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Q92994 (TF3B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 128. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription factor IIIB 90 kDa subunit

Short name=TFIIIB90
Short name=hTFIIIB90
Alternative name(s):
B-related factor 1
Short name=BRF-1
Short name=hBRF
TAF3B2
TATA box-binding protein-associated factor, RNA polymerase III, subunit 2
Gene names
Name:BRF1
Synonyms:BRF, GTF3B, TAF3B2, TAF3C
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length677 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.

Subunit structure

TFIIIB comprises at least the TATA-binding protein (TBP) and the B-related factor 1 (BRF1/TFIIIB90). Interacts with BDP1. Ref.8

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the TFIIB family.

Contains 1 TFIIB-type zinc finger.

Sequence caution

The sequence AAC50170.1 differs from that shown. Reason: Frameshift at positions 344 and 405.

Alternative products

This entry describes 9 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q92994-1)

Also known as: hBRF1;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q92994-2)

Also known as: hBRF2;

The sequence of this isoform differs from the canonical sequence as follows:
     1-204: Missing.
     293-338: SYTAGQRKLR...EIELENSRPK → IEEGGQTEAR...CGRGGFTLCP
     339-677: Missing.
Isoform 3 (identifier: Q92994-3)

Also known as: hBRF3;

The sequence of this isoform differs from the canonical sequence as follows:
     1-204: Missing.
Isoform 4 (identifier: Q92994-4)

Also known as: hBRF4;

The sequence of this isoform differs from the canonical sequence as follows:
     159-242: NVYVLGKTFL...LLVAARMHDF → DSLRPASFPT...HLPMLGTVGC
     243-677: Missing.
Isoform 5 (identifier: Q92994-5)

The sequence of this isoform differs from the canonical sequence as follows:
     63-89: Missing.
Isoform 6 (identifier: Q92994-6)

The sequence of this isoform differs from the canonical sequence as follows:
     159-208: NVYVLGKTFL...KNHEVSMTAL → DSLRPASFPT...CPVRKFWSVG
     209-677: Missing.
Isoform 7 (identifier: Q92994-7)

The sequence of this isoform differs from the canonical sequence as follows:
     1-115: Missing.
Isoform 8 (identifier: Q92994-8)

The sequence of this isoform differs from the canonical sequence as follows:
     1-115: Missing.
     459-459: R → RRDLSMPRCAKAKSQPHFPVLAQ
Note: No experimental confirmation available.
Isoform 9 (identifier: Q92994-9)

The sequence of this isoform differs from the canonical sequence as follows:
     1-238: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 677677Transcription factor IIIB 90 kDa subunit
PRO_0000119347

Regions

Repeat91 – 172821
Repeat185 – 269852
Zinc finger2 – 3332TFIIB-type

Sites

Metal binding61Zinc By similarity
Metal binding91Zinc By similarity
Metal binding251Zinc By similarity
Metal binding281Zinc By similarity

Amino acid modifications

Modified residue3651Phosphothreonine Ref.10 Ref.11
Modified residue4501Phosphoserine Ref.10
Modified residue5531Phosphoserine Ref.9

Natural variations

Alternative sequence1 – 238238Missing in isoform 9.
VSP_045045
Alternative sequence1 – 204204Missing in isoform 2 and isoform 3.
VSP_006396
Alternative sequence1 – 115115Missing in isoform 7 and isoform 8.
VSP_044244
Alternative sequence63 – 8927Missing in isoform 5.
VSP_014697
Alternative sequence159 – 24284NVYVL…RMHDF → DSLRPASFPTWGCDLGVVTR VVTGVYPRCASRISVAGLCC LPSQEVLVCRMRGLHDMGVT VRDLWECGSPWQEGHLPMLG TVGC in isoform 4.
VSP_006399
Alternative sequence159 – 20850NVYVL…SMTAL → DSLRPASFPTWGCDLGVVTR VVTGVYPRCLHASQWPVCAA CPVRKFWSVG in isoform 6.
VSP_043835
Alternative sequence209 – 677469Missing in isoform 6.
VSP_043836
Alternative sequence243 – 677435Missing in isoform 4.
VSP_006400
Alternative sequence293 – 33846SYTAG…NSRPK → IEEGGQTEAREPPQASSWEG PSTTRRRSQLWHGCPGCGRG GFTLCP in isoform 2.
VSP_006397
Alternative sequence339 – 677339Missing in isoform 2.
VSP_006398
Alternative sequence4591R → RRDLSMPRCAKAKSQPHFPV LAQ in isoform 8.
VSP_045046
Natural variant5421V → M in a colorectal cancer sample; somatic mutation. Ref.12
VAR_035723

Experimental info

Sequence conflict881N → D in AAC50170. Ref.1
Sequence conflict1511D → V in AAC50170. Ref.1
Sequence conflict2241R → G in AAC50170. Ref.1
Sequence conflict2311A → G in AAC50170. Ref.1
Sequence conflict339 – 3402AK → R in AAC50170. Ref.1
Sequence conflict4371D → N in BAH11919. Ref.4
Sequence conflict4461E → G in BAG53298. Ref.4
Sequence conflict5941P → T in AAC50170. Ref.1
Sequence conflict6181G → E in AAC50170. Ref.1
Sequence conflict6401E → G in BAG53298. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (hBRF1) [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 5866304B879EC1DE

FASTA67773,840
        10         20         30         40         50         60 
MTGRVCRGCG GTDIELDAAR GDAVCTACGS VLEDNIIVSE VQFVESSGGG SSAVGQFVSL 

        70         80         90        100        110        120 
DGAGKTPTLG GGFHVNLGKE SRAQTLQNGR RHIHHLGNQL QLNQHCLDTA FNFFKMAVSR 

       130        140        150        160        170        180 
HLTRGRKMAH VIAACLYLVC RTEGTPHMLL DLSDLLQVNV YVLGKTFLLL ARELCINAPA 

       190        200        210        220        230        240 
IDPCLYIPRF AHLLEFGEKN HEVSMTALRL LQRMKRDWMH TGRRPSGLCG AALLVAARMH 

       250        260        270        280        290        300 
DFRRTVKEVI SVVKVCESTL RKRLTEFEDT PTSQLTIDEF MKIDLEEECD PPSYTAGQRK 

       310        320        330        340        350        360 
LRMKQLEQVL SKKLEEVEGE ISSYQDAIEI ELENSRPKAK GGLASLAKDG STEDTASSLC 

       370        380        390        400        410        420 
GEEDTEDEEL EAAASHLNKD LYRELLGGAP GSSEAAGSPE WGGRPPALGS LLDPLPTAAS 

       430        440        450        460        470        480 
LGISDSIREC ISSQSSDPKD ASGDGELDLS GIDDLEIDRY ILNESEARVK AELWMRENAE 

       490        500        510        520        530        540 
YLREQREKEA RIAKEKELGI YKEHKPKKSC KRREPIQAST AREAIEKMLE QKKISSKINY 

       550        560        570        580        590        600 
SVLRGLSSAG GGSPHREDAQ PEHSASARKL SRRRTPASRS GADPVTSVGK RLRPLVSTQP 

       610        620        630        640        650        660 
AKKVATGEAL LPSSPTLGAE PARPQAVLVE SGPVSYHADE EADEEEPDEE DGEPCVSALQ 

       670 
MMGSNDYGCD GDEDDGY 

« Hide

Isoform 2 (hBRF2) [UniParc].

Checksum: 0F56B878F16C484B
Show »

FASTA13415,159
Isoform 3 (hBRF3) [UniParc].

Checksum: EF95D8EDB737C5C4
Show »

FASTA47351,798
Isoform 4 (hBRF4) [UniParc].

Checksum: B6FC691408BA8E26
Show »

FASTA24225,922
Isoform 5 [UniParc].

Checksum: EC6958C644660237
Show »

FASTA65071,119
Isoform 6 [UniParc].

Checksum: 8761AE32A65FFE89
Show »

FASTA20822,309
Isoform 7 [UniParc].

Checksum: 9C25CDA5DFE0F90E
Show »

FASTA56261,812
Isoform 8 [UniParc].

Checksum: 9365EBA805C92B88
Show »

FASTA58464,275
Isoform 9 [UniParc].

Checksum: 340FA6DDD52479DC
Show »

FASTA43947,978

References

« Hide 'large scale' references
[1]"Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains."
Wang Z., Roeder R.G.
Proc. Natl. Acad. Sci. U.S.A. 92:7026-7030(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 264-281; 314-338; 441-469 AND 471-488.
[2]"RNA polymerase III transcription from the human U6 and adenovirus type 2 VAI promoters has different requirements for human BRF, a subunit of human TFIIIB."
Mital R., Kobayashi R., Hernandez N.
Mol. Cell. Biol. 16:7031-7042(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 248-254; 263-280; 313-320; 343-348; 380-396; 440-449; 471-488; 514-527; 538-561 AND 570-602.
[3]"Alternatively spliced hBRF variants function at different RNA polymerase III promoters."
McCulloch V., Hardin P., Peng W., Ruppert J.M., Lobo-Ruppert S.M.
EMBO J. 19:4134-4143(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4).
[4]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 7; 8 AND 9).
Tissue: Brain and Hippocampus.
[5]"The DNA sequence and analysis of human chromosome 14."
Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. expand/collapse author list , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 5 AND 6).
Tissue: Brain, Skin and Testis.
[8]"TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo."
Fairley J.A., Scott P.H., White R.J.
EMBO J. 22:5841-5850(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH BDP1.
[9]"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-553, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[10]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-365 AND SER-450, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[11]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-365, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
[12]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANT [LARGE SCALE ANALYSIS] MET-542.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U28838 mRNA. Translation: AAC50170.1. Frameshift.
U75276 mRNA. Translation: AAB38876.1.
AJ297406 mRNA. Translation: CAC04512.1.
AJ297407 mRNA. Translation: CAC04513.1.
AJ297408 mRNA. Translation: CAC04514.1.
AK096471 mRNA. Translation: BAG53298.1.
AK294899 mRNA. Translation: BAH11919.1.
AK295579 mRNA. Translation: BAG58477.1.
AL512355 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81908.1.
CH471061 Genomic DNA. Translation: EAW81911.1.
BC016743 mRNA. Translation: AAH16743.1.
BC071637 mRNA. Translation: AAH71637.1.
BC086856 mRNA. Translation: AAH86856.1.
BC103859 mRNA. Translation: AAI03860.1.
PIRI39065.
RefSeqNP_001229715.1. NM_001242786.1.
NP_001229716.1. NM_001242787.1.
NP_001229717.1. NM_001242788.1.
NP_001229718.1. NM_001242789.1.
NP_001229719.1. NM_001242790.1.
NP_001510.2. NM_001519.3.
NP_663718.1. NM_145685.2.
XP_005267620.1. XM_005267563.1.
UniGeneHs.424484.

3D structure databases

ProteinModelPortalQ92994.
SMRQ92994. Positions 3-44, 99-267, 448-492.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid109227. 14 interactions.
IntActQ92994. 2 interactions.
MINTMINT-2859415.
STRING9606.ENSP00000329029.

PTM databases

PhosphoSiteQ92994.

Polymorphism databases

DMDM20455319.

Proteomic databases

PaxDbQ92994.
PRIDEQ92994.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000327359; ENSP00000329029; ENSG00000185024. [Q92994-7]
ENST00000379937; ENSP00000369269; ENSG00000185024. [Q92994-5]
ENST00000392557; ENSP00000376340; ENSG00000185024. [Q92994-3]
ENST00000440513; ENSP00000388877; ENSG00000185024. [Q92994-8]
ENST00000446501; ENSP00000389859; ENSG00000185024. [Q92994-9]
ENST00000546474; ENSP00000448323; ENSG00000185024. [Q92994-1]
ENST00000548421; ENSP00000446707; ENSG00000185024. [Q92994-6]
GeneID2972.
KEGGhsa:2972.
UCSCuc001yql.2. human. [Q92994-1]
uc001yqr.3. human. [Q92994-6]
uc010axg.1. human. [Q92994-5]

Organism-specific databases

CTD2972.
GeneCardsGC14M105675.
HGNCHGNC:11551. BRF1.
HPAHPA051918.
MIM604902. gene.
neXtProtNX_Q92994.
PharmGKBPA164741296.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG1405.
HOVERGENHBG023540.
InParanoidQ92994.
KOK15196.
OMAKTELWMK.
OrthoDBEOG74TWZD.
PhylomeDBQ92994.
TreeFamTF324046.

Enzyme and pathway databases

ReactomeREACT_1788. Transcription.
REACT_71. Gene Expression.

Gene expression databases

ArrayExpressQ92994.
BgeeQ92994.
CleanExHS_BRF1.
GenevestigatorQ92994.

Family and domain databases

Gene3D1.10.472.10. 2 hits.
InterProIPR011665. BRF1_TBP-bd.
IPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view]
PANTHERPTHR11618. PTHR11618. 1 hit.
PfamPF07741. BRF1. 1 hit.
PF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view]
PRINTSPR00685. TIFACTORIIB.
SMARTSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMSSF47954. SSF47954. 2 hits.
PROSITEPS51134. ZF_TFIIB. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSBRF1. human.
GeneWikiBRF1_(gene).
GenomeRNAi2972.
NextBio11787.
PROQ92994.
SOURCESearch...

Entry information

Entry nameTF3B_HUMAN
AccessionPrimary (citable) accession number: Q92994
Secondary accession number(s): B3KU36 expand/collapse secondary AC list , B4DIG5, B7Z2N3, F5H5Z7, F8WA46, Q13223, Q3SYD9, Q5PR24, Q6IQ02, Q96KX3, Q9HCW6, Q9HCW7, Q9HCW8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 14

Human chromosome 14: entries, gene names and cross-references to MIM