similarity
	Metal binding	36	1	Manganese 2 By similarity
	Metal binding	37	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	194	1	Manganese 2 By similarity
	Metal binding	233	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q92AI7 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 7DF9B70ED0D8C623	FASTA	252	28,007
	10 20 30 40 50 60 MHAEFRTDRG RIRHHNEDNG GVFENKDKQP IVIVADGMGG HRAGDVASEM AVRLLSDAWK 70 80 90 100 110 120 ETTALLTAEE IETWLQKTIQ EVNKEIVLYA ESEMDLNGMG TTLVAAIMAQ SQVVIANVGD 130 140 150 160 170 180 SRGYLLQNDV MRQLTEDHSL VHELLRTGEI SKEDAMNHPR KNILLRALGV EGKVEVDTFV 190 200 210 220 230 240 VPFQTSDTLL LCSDGLTNMV PEAEMEEILK SKRTLSEKAD VFITKANSYG GEDNITVLLV 250 ERNLMQKGRD AS

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIP 11262.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL596170 Genomic DNA. Translation: CAC97165.1.
PIR	AE1674.
RefSeq	NP_471269.1. NC_003212.1.
3D structure databases
ProteinModelPortal	Q92AI7.
ModBase	Search...
Protein-protein interaction databases
STRING	272626.lin1935.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAC97165; CAC97165; CAC97165.
GeneID	1130626.
KEGG	lin:lin1935.
PATRIC	20300681. VBILisInn102668_1979.
Organism-specific databases
GenoList	LIN1935.
CMR	Search...
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000235782.
KO	K01090.
OMA	SDIGQQR.
ProtClustDB	CLSK564625.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
ProtoNet	Search...

Entry information

Entry name

STP1_LISIN

Accession

Primary (citable) accession number: Q92AI7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program