Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tagatose-6-phosphate kinase

Gene

lin2199

Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.UniRule annotation

Pathwayi: D-tagatose 6-phosphate degradation

This protein is involved in step 1 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Tagatose-6-phosphate kinase (lin2199), Tagatose-6-phosphate kinase (fruB)
  2. Tagatose 1,6-diphosphate aldolase (lacD)
This subpathway is part of the pathway D-tagatose 6-phosphate degradation, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate, the pathway D-tagatose 6-phosphate degradation and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi211MagnesiumCombined sources1
Binding sitei243ATPCombined sources1
Binding sitei278ATPCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi185 – 187ATPCombined sources3
Nucleotide bindingi219 – 224ATPCombined sources6
Nucleotide bindingi248 – 251ATPCombined sources4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processLactose metabolismUniRule annotation
LigandATP-bindingUniRule annotationCombined sourcesSAAS annotation, MagnesiumCombined sources, Metal-bindingCombined sources, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00704; UER00715

Names & Taxonomyi

Protein namesi
Recommended name:
Tagatose-6-phosphate kinaseUniRule annotation (EC:2.7.1.144UniRule annotation)
Gene namesi
Ordered Locus Names:lin2199Imported
OrganismiListeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)Imported
Taxonomic identifieri272626 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi

Interactioni

Protein-protein interaction databases

STRINGi272626.lin2199

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3HICX-ray2.02A2-310[»]
3IE7X-ray1.60A2-310[»]
3JULX-ray2.40A2-310[»]
3Q1YX-ray2.03A2-310[»]
ProteinModelPortaliQ929S5
SMRiQ929S5
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ929S5

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 287PfkBInterPro annotationAdd BLAST266

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili192 – 212Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the carbohydrate kinase PfkB family. LacC subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105DE4 Bacteria
COG1105 LUCA
HOGENOMiHOG000265280
KOiK00882
OMAiTAFDCGG
OrthoDBiPOG091H0F08

Family and domain databases

CDDicd01164 FruK_PfkB_like, 1 hit
Gene3Di3.40.1190.20, 1 hit
InterProiView protein in InterPro
IPR011611 PfkB_dom
IPR029056 Ribokinase-like
IPR017583 Tagatose/fructose_Pkinase
PfamiView protein in Pfam
PF00294 PfkB, 1 hit
PIRSFiPIRSF000535 1PFK/6PFK/LacC, 1 hit
SUPFAMiSSF53613 SSF53613, 1 hit
TIGRFAMsiTIGR03168 1-PFK, 1 hit

Sequencei

Sequence statusi: Complete.

Q929S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYTITLNPA IDRLLFIRGE LEKRKTNRVI KTEFDCGGKG LHVSGVLSKF
60 70 80 90 100
GIKNEALGIA GSDNLDKLYA ILKEKHINHD FLVEAGTSTR ECFVVLSDDT
110 120 130 140 150
NGSTMIPEAG FTVSQTNKDN LLKQIAKKVK KEDMVVIAGS PPPHYTLSDF
160 170 180 190 200
KELLRTVKAT GAFLGCDNSG EYLNLAVEMG VDFIKPNEDE VIAILDEKTN
210 220 230 240 250
SLEENIRTLA EKIPYLVVSL GAKGSICAHN GKLYQVIPPK VQERNDTGAG
260 270 280 290 300
DVFVGAFIAG LAMNMPITET LKVATGCSAS KVMQQDSSSF DLEAAGKLKN
310
QVSIIQLEER
Length:310
Mass (Da):33,754
Last modified:December 1, 2001 - v1
Checksum:i24D6D620C8A61EEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596171 Genomic DNA Translation: CAC97428.1
PIRiAD1707
RefSeqiWP_003763361.1, NC_003212.1

Genome annotation databases

EnsemblBacteriaiCAC97428; CAC97428; CAC97428
KEGGilin:lin2199

Similar proteinsi

Entry informationi

Entry nameiQ929S5_LISIN
AccessioniPrimary (citable) accession number: Q929S5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: February 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health