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Protein

Tagatose-6-phosphate kinase

Gene

lin2199

Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.UniRule annotation

Pathwayi: D-tagatose 6-phosphate degradation

This protein is involved in step 1 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Tagatose-6-phosphate kinase (lin2199), Tagatose-6-phosphate kinase (fruB)
  2. Tagatose 1,6-diphosphate aldolase (lacD)
This subpathway is part of the pathway D-tagatose 6-phosphate degradation, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate, the pathway D-tagatose 6-phosphate degradation and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei243 – 2431ATPCombined sources
Binding sitei278 – 2781ATPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi185 – 1873ATPCombined sources
Nucleotide bindingi219 – 2246ATPCombined sources
Nucleotide bindingi248 – 2514ATPCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Lactose metabolismUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotationCombined sourcesSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00704; UER00715.

Names & Taxonomyi

Protein namesi
Recommended name:
Tagatose-6-phosphate kinaseUniRule annotation (EC:2.7.1.144UniRule annotation)
Gene namesi
Ordered Locus Names:lin2199Imported
OrganismiListeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)Imported
Taxonomic identifieri272626 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000002513 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272626.lin2199.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3HICX-ray2.02A2-310[»]
3IE7X-ray1.60A2-310[»]
3JULX-ray2.40A2-310[»]
3Q1YX-ray2.03A2-310[»]
ProteinModelPortaliQ929S5.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ929S5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 287266PfkBInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the carbohydrate kinase PfkB family. LacC subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DE4. Bacteria.
COG1105. LUCA.
HOGENOMiHOG000265280.
KOiK00882.
OMAiTAFDCGG.
OrthoDBiPOG091H0F08.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
IPR017583. Tagatose/fructose_Pkinase.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
PIRSFiPIRSF000535. 1PFK/6PFK/LacC. 1 hit.
SUPFAMiSSF53613. SSF53613. 1 hit.
TIGRFAMsiTIGR03168. 1-PFK. 1 hit.

Sequencei

Sequence statusi: Complete.

Q929S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYTITLNPA IDRLLFIRGE LEKRKTNRVI KTEFDCGGKG LHVSGVLSKF
60 70 80 90 100
GIKNEALGIA GSDNLDKLYA ILKEKHINHD FLVEAGTSTR ECFVVLSDDT
110 120 130 140 150
NGSTMIPEAG FTVSQTNKDN LLKQIAKKVK KEDMVVIAGS PPPHYTLSDF
160 170 180 190 200
KELLRTVKAT GAFLGCDNSG EYLNLAVEMG VDFIKPNEDE VIAILDEKTN
210 220 230 240 250
SLEENIRTLA EKIPYLVVSL GAKGSICAHN GKLYQVIPPK VQERNDTGAG
260 270 280 290 300
DVFVGAFIAG LAMNMPITET LKVATGCSAS KVMQQDSSSF DLEAAGKLKN
310
QVSIIQLEER
Length:310
Mass (Da):33,754
Last modified:December 1, 2001 - v1
Checksum:i24D6D620C8A61EEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596171 Genomic DNA. Translation: CAC97428.1.
PIRiAD1707.
RefSeqiWP_003763361.1. NC_003212.1.

Genome annotation databases

EnsemblBacteriaiCAC97428; CAC97428; CAC97428.
KEGGilin:lin2199.
PATRICi20301221. VBILisInn102668_2248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596171 Genomic DNA. Translation: CAC97428.1.
PIRiAD1707.
RefSeqiWP_003763361.1. NC_003212.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3HICX-ray2.02A2-310[»]
3IE7X-ray1.60A2-310[»]
3JULX-ray2.40A2-310[»]
3Q1YX-ray2.03A2-310[»]
ProteinModelPortaliQ929S5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272626.lin2199.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC97428; CAC97428; CAC97428.
KEGGilin:lin2199.
PATRICi20301221. VBILisInn102668_2248.

Phylogenomic databases

eggNOGiENOG4105DE4. Bacteria.
COG1105. LUCA.
HOGENOMiHOG000265280.
KOiK00882.
OMAiTAFDCGG.
OrthoDBiPOG091H0F08.

Enzyme and pathway databases

UniPathwayiUPA00704; UER00715.

Miscellaneous databases

EvolutionaryTraceiQ929S5.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
IPR017583. Tagatose/fructose_Pkinase.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
PIRSFiPIRSF000535. 1PFK/6PFK/LacC. 1 hit.
SUPFAMiSSF53613. SSF53613. 1 hit.
TIGRFAMsiTIGR03168. 1-PFK. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ929S5_LISIN
AccessioniPrimary (citable) accession number: Q929S5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.